In this piece, we reflect on AIES 2025, and outline the conversations and presentations from a discussion session on LLMs in the context of clinical usage and human rights. This is a crosspost from the latest issue of AI Matters, published by the ACM SIAGI. This year's conference on artificial intelligence, ethics and society (AIES) took place in the north of Madrid within the 180m-high tower block that forms the vertical campus of IE University. The event kicked off with a welcome from the chairs and organising committee members, with this opening session also featuring the conference best paper awards. Topics covered during the three-day event included mitigating bias, integrating AI into the workplace, evaluating LLMs in clinical settings, power dynamics in AI ecosystems, and dataset creation.

Here's what you need to know, from why the cruise ship outbreak won't spark the next pandemic to how hantavirus spreads. Now that more than 100 passengers aboard a hantavirus -stricken luxury cruise ship have been evacuated, with 18 Americans in biocontainment units in Nebraska and Georgia, health officials around the world are working to monitor more than two dozen individuals who left the cruise and anyone with whom they might have come in close contact. So far, all of the 11 reported hantavirus cases are among passengers or crew on the ship, the World Health Organization's director-general Tedros Adhanom Ghebreyesus said at a press conference in Madrid on Tuesday. That includes three deaths resulting from the virus. Typically, hantaviruses are spread when contaminated rodent droppings and urine are stirred up in the air and breathed in.

Image caption, Will Pep Guardiola or Mikel Arteta be lifting the Premier League trophy next month? With five games to go, Manchester City and Arsenal are only separated on goals scored at the top of the Premier League table. It's a new league now, says Gunners boss Mikel Arteta, whose side had been top of the table for 209 days until Wednesday. Manchester City's 2-1 win over Arsenal on Sunday boosted their hopes - and a 1-0 victory at Burnley on Wednesday sent them top. Who is going to win the title now?

This paper investigates the off-policy evaluation (OPE) problem from a distributional perspective. Rather than focusing solely on the expectation of the total return, as in most existing OPE methods, we aim to estimate the entire return distribution. To this end, we introduce a quantile-based approach for OPE using deep quantile process regression, presenting a novel algorithm called Deep Quantile Process regression-based Off-Policy Evaluation (DQPOPE). We provide new theoretical insights into the deep quantile process regression technique, extending existing approaches that estimate discrete quantiles to estimate a continuous quantile function. A key contribution of our work is the rigorous sample complexity analysis for distributional OPE with deep neural networks, bridging theoretical analysis with practical algorithmic implementations. We show that DQPOPE achieves statistical advantages by estimating the full return distribution using the same sample size required to estimate a single policy value using conventional methods. Empirical studies further show that DQPOPE provides significantly more precise and robust policy value estimates than standard methods, thereby enhancing the practical applicability and effectiveness of distributional reinforcement learning approaches.

We study post-training interpretability for Support Vector Machines (SVMs) built from truncated orthogonal polynomial kernels. Since the associated reproducing kernel Hilbert space is finite-dimensional and admits an explicit tensor-product orthonormal basis, the fitted decision function can be expanded exactly in intrinsic RKHS coordinates. This leads to Orthogonal Representation Contribution Analysis (ORCA), a diagnostic framework based on normalized Orthogonal Kernel Contribution (OKC) indices. These indices quantify how the squared RKHS norm of the classifier is distributed across interaction orders, total polynomial degrees, marginal coordinate effects, and pairwise contributions. The methodology is fully post-training and requires neither surrogate models nor retraining. We illustrate its diagnostic value on a synthetic double-spiral problem and on a real five-dimensional echocardiogram dataset. The results show that the proposed indices reveal structural aspects of model complexity that are not captured by predictive accuracy alone.

We study the problem of identifying change points in high-dimensional generalized linear models, and propose an approach based on sample-weighted empirical risk minimization. Our method, Weighted ERM, encodes priors on the change points via weights assigned to each sample, to obtain weighted versions of standard estimators such as M-estimators and maximum-likelihood estimators. Under mild assumptions on the data, we obtain a precise asymptotic characterization of the performance of our method for general Gaussian designs, in the high-dimensional limit where the number of samples and covariate dimension grow proportionally. We show how this characterization can be used to efficiently construct a posterior distribution over change points. Numerical experiments on both simulated and real data illustrate the efficacy of Weighted ERM compared to existing approaches, demonstrating that sample weights constructed with weakly informative priors can yield accurate change point estimators. Our method is implemented as an open-source package, weightederm, available in Python and R.

The requirement of generating predictions that exactly fulfill the fundamental symmetry of the corresponding physical quantities has profoundly shaped the development of machine-learning models for physical simulations. In many cases, models are built using constrained mathematical forms that ensure that symmetries are enforced exactly. However, unconstrained models that do not obey rotational symmetries are often found to have competitive performance, and to be able to \emph{learn} to a high level of accuracy an approximate equivariant behavior with a simple data augmentation strategy. In this paper, we introduce rigorous metrics to measure the symmetry content of the learned representations in such models, and assess the accuracy by which the outputs fulfill the equivariant condition. We apply these metrics to two unconstrained, transformer-based models operating on decorated point clouds (a graph neural network for atomistic simulations and a PointNet-style architecture for particle physics) to investigate how symmetry information is processed across architectural layers and is learned during training. Based on these insights, we establish a rigorous framework for diagnosing spectral failure modes in ML models. Enabled by this analysis, we demonstrate that one can achieve superior stability and accuracy by strategically injecting the minimum required inductive biases, preserving the high expressivity and scalability of unconstrained architectures while guaranteeing physical fidelity.

Privacy and algorithmic fairness have become two central issues in modern machine learning. Although each has separately emerged as a rapidly growing research area, their joint effect remains comparatively under-explored. In this paper, we systematically study the joint impact of differential privacy and fairness on classification in a federated setting, where data are distributed across multiple servers. Targeting demographic disparity constrained classification under federated differential privacy, we propose a two-step algorithm, namely FDP-Fair. In the special case where there is only one server, we further propose a simple yet powerful algorithm, namely CDP-Fair, serving as a computationally-lightweight alternative. Under mild structural assumptions, theoretical guarantees on privacy, fairness and excess risk control are established. In particular, we disentangle the source of the private fairness-aware excess risk into a) intrinsic cost of classification, b) cost of private classification, c) non-private cost of fairness and d) private cost of fairness. Our theoretical findings are complemented by extensive numerical experiments on both synthetic and real datasets, highlighting the practicality of our designed algorithms.

Its low-rank QTT structure arises from intrinsic spectral smoothness in continuous models, or from spectral energy concentration as the number of components D grows in discrete models. We demonstrate this on weighted sums of Bernoulli and lognormal random variables. In the latter, the approach reaches high-resolution discretizations of N = 230 frequency modes on standard hardware, far beyond the N =224 ceiling of dense implementations. These compressed representations enable efficient computation of Value at Risk (VaR) and Expected Shortfall (ES), supporting applications in quantitative finance and beyond. I. INTRODUCTION Weighted sums of independent random variables constitute a basic probabilistic model, describing macroscopic behavior arising from the aggregation of microscopic stochastic components. These models arise in a wide range of applications. Their probability distribution generally lacks a closed-form expression, and their evaluation involves multidimensional convolution integrals that are susceptible to the curse of dimensionality. Consequently, evaluating these models relies on specializednumericalmethods. Whilethese methods have been adapted for discrete settings [18, 19], they are frequently hampered by persistent Gibbs oscillations, which arise from distributional discontinuities and preclude uniform convergence [20, 21]. No existing method simultaneously achieves an accurate approximation of the exact, fully non-Gaussian target distribution while remaining scalable to larger, practically relevant system sizes. In this work, we introduce a new algorithm that combines the Fourier spectral method with tensor-network techniques.

This paper proposes a new formulation of functional Gaussian Process regression in manifolds, based on an Empirical Bayes approach, in the spatiotemporal random field context. We apply the machinery of tight Gaussian measures in separable Hilbert spaces, exploiting the invariance property of covariance kernels under the group of isometries of the manifold. The identification of these measures with infinite-product Gaussian measures is then obtained via the eigenfunctions of the Laplace-Beltrami operator on the manifold. The involved time-varying angular spectra constitute the key tool for dimension reduction in the implementation of this regression approach, adopting a suitable truncation scheme depending on the functional sample size. The simulation study and synthetic data application undertaken illustrate the finite sample and asymptotic properties of the proposed functional regression predictor.