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Predicting optical coherence tomography-derived diabetic macular edema grades from fundus photographs using deep learning

arXiv.org Machine Learning

Diabetic eye disease is one of the fastest growing causes of preventable blindness. With the advent of anti-VEGF (vascular endothelial growth factor) therapies, it has become increasingly important to detect center-involved diabetic macular edema. However, center-involved diabetic macular edema is diagnosed using optical coherence tomography (OCT), which is not generally available at screening sites because of cost and workflow constraints. Instead, screening programs rely on the detection of hard exudates as a proxy for DME on color fundus photographs, often resulting in high false positive or false negative calls. To improve the accuracy of DME screening, we trained a deep learning model to use color fundus photographs to predict DME grades derived from OCT exams. Our "OCT-DME" model had an AUC of 0.89 (95% CI: 0.87-0.91), which corresponds to a sensitivity of 85% at a specificity of 80%. In comparison, three retinal specialists had similar sensitivities (82-85%), but only half the specificity (45-50%, p<0.001 for each comparison with model). The positive predictive value (PPV) of the OCT-DME model was 61% (95% CI: 56-66%), approximately double the 36-38% by the retina specialists. In addition, we used saliency and other techniques to examine how the model is making its prediction. The ability of deep learning algorithms to make clinically relevant predictions that generally require sophisticated 3D-imaging equipment from simple 2D images has broad relevance to many other applications in medical imaging.


Adaptivity of deep ReLU network for learning in Besov and mixed smooth Besov spaces: optimal rate and curse of dimensionality

arXiv.org Machine Learning

Deep learning has shown high performances in various types of tasks from visual recognition to natural language processing, which indicates superior flexibility and adaptivity of deep learning. To understand this phenomenon theoretically, we develop a new approximation and estimation error analysis of deep learning with the ReLU activation for functions in a Besov space and its variant with mixed smoothness. The Besov space is a considerably general function space including the Holder space and Sobolev space, and especially can capture spatial inhomogeneity of smoothness. Through the analysis in the Besov space, it is shown that deep learning can achieve the minimax optimal rate and outperform any non-adaptive (linear) estimator such as kernel ridge regression, which shows that deep learning has higher adaptivity to the spatial inhomogeneity of the target function than other estimators such as linear ones. In addition to this, it is shown that deep learning can avoid the curse of dimensionality if the target function is in a mixed smooth Besov space. We also show that the dependency of the convergence rate on the dimensionality is tight due to its minimax optimality. These results support high adaptivity of deep learning and its superior ability as a feature extractor.


Visions of a generalized probability theory

arXiv.org Artificial Intelligence

In this Book we argue that the fruitful interaction of computer vision and belief calculus is capable of stimulating significant advances in both fields. From a methodological point of view, novel theoretical results concerning the geometric and algebraic properties of belief functions as mathematical objects are illustrated and discussed in Part II, with a focus on both a perspective 'geometric approach' to uncertainty and an algebraic solution to the issue of conflicting evidence. In Part III we show how these theoretical developments arise from important computer vision problems (such as articulated object tracking, data association and object pose estimation) to which, in turn, the evidential formalism is able to provide interesting new solutions. Finally, some initial steps towards a generalization of the notion of total probability to belief functions are taken, in the perspective of endowing the theory of evidence with a complete battery of estimation and inference tools to the benefit of all scientists and practitioners.


Apple launches new website devoted to privacy, showing off features of iPhones and Macs

The Independent - Tech

Apple has launched an entire website devoted to privacy as it attempts to tout the security features of its iPhones. The new site includes the option for anyone to see all of the information that their iPhones, iPads and Macs have collected about them and sent to Apple. The company had already given access to that feature to users in the European Union, in keeping with the GDPR legislation that requires all technology companies to allow people to see data collected about themselves. The feature comes as Apple totes its divergence away from the business strategy espoused by companies like Facebook and Google, which rely on collecting data about their users and making it available to advertisers. The I.F.O. is fuelled by eight electric engines, which is able to push the flying object to an estimated top speed of about 120mph.


50,000 AI & Data Science Jobs Are Vacant In India, As Candidates Don't Have The Required Skills

#artificialintelligence

India is among other countries on the forefront of AI development. But according to a recent report, we don't seem to be doing so well at filling the jobs, created by this AI development, with early talent. In a recent report by business analytics firm Great Learning, India has more than 50,000 jobs in both data science and machine learning lying vacant. Apparently, that's because we just don't have enough talent to fill them Apparently, there are twice as many jobs available in these two professions as there are job seekers. Great Learning, in exclusive insight shared with Economic Times, says this is a clear indication that Indian professionals need to upskill.


Hey Siri, Can You Make Me Think? – UX Planet

#artificialintelligence

Everything started from a conversation with a friend who one day during lunch told me "How stupid and limited Siri is. I ask her a question, and she gave me an answer. And it is so boring that I stopped using her for searching stuff. I use her only for weather and other shortcuts." "Why would you say so? Technology came a long way nowadays. You have the entire world in a metal container" I told him.


How AI is Changing the Face of Customer Service

#artificialintelligence

Having a good customer service process is an integral element to the success of any business. The way this process looks, however, is dramatically changing. Let's explore the rise of artificial intelligence (AI), chatbots and messaging for customer service. A chatbot is an artificial intelligence or a computer program that interacts with a user through text or audio. It's hard to imagine a world without chatbots since it has become part of ordinary transactions today.


Sky down: Phone and internet service not working in North West, company says

The Independent - Tech

Sky's phone and internet service has stopped working in some parts of the north west, the company says. For users across the wirral, connections have gone down and landline calls and web connections are not working, it said. Users said the issues have lasted for more than an hour at the time of publication. The I.F.O. is fuelled by eight electric engines, which is able to push the flying object to an estimated top speed of about 120mph. The giant human-like robot bears a striking resemblance to the military robots starring in the movie'Avatar' and is claimed as a world first by its creators from a South Korean robotic company Waseda University's saxophonist robot WAS-5, developed by professor Atsuo Takanishi and Kaptain Rock playing one string light saber guitar perform jam session A man looks at an exhibit entitled'Mimus' a giant industrial robot which has been reprogrammed to interact with humans during a photocall at the new Design Museum in South Kensington, London Electrification Guru Dr. Wolfgang Ziebart talks about the electric Jaguar I-PACE concept SUV before it was unveiled before the Los Angeles Auto Show in Los Angeles, California, U.S The Jaguar I-PACE Concept car is the start of a new era for Jaguar.


Chinese search firm Baidu joins global AI ethics body

The Guardian

The AI ethics body formed by five of the largest US corporations has expanded to include its first Chinese member, the search firm Baidu. The Partnership on Artificial Intelligence to Benefit People and Society – known as the Partnership on AI (PAI) – was formed in 2016 by Google, Facebook, Amazon, IBM and Microsoft to act as an umbrella organisation for the five companies to conduct research, recommend best practices and publish briefings on areas including ethics, privacy and trustworthiness of AI. In the two years since it was founded, it has grown rapidly, with more than 70 members across the private sector and academia, including Apple, which joined in 2017. But until now, it has had no representation from mainland China – although Hong Kong University's engineering school is a member of the partnership. The president of Baidu, Ya-Qin Zhang, said in a statement: "As AI technology keeps advancing and the application of AI expands, we recognise the importance of joining the global discussion around the future of AI. Ensuring AI's safety, fairness and transparency should not be an afterthought but rather highly considered at the onset of every project or system we build."


GITEX 2018: AI strategy tips from Google, LinkedIn, and Microsoft Internet of Business

#artificialintelligence

Sooraj Shah reports from Gitex Technology Week 2018 in Dubai on the lessons that some of technology's biggest names have learned from implementing artificial intelligence. Representatives from Google, LinkedIn and Microsoft took part in a panel discussion at GITEX 2018, the biggest technology conference in the United Arab Emirates, this week – and it was clear from the discussion that they are all betting big on AI. LinkedIn, the social network that was purchased by Microsoft in 2016 for $26.2 billion, may not be the first name that springs to mind when it comes to artificial intelligence. However, according to Igor Perisic, chief data officer (CDO) at the network, "AI is like oxygen for [its] product. "Without it, we wouldn't be where we are.