Tuberculosis (TB) is a infectious global health challenge. Chest X-rays are a standard method for TB screening, yet many countries face a critical shortage of radiologists capable of interpreting these images. Machine learning offers an alternative, as it can automate tasks such as disease diagnosis, and report generation. However, traditional approaches rely on task-specific models, which cannot utilize the interdependence between tasks. Building a multi-task model capable of performing multiple tasks poses additional challenges such as scarcity of multimodal data, dataset imbalance, and negative transfer. To address these challenges, we propose PaliGemma-CXR, a multi-task multimodal model capable of performing TB diagnosis, object detection, segmentation, report generation, and VQA. Starting with a dataset of chest X-ray images annotated with TB diagnosis labels and segmentation masks, we curated a multimodal dataset to support additional tasks. By finetuning PaliGemma on this dataset and sampling data using ratios of the inverse of the size of task datasets, we achieved the following results across all tasks: 90.32% accuracy on TB diagnosis and 98.95% on close-ended VQA, 41.3 BLEU score on report generation, and a mAP of 19.4 and 16.0 on object detection and segmentation, respectively. These results demonstrate that PaliGemma-CXR effectively leverages the interdependence between multiple image interpretation tasks to enhance performance.

We consider the problem of crystal materials generation using language models (LMs). A key step is to convert 3D crystal structures into 1D sequences to be processed by LMs. Prior studies used the crystallographic information framework (CIF) file stream, which fails to ensure SE(3) and periodic invariance and may not lead to unique sequence representations for a given crystal structure. Here, we propose a novel method, known as Mat2Seq, to tackle this challenge. Mat2Seq converts 3D crystal structures into 1D sequences and ensures that different mathematical descriptions of the same crystal are represented in a single unique sequence, thereby provably achieving SE(3) and periodic invariance. Experimental results show that, with language models, Mat2Seq achieves promising performance in crystal structure generation as compared with prior methods.

As large language models (LLMs) become increasingly integrated into daily life, ensuring their cultural sensitivity and inclusivity is paramount. We introduce our dataset, a year-long community-driven project covering all 22 Arab countries. The dataset includes instructions (input, response pairs) in both Modern Standard Arabic (MSA) and dialectal Arabic (DA), spanning 20 diverse topics. Built by a team of 44 researchers across the Arab world, all of whom are authors of this paper, our dataset offers a broad, inclusive perspective. We use our dataset to evaluate the cultural and dialectal capabilities of several frontier LLMs, revealing notable limitations. For instance, while closed-source LLMs generally exhibit strong performance, they are not without flaws, and smaller open-source models face greater challenges. Moreover, certain countries (e.g., Egypt, the UAE) appear better represented than others (e.g., Iraq, Mauritania, Yemen). Our annotation guidelines, code, and data for reproducibility are publicly available.

Legal systems worldwide continue to struggle with overwhelming caseloads, limited judicial resources, and growing complexities in legal proceedings. Artificial intelligence (AI) offers a promising solution, with Legal Judgment Prediction (LJP) -- the practice of predicting a court's decision from the case facts -- emerging as a key research area. However, existing datasets often formulate the task of LJP unrealistically, not reflecting its true difficulty. They also lack high-quality annotation essential for legal reasoning and explainability. To address these shortcomings, we introduce AnnoCaseLaw, a first-of-its-kind dataset of 471 meticulously annotated U.S. Appeals Court negligence cases. Each case is enriched with comprehensive, expert-labeled annotations that highlight key components of judicial decision making, along with relevant legal concepts. Our dataset lays the groundwork for more human-aligned, explainable LJP models. We define three legally relevant tasks: (1) judgment prediction; (2) concept identification; and (3) automated case annotation, and establish a performance baseline using industry-leading large language models (LLMs). Our results demonstrate that LJP remains a formidable task, with application of legal precedent proving particularly difficult. Code and data are available at https://github.com/anonymouspolar1/annocaselaw.

The proliferation of LLM bias probes introduces three significant challenges: (1) we lack principled criteria for choosing appropriate probes, (2) we lack a system for reconciling conflicting results across probes, and (3) we lack formal frameworks for reasoning about when (and why) probe results will generalize to real user behavior. We address these challenges by systematizing LLM social bias probing using actionable insights from social sciences. We then introduce EcoLevels - a framework that helps (a) determine appropriate bias probes, (b) reconcile conflicting findings across probes, and (c) generate predictions about bias generalization. Overall, we ground our analysis in social science research because many LLM probes are direct applications of human probes, and these fields have faced similar challenges when studying social bias in humans. Based on our work, we suggest how the next generation of LLM bias probing can (and should) benefit from decades of social science research.

We introduce a new method to identify emerging concepts in large text corpora. By analyzing changes in the heatmaps of the underlying embedding space, we are able to detect these concepts with high accuracy shortly after they originate, in turn outperforming common alternatives. We further demonstrate the utility of our approach by analyzing speeches in the U.S. Senate from 1941 to 2015. Our results suggest that the minority party is more active in introducing new concepts into the Senate discourse. We also identify specific concepts that closely correlate with the Senators' racial, ethnic, and gender identities. An implementation of our method is publicly available.

IEEE ROBOTICS AND AUTOMA TION LETTERS 1 Dynamically Local-Enhancement Planner for Large-Scale Autonomous Driving Nanshan Deng, Weitao Zhou, Bo Zhang, Junze Wen, Kun Jiang, Zhong Cao, Diange Y ang Abstract --Current autonomous vehicles operate primarily within limited regions, but there is increasing demand for broader applications. However, as models scale, their limited capacity becomes a significant challenge for adapting to novel scenarios. It is increasingly difficult to improve models for new situations using a single monolithic model. T o address this issue, we introduce the concept of dynamically enhancing a basic driving planner with local driving data, without permanently modifying the planner itself. This approach, termed the Dynamically Local-Enhancement (DLE) Planner, aims to improve the scalability of autonomous driving systems without significantly expanding the planner's size. Our approach introduces a position-varying Markov Decision Process formulation coupled with a graph neural network that extracts region-specific driving features from local observation data. The learned features describe the local behavior of the surrounding objects, which is then leveraged to enhance a basic reinforcement learning-based policy. We evaluated our approach in multiple scenarios and compared it with a one-for-all driving model. The results show that our method outperforms the baseline policy in both safety (collision rate) and average reward, while maintaining a lighter scale.

Simulating prospective magnetic resonance imaging (MRI) scans from a given individual brain image is challenging, as it requires accounting for canonical changes in aging and/or disease progression while also considering the individual brain's current status and unique characteristics. While current deep generative models can produce high-resolution anatomically accurate templates for population-wide studies, their ability to predict future aging trajectories for individuals remains limited, particularly in capturing subject-specific neuroanatomical variations over time. In this study, we introduce Individualized Brain Synthesis (InBrainSyn), a framework for synthesizing high-resolution subject-specific longitudinal MRI scans that simulate neurodegeneration in both Alzheimer's disease (AD) and normal aging. InBrainSyn uses a parallel transport algorithm to adapt the population-level aging trajectories learned by a generative deep template network, enabling individualized aging synthesis. As InBrainSyn uses diffeomorphic transformations to simulate aging, the synthesized images are topologically consistent with the original anatomy by design. We evaluated InBrainSyn both quantitatively and qualitatively on AD and healthy control cohorts from the Open Access Series of Imaging Studies - version 3 dataset. Experimentally, InBrainSyn can also model neuroanatomical transitions between normal aging and AD. An evaluation of an external set supports its generalizability. Overall, with only a single baseline scan, InBrainSyn synthesizes realistic 3D spatiotemporal T1w MRI scans, producing personalized longitudinal aging trajectories. The code for InBrainSyn is available at: https://github.com/Fjr9516/InBrainSyn.

Clinical knowledge is the collection of information learned from studies on the causes, prognosis, diagnosis, and treatment of diseases. This type of knowledge can improve curing performances, and promote physical health. With the emergence of large language models (LLMs), medical artificial intelligence (medical AI), which aims to apply academic medical AI systems to real-world medical scenarios, has entered a new age of development, resulting in excellent works such as DoctorGPT and Pangu-Drug from academic and industrial researches. However, the field lacks a comprehensive compendium and comparison of building medical AI systems from academia and industry. Therefore, this survey focuses on the building paradigms of medical AI systems including the use of clinical databases, datasets, training pipelines, integrating medical knowledge graphs, system applications, and evaluation systems. We hope that this survey can help relevant practical researchers understand the current performance of academic models in various fields of healthcare, as well as the potential problems and future directions for implementing these scientific achievements.

In this era of rapid technological advancements, communication continues to evolve as new linguistic phenomena emerge. Among these is Arabizi, a hybrid form of Arabic that incorporates Latin characters and numbers to represent the spoken dialects of Arab communities. Arabizi is widely used on social media and allows people to communicate in an informal and dynamic way, but it poses significant challenges for machine translation due to its lack of formal structure and deeply embedded cultural nuances. This case study arises from a growing need to translate Arabizi for gisting purposes. It evaluates the capacity of different LLMs to decode and translate Arabizi, focusing on multiple Arabic dialects that have rarely been studied up until now. Using a combination of human evaluators and automatic metrics, this research project investigates the model's performance in translating Arabizi into both Modern Standard Arabic and English. Key questions explored include which dialects are translated most effectively and whether translations into English surpass those into Arabic.