Background: Heart failure (HF) research is constrained by limited access to large, shareable datasets due to privacy regulations and institutional barriers. Synthetic data generation offers a promising solution to overcome these challenges while preserving patient confidentiality. Methods: We generated synthetic HF datasets from institutional data comprising 12,552 unique patients using five deep learning models: tabular variational autoencoder (TVAE), normalizing flow, ADSGAN, SurvivalGAN, and tabular denoising diffusion probabilistic models (TabDDPM). We comprehensively evaluated synthetic data utility through statistical similarity metrics, survival prediction using machine learning and privacy assessments. Results: SurvivalGAN and TabDDPM demonstrated high fidelity to the original dataset, exhibiting similar variable distributions and survival curves after applying histogram equalization. SurvivalGAN (C-indices: 0.71-0.76) and TVAE (C-indices: 0.73-0.76) achieved the strongest performance in survival prediction evaluation, closely matched real data performance (C-indices: 0.73-0.76). Privacy evaluation confirmed protection against re-identification attacks. Conclusions: Deep learning-based synthetic data generation can produce high-fidelity, privacy-preserving HF datasets suitable for research applications. This publicly available synthetic dataset addresses critical data sharing barriers and provides a valuable resource for advancing HF research and predictive modeling.

Background and Objective: Radiation pneumonitis (RP) is a side effect of thoracic radiation therapy. Recently, Machine learning (ML) models enhanced with radiomic and dosiomic features provide better predictions by incorporating spatial information beyond DVHs. However, to improve the clinical decision process, we propose to use uncertainty quantification (UQ) to improve the confidence in model prediction. This study evaluates the impact of post hoc UQ methods on the discriminative performance and calibration of ML models for RP prediction. Methods: This study evaluated four ML models: logistic regression (LR), support vector machines (SVM), extreme gradient boosting (XGB), and random forest (RF), using radiomic, dosiomic, and dosimetric features to predict RP. We applied UQ methods, including Patt scaling, isotonic regression, Venn-ABERS predictor, and Conformal Prediction, to quantify uncertainty. Model performance was assessed through Area Under the Receiver Operating Characteristic curve (AUROC), Area Under the Precision-Recall Curve (AUPRC), and Adaptive Calibration Error (ACE) using Leave-One-Out Cross-Validation (LOO-CV). Results: UQ methods enhanced predictive performance, particularly for high-certainty predictions, while also improving calibration. Radiomic and dosiomic features increased model accuracy but introduced calibration challenges, especially for non-linear models like XGB and RF. Performance gains from UQ methods were most noticeable at higher certainty thresholds. Conclusion: Integrating UQ into ML models with radiomic and dosiomic features improves both predictive accuracy and calibration, supporting more reliable clinical decision-making. The findings emphasize the value of UQ methods in enhancing applicability of predictive models for RP in healthcare settings.

Thailand has targeted to achieve carbon neutrality by 2050 when the power grid will need to accommodate 50% share of renewable electricity generation capacity; see [Ene21]. The most recent draft of Power Development Plan 2024 (PDP2024) for 2024 - 2037 from [Ene24] proposes to add a new solar generation capacity of approximately 24,400 MWp (more than 4 times the amount issued in the previous Alternative Energy Development Plan 2015-2036 (AEDP2015) at 6,000 MWp, shown in [Dep15, p.9]. This amount does not yet include behind-the-meter, self-generation solar installed capacities of the prosumers, which is expected to increase at an accelerating rate. Solar integration into the power grid with such a sharprising amount will pose technical challenges to the operation and control of the transmission and distribution networks, carried out by the transmission system operator (TSO) and distribution system operator (DSO), as presented in [OB16]. Hence, TSO in Thailand will need an effective means to estimate the solar power generation across the entire transmission network, on an hourly basis, or even finer time resolution, to provide economic hour-to-hour generation dispatch for load following the total net load of the transmission, and to prepare sufficient system flexibility (i.e., ramp-rate capability of the thermal and hydropower plants, or energy storage systems) to cope with the net load fluctuation due to solar generation intermittency for maintaining system frequency stability, concurrently, in its operation. For DSO, a significant amount of reverse power flow when self-generation from solar exceeds self-consumption can lead to technical concerns of voltage regulation and equipment overloading problems. The near real-time estimation of solar generation in each distribution area will enable DSO to activate proper network switching or reconfiguring to mitigate such fundamental concerns to ensure its reliable operation.

Startling video footage capturing the tragic moment a robotic arm fatally crushed a worker at a factory in Thailand has emerged today. The harrowing incident unfolded at the Vandapac factory located in Thailand's Chonburi province on March 27. The unsuspecting worker appeared to be laying out sheets of material when the arm forcefully swung down and pinned him against a bench. Unsettling CCTV footage shows how the victim was incapacitated beneath the hulking metal device as a fellow employee continued working across the room, seemingly unaware of the catastrophe unfolding just behind him. Emergency responders swiftly intervened after the alarm was eventually raised, releasing the man before administering critical aid and rushing him to Chonburi Hospital.