Follow this author to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW? Smart Alerts: Get notified about major news as it happens. Carlos Alcaraz, the 23-year-old tennis phenom from Spain, combines the physicality of his countryman Rafael Nada l and the drop-shot artistry of Roger Federer, and his complete package may help him obliterate the record books. After winning the 2022 U.S. Open, Alcaraz became the youngest world No. 1 in men's tennis history.

Follow this author to personalize your feed and get instant alerts. Follow Go to your personalized feed WHY FOLLOW? Smart Alerts: Get notified about major news as it happens. Spanish midfielder Aitana Bonmatí, the reigning three-time winner of both the Best FIFA Women's Player award and the Ballon d'Or Féminin, is the best women's soccer player on the planet. She led Spain to its first women's World Cup title in 2023, and her pro team, Barcelona, has won the Liga F title seven years running and Champions League crowns in 2021, 2023, 2024, and 2026; Bonmatí has been named the Champions League Player of the Season three times.

Model-assisted interval designs such as the Keyboard design are transparent and easy to implement in phase I oncology trials. However, interim decisions based solely on data from the current dose may overlook informative signals from neighbouring doses, leading to unnecessary escalation or de-escalation. We propose the shared Keyboard design, a Bayesian model-assisted design that replaces the independent beta--binomial updating scheme at each dose with a posterior induced by a Beta kernel process using kernel-weighted pseudo-counts. The design preserves the decision structure of the Keyboard design while enabling controlled borrowing across nearby doses. To prioritise overdose control, we propose an asymmetric kernel that assigns greater weight to toxicities observed at higher doses during escalation. We further extend the proposed design to accommodate adaptive dose insertion when the initial dose grid is inadequate and time-to-event outcomes when late-onset toxicities are present. Extensive simulation studies demonstrate substantial improvements in both accuracy and safety for identifying the maximum tolerated dose. In settings involving dose insertion, the proposed design identifies inserted target doses more effectively than adaptive dose modification while maintaining a comparable modification rate.

MV Hondius, the Dutch cruise ship hit by a deadly hantavirus outbreak, has docked at its final destination in Rotterdam. Only the ship's crew were aboard for the last leg of the journey, as all passengers docked off the ship in the Canary Islands between 10 and 11 May. Rotterdam port harbour master René de Vries said 25 mobile homes kitted out with catering and satellite communications would be available for the crew to self-isolate in. Three people - a Dutch couple and a German woman - died after travelling on the ship, with two of them confirmed to have had the virus. The World Health Organization has so far reported 10 cases in total, eight confirmed and two suspected.

We consider the problem of testing properties of graphs underlying high-dimensional graphical models. We adopt the model of covariance queries introduced by Lugosi, Truszkowski, Velona, and Zwiernik (2021). We study the case when the underlying graph is a tree. The main results of the paper show that, while reconstructing the entire tree may be costly, certain global structural properties can be tested efficiently. In particular, we design randomized tests for global structural properties that use a sub-quadratic number of queries. We develop testing procedures for several fundamental properties, including the number of leaves, the maximum degree, the typical distance, and the diameter of the tree. For each property, we obtain explicit query complexity bounds that depend on the target threshold and tolerance parameters.

Bulgarian pop star Dara was met by a crowd of fans in Sofia airport on Sunday, celebrating her historic Eurovision win. The 27-year-old's tune Bangaranga won Bulgaria its first ever title in the song contest. Thank you for being here, she told fans as she arrived in the Bulgarian capital, Sofia, before adding I cannot wait to dip my toes in this atmosphere. Russia launched one of the biggest air strikes on Kyiv since the start of the war with several apartment blocks hit. Why is the Princess of Wales in Italy this week?

In this piece, we reflect on AIES 2025, and outline the conversations and presentations from a discussion session on LLMs in the context of clinical usage and human rights. This is a crosspost from the latest issue of AI Matters, published by the ACM SIAGI. This year's conference on artificial intelligence, ethics and society (AIES) took place in the north of Madrid within the 180m-high tower block that forms the vertical campus of IE University. The event kicked off with a welcome from the chairs and organising committee members, with this opening session also featuring the conference best paper awards. Topics covered during the three-day event included mitigating bias, integrating AI into the workplace, evaluating LLMs in clinical settings, power dynamics in AI ecosystems, and dataset creation.

Here's what you need to know, from why the cruise ship outbreak won't spark the next pandemic to how hantavirus spreads. Now that more than 100 passengers aboard a hantavirus -stricken luxury cruise ship have been evacuated, with 18 Americans in biocontainment units in Nebraska and Georgia, health officials around the world are working to monitor more than two dozen individuals who left the cruise and anyone with whom they might have come in close contact. So far, all of the 11 reported hantavirus cases are among passengers or crew on the ship, the World Health Organization's director-general Tedros Adhanom Ghebreyesus said at a press conference in Madrid on Tuesday. That includes three deaths resulting from the virus. Typically, hantaviruses are spread when contaminated rodent droppings and urine are stirred up in the air and breathed in.

Since 2023, Moderna and Korea University have been developing a new mRNA vaccine for hantavirus. The work has been promising so far, but a finished product isn't likely coming any time soon. US-based pharmaceutical company Moderna confirmed that it has been working on the development of hantavirus vaccines in collaboration with the Vaccine Innovation Center of Korea University College of Medicine (VIC-K). This comes after an outbreak of hantavirus occurred on a Dutch cruise ship that sailed from Argentina and disembarked its passengers and crew in the Canary Islands on May 10. At least three people aboard the MV died, and several cases were reported as serious.

Days before the cruise ship affected by a hantavirus outbreak is set to dock in southern Tenerife in the Canary Islands, locals are expressing a mix of concern and calm. According to Oceanwide Expeditions, there are currently no symptomatic individuals on board the ship. Iran's president says he has spoken to the country's Supreme Leader