Large language models and multilingual machine translation (MT) systems increasingly drive access to information, yet many languages of the tribal communities remain effectively invisible in these technologies. This invisibility exacerbates existing structural inequities in education, governance, and digital participation. We present AdiBhashaa, a community-driven initiative that constructs the first open parallel corpora and baseline MT systems for four major Indian tribal languages-Bhili, Mundari, Gondi, and Santali. This work combines participatory data creation with native speakers, human-in-the-loop validation, and systematic evaluation of both encoder-decoder MT models and large language models. In addition to reporting technical findings, we articulate how AdiBhashaa illustrates a possible model for more equitable AI research: it centers local expertise, builds capacity among early-career researchers from marginalized communities, and foregrounds human validation in the development of language technologies.

The interaction between proteins and nucleic acids is crucial for processes that sustain cellular function, including DNA maintenance and the regulation of gene expression and translation. Amino acid mutat ions in protein - nucleic acid complexes often lead to vital disease s . Experimental techniques have their own specific limitations in predicting mutational effects in protein - nucleic acid complexes . In this study, we compiled a large dataset of 1951 mutations including both protein - DNA and protein - RNA complexes and integrate d structural and sequential features to build a deep learning - based regression model named DeepPNI . This model estimates mutation - induced binding free energy changes in protein - nucleic aci d complexes . The structural feature s are encoded via edge - aware RGCN and the sequential feature s are extracted using protein language model ESM - 2. W e have achieved a high average Pearson correlation coeffi cient (PCC) of 0.76 in the large dataset via five - fold cross - validation. Consistent performance across individual dataset of protein - DNA, protein - RNA complexes, and different experimental temperature split dataset make the model g eneralizable . Our model showed g ood performance in complex - based five - fold cross - validation, which prove d its robustness. In addition, DeepPNI outperform ed in e xternal dataset validation, and compar ison with existing tools .

Early detection of disease outbreaks is crucial to ensure timely intervention by the health authorities. Due to the challenges associated with traditional indicator-based surveillance, monitoring informal sources such as online media has become increasingly popular. However, owing to the number of online articles getting published everyday, manual screening of the articles is impractical. To address this, we propose Health Sentinel. It is a multi-stage information extraction pipeline that uses a combination of ML and non-ML methods to extract events-structured information concerning disease outbreaks or other unusual health events-from online articles. The extracted events are made available to the Media Scanning and Verification Cell (MSVC) at the National Centre for Disease Control (NCDC), Delhi for analysis, interpretation and further dissemination to local agencies for timely intervention. From April 2022 till date, Health Sentinel has processed over 300 million news articles and identified over 95,000 unique health events across India of which over 3,500 events were shortlisted by the public health experts at NCDC as potential outbreaks.

In this study, we tackle the challenging task of predicting secondary structures from protein primary sequences, a pivotal initial stride towards predicting tertiary structures, while yielding crucial insights into protein activity, relationships, and functions. Existing methods often utilize extensive sets of unlabeled amino acid sequences. However, these approaches neither explicitly capture nor harness the accessible protein 3D structural data, which is recognized as a decisive factor in dictating protein functions. To address this, we utilize protein residue graphs and introduce various forms of sequential or structural connections to capture enhanced spatial information. We adeptly combine Graph Neural Networks (GNNs) and Language Models (LMs), specifically utilizing a pre-trained transformer-based protein language model to encode amino acid sequences and employing message-passing mechanisms like GCN and R-GCN to capture geometric characteristics of protein structures. Employing convolution within a specific node's nearby region, including relations, we stack multiple con-volutional layers to efficiently learn combined insights from the protein's spatial graph, revealing intricate interconnections and dependencies in its structural To assess our model's performance, we employed the training dataset provided by NetSurfP-2.0, which outlines secondary structure in 3-and 8-states. Extensive experiments show that our proposed model, SSRGNet surpasses the baseline on f1-scores. Introduction Proteins serve as essential components within cells and are involved in various applications, spanning from therapeutics to materials. They are composed of a sequence of amino acids that fold into distinct shapes. With the development of affordable sequencing technologies [1, 2], a substantial number of novel protein sequences have been identified in recent times. However, annotating the functional properties of a newly discovered protein sequence is still a laborious and expensive process. Thus, there is a need for reliable and efficient computational methods to accurately predict and assign functions to proteins, thereby bridging the gap between sequence information and functional knowledge. The analysis of protein structure, particularly the tertiary structure, is highly significant for practical applications related to proteins, such as understanding their functions and designing drugs [3].

Vision-language models (VLMs) have demonstrated impressive generalization across multimodal tasks, yet most evaluation benchmarks remain Western-centric, leaving open questions about their performance in culturally diverse and multilingual settings. To address this gap, we introduce IndicVisionBench, the first large-scale benchmark centered on the Indian subcontinent. Our final benchmark consists of a total of 5K images and 37K+ QA pairs across 13 culturally grounded topics. In addition, we release a paired parallel corpus of annotations across 10 Indic languages, creating a unique resource for analyzing cultural and linguistic biases in VLMs. We evaluate a broad spectrum of 8 models, from proprietary closed-source systems to open-weights medium and large-scale models. Our experiments reveal substantial performance gaps, underscoring the limitations of current VLMs in culturally diverse contexts. By centering cultural diversity and multilinguality, IndicVisionBench establishes a reproducible evaluation framework that paves the way for more inclusive multimodal research. Vision-language models (VLMs) (Bai et al., 2023; Chen et al., 2024; Lu et al., 2024; Wang et al., 2024b; Laurenc on et al., 2024; Tong et al., 2024; Xue et al., 2024) have demonstrated strong performance across a variety of multimodal tasks. However, existing benchmarks (Antol et al., 2015; Fu et al., 2023; Goyal et al., 2017) remain heavily Western-centric, limiting our understanding of how these models generalize to culturally diverse and multilingual settings. While some recent efforts partially cover this diversity (Romero et al., 2024; Nayak et al., 2024; V ayani et al., 2025), a systematic, large-scale benchmark capturing India-specific cultural concepts across multiple languages is still lacking. To address this gap, we introduce IndicVisionBench, a culturally grounded evaluation benchmark tailored for the Indian subcontinent. To the best of our knowledge, this is the first large-scale benchmark explicitly designed to assess VLMs in the context of Indian culture and languages. We use states as a proxy for cultural groups following prior works (Adilazuarda et al., 2024; Nayak et al., 2024).

The rapid advancement of large language models(LLMs) has intensified the need for domain and culture specific evaluation. Existing benchmarks are largely Anglocentric and domain-agnostic, limiting their applicability to India-centric contexts. To address this gap, we introduce BhashaBench V1, the first domain-specific, multi-task, bilingual benchmark focusing on critical Indic knowledge systems. BhashaBench V1 contains 74,166 meticulously curated question-answer pairs, with 52,494 in English and 21,672 in Hindi, sourced from authentic government and domain-specific exams. It spans four major domains: Agriculture, Legal, Finance, and Ayurveda, comprising 90+ subdomains and covering 500+ topics, enabling fine-grained evaluation. Evaluation of 29+ LLMs reveals significant domain and language specific performance gaps, with especially large disparities in low-resource domains. For instance, GPT-4o achieves 76.49% overall accuracy in Legal but only 59.74% in Ayurveda. Models consistently perform better on English content compared to Hindi across all domains. Subdomain-level analysis shows that areas such as Cyber Law, International Finance perform relatively well, while Panchakarma, Seed Science, and Human Rights remain notably weak. BhashaBench V1 provides a comprehensive dataset for evaluating large language models across India's diverse knowledge domains. It enables assessment of models' ability to integrate domain-specific knowledge with bilingual understanding. All code, benchmarks, and resources are publicly available to support open research.

We present a long-term deployment study of a machine vision-based anomaly detection system for failure prediction in a steel rolling mill. The system integrates industrial cameras to monitor equipment operation, alignment, and hot bar motion in real time along the process line. Live video streams are processed on a centralized video server using deep learning models, enabling early prediction of equipment failures and process interruptions, thereby reducing unplanned breakdown costs. Server-based inference minimizes the computational load on industrial process control systems (PLCs), supporting scalable deployment across production lines with minimal additional resources. By jointly analyzing sensor data from data acquisition systems and visual inputs, the system identifies the location and probable root causes of failures, providing actionable insights for proactive maintenance. This integrated approach enhances operational reliability, productivity, and profitability in industrial manufacturing environments.

Language Models (LMs) are indispensable tools shaping modern workflows, but their global effectiveness depends on understanding local socio-cultural contexts. To address this, we introduce SANSKRITI, a benchmark designed to evaluate language models' comprehension of India's rich cultural diversity. Comprising 21,853 meticulously curated question-answer pairs spanning 28 states and 8 union territories, SANSKRITI is the largest dataset for testing Indian cultural knowledge. It covers sixteen key attributes of Indian culture: rituals and ceremonies, history, tourism, cuisine, dance and music, costume, language, art, festivals, religion, medicine, transport, sports, nightlife, and personalities, providing a comprehensive representation of India's cultural tapestry. We evaluate SANSKRITI on leading Large Language Models (LLMs), Indic Language Models (ILMs), and Small Language Models (SLMs), revealing significant disparities in their ability to handle culturally nuanced queries, with many models struggling in region-specific contexts. By offering an extensive, culturally rich, and diverse dataset, SANSKRITI sets a new standard for assessing and improving the cultural understanding of LMs.

For doctors to truly trust artificial intelligence, it can't be a black box. They need to understand its reasoning, almost as if they were consulting a colleague. We created HistoLens1 to be that transparent, collaborative partner. It allows a pathologist to simply ask a question in plain English about a tissue slide--just as they would ask a trainee. Our system intelligently translates this question into a precise query for its AI engine, which then provides a clear, structured report. But it doesn't stop there. If a doctor ever asks, "Why?", HistoLens can instantly provide a 'visual proof' for any finding--a heatmap that points to the exact cells and regions the AI used for its analysis. We've also ensured the AI focuses only on the patient's tissue, just like a trained pathologist would, by teaching it to ignore distracting background noise. The result is a workflow where the pathologist remains the expert in charge, using a trustworthy AI assistant to verify their insights and make faster, more confident diagnoses.

We introduce DRISHTIKON, a first-of-its-kind multimodal and multilingual benchmark centered exclusively on Indian culture, designed to evaluate the cultural understanding of generative AI systems. Unlike existing benchmarks with a generic or global scope, DRISHTIKON offers deep, fine-grained coverage across India's diverse regions, spanning 15 languages, covering all states and union territories, and incorporating over 64,000 aligned text-image pairs. The dataset captures rich cultural themes including festivals, attire, cuisines, art forms, and historical heritage amongst many more. We evaluate a wide range of vision-language models (VLMs), including open-source small and large models, proprietary systems, reasoning-specialized VLMs, and Indic-focused models, across zero-shot and chain-of-thought settings. Our results expose key limitations in current models' ability to reason over culturally grounded, multimodal inputs, particularly for low-resource languages and less-documented traditions. DRISHTIKON fills a vital gap in inclusive AI research, offering a robust testbed to advance culturally aware, multimodally competent language technologies.