As we look back on 2025, the world experienced a year of both remarkable achievement and profound challenge in global health. Multilateralism, science and solidarity were tested as never before, underscoring a fundamental truth: International cooperation is not optional. It is essential if we are to protect and promote health for everyone, everywhere in 2026 and beyond. Perhaps the most significant milestone was the adoption by WHO Member States of the Pandemic Agreement, a landmark step towards making the world safer from future pandemics. Alongside this, amendments to the International Health Regulations came into force, including a new "pandemic emergency" alert level designed to trigger stronger global cooperation.

As Large Language Models (LLMs) become increasingly integrated into everyday life and information ecosystems, concerns about their implicit biases continue to persist. While prior work has primarily examined socio-demographic and left--right political dimensions, little attention has been paid to how LLMs align with broader geopolitical value systems, particularly the democracy--authoritarianism spectrum. In this paper, we propose a novel methodology to assess such alignment, combining (1) the F-scale, a psychometric tool for measuring authoritarian tendencies, (2) FavScore, a newly introduced metric for evaluating model favorability toward world leaders, and (3) role-model probing to assess which figures are cited as general role-models by LLMs. We find that LLMs generally favor democratic values and leaders, but exhibit increased favorability toward authoritarian figures when prompted in Mandarin. Further, models are found to often cite authoritarian figures as role models, even outside explicit political contexts. These results shed light on ways LLMs may reflect and potentially reinforce global political ideologies, highlighting the importance of evaluating bias beyond conventional socio-political axes. Our code is available at: https://github.com/irenestrauss/Democratic-Authoritarian-Bias-LLMs.

Safeguard models help large language models (LLMs) detect and block harmful content, but most evaluations remain English-centric and overlook linguistic and cultural diversity. Existing multilingual safety benchmarks often rely on machine-translated English data, which fails to capture nuances in low-resource languages. Southeast Asian (SEA) languages are underrepresented despite the region's linguistic diversity and unique safety concerns, from culturally sensitive political speech to region-specific misinformation. Addressing these gaps requires benchmarks that are natively authored to reflect local norms and harm scenarios. We introduce SEA-SafeguardBench, the first human-verified safety benchmark for SEA, covering eight languages, 21,640 samples, across three subsets: general, in-the-wild, and content generation. The experimental results from our benchmark demonstrate that even state-of-the-art LLMs and guardrails are challenged by SEA cultural and harm scenarios and underperform when compared to English texts.

Artificial intelligence systems are increasingly deployed in biomedical research. However, current evaluation frameworks may inadequately assess their effectiveness as research collaborators. This rapid review examines benchmarking practices for AI systems in preclinical biomedical research. Three major databases and two preprint servers were searched from January 1, 2018 to October 31, 2025, identifying 14 benchmarks that assess AI capabilities in literature understanding, experimental design, and hypothesis generation. The results revealed that all current benchmarks assess isolated component capabilities, including data analysis quality, hypothesis validity, and experimental protocol design. However, authentic research collaboration requires integrated workflows spanning multiple sessions, with contextual memory, adaptive dialogue, and constraint propagation. This gap implies that systems excelling on component benchmarks may fail as practical research co-pilots. A process-oriented evaluation framework is proposed that addresses four critical dimensions absent from current benchmarks: dialogue quality, workflow orchestration, session continuity, and researcher experience. These dimensions are essential for evaluating AI systems as research co-pilots rather than as isolated task executors.

Timely assessment of current conditions is essential especially for small, open economies such as Singapore, where external shocks transmit rapidly to domestic activity. We develop a real-time nowcasting framework for quarterly GDP growth using a high-dimensional panel of approximately 70 indicators, encompassing economic and financial indicators over 1990Q1-2023Q2. The analysis covers penalized regressions, dimensionality-reduction methods, ensemble learning algorithms, and neural architectures, benchmarked against a Random Walk, an AR(3), and a Dynamic Factor Model. The pipeline preserves temporal ordering through an expanding-window walk-forward design with Bayesian hyperparameter optimization, and uses moving block-bootstrap procedures both to construct prediction intervals and to obtain confidence bands for feature-importance measures. It adopts model-specific and XAI-based explainability tools. A Model Confidence Set procedure identifies statistically superior learners, which are then combined through simple, weighted, and exponentially weighted schemes; the resulting time-varying weights provide an interpretable representation of model contributions. Predictive ability is assessed via Giacomini-White tests. Empirical results show that penalized regressions, dimensionality-reduction models, and GRU networks consistently outperform all benchmarks, with RMSFE reductions of roughly 40-60%; aggregation delivers further gains. Feature-attribution methods highlight industrial production, external trade, and labor-market indicators as dominant drivers of Singapore's short-run growth dynamics.

Vision-Language Models (VLMs) excel in multimodal tasks but often exhibit Western-centric biases, limiting their effectiveness in culturally diverse regions like Southeast Asia (SEA). To address this, we introduce RICE-VL, a novel benchmark evaluating VLM cultural understanding across 11 ASEAN countries. RICE-VL includes over 28,000 human-curated Visual Question Answering (VQA) samples -- covering True or False, Fill-in-the-Blank, and open-ended formats -- and 1,000 image-bounding box pairs for Visual Grounding, annotated by culturally informed experts across 14 sub-ground categories. We propose SEA-LAVE, an extension of the LAVE metric, assessing textual accuracy, cultural alignment, and country identification. Evaluations of six open- and closed-source VLMs reveal significant performance gaps in low-resource countries and abstract cultural domains. The Visual Grounding task tests models' ability to localize culturally significant elements in complex scenes, probing spatial and contextual accuracy. RICE-VL exposes limitations in VLMs' cultural comprehension and highlights the need for inclusive model development to better serve diverse global populations.

For example, in the Pandemic Response Challenge experiment, the context consisted of data about the geographic region for which the predictions were made, e.g., historical data of COVID-19 cases and intervention policies; actions were future schedules of intervention policies for the region; and outcomes were predicted future cases of COVID-19 along with the stringency

Often, multilingual language models are trained with the objective to map semantically similar content (in different languages) in the same latent space. In this paper, we show a nuance in this training objective, and find that by changing the language of the input query, we can improve the question answering ability of language models. Our contributions are two-fold. First, we introduce the term Language Specific Knowledge (LSK) to denote queries that are best answered in an "expert language" for a given LLM, thereby enhancing its question-answering ability. We introduce the problem of language selection -- for some queries, language models can perform better when queried in languages other than English, sometimes even better in low-resource languages -- and the goal is to select the optimal language for the query. Second, we introduce simple to strong baselines to test this problem. Additionally, as a first-pass solution to this novel problem, we design LSKExtractor to benchmark the language-specific knowledge present in a language model and then exploit it during inference. To test our framework, we employ three datasets that contain knowledge about both cultural and social behavioral norms. Overall, LSKExtractor achieves up to 10% relative improvement across datasets, and is competitive against strong baselines, while being feasible in real-world settings. Broadly, our research contributes to the open-source development (https://github.com/agarwalishika/LSKExtractor/tree/main) of language models that are inclusive and more aligned with the cultural and linguistic contexts in which they are deployed.

Artificial intelligence (AI) is diffusing globally at unprecedented speed, but adoption remains uneven. Frontier Large Language Models (LLMs) are known to perform poorly on low-resource languages due to data scarcity. We hypothesize that this performance deficit reduces the utility of AI, thereby slowing adoption in Low-Resource Language Countries (LRLCs). To test this, we use a weighted regression model to isolate the language effect from socioeconomic and demographic factors, finding that LRLCs have a share of AI users that is approximately 20% lower relative to their baseline. These results indicate that linguistic accessibility is a significant, independent barrier to equitable AI diffusion.

Coral reefs are vital yet vulnerable ecosystems that require continuous monitoring to support conservation. While coral reef images provide essential information in coral monitoring, interpreting such images remains challenging due to the need for domain expertise. Visual Question Answering (VQA), powered by Large Vision-Language Models (LVLMs), has great potential in user-friendly interaction with coral reef images. However, applying VQA to coral imagery demands a dedicated dataset that addresses two key challenges: domain-specific annotations and multidimensional questions. In this work, we introduce CoralVQA, the first large-scale VQA dataset for coral reef analysis. It contains 12,805 real-world coral images from 67 coral genera collected from 3 oceans, along with 277,653 question-answer pairs that comprehensively assess ecological and health-related conditions. To construct this dataset, we develop a semi-automatic data construction pipeline in collaboration with marine biologists to ensure both scalability and professional-grade data quality. CoralVQA presents novel challenges and provides a comprehensive benchmark for studying vision-language reasoning in the context of coral reef images. By evaluating several state-of-the-art LVLMs, we reveal key limitations and opportunities. These insights form a foundation for future LVLM development, with a particular emphasis on supporting coral conservation efforts.