The key-value (KV) cache in autoregressive transformers presents a significant bottleneck during inference, which restricts the context length capabilities of large language models (LLMs). While previous work analyzes the fundamental space complexity barriers in standard attention mechanism [Haris and Onak, 2025], our work generalizes the space complexity barriers result to tensor attention version. Our theoretical contributions rely on a novel reduction from communication complexity and deduce the memory lower bound for tensor-structured attention mechanisms when $d = \Omega(\log n)$. In the low dimensional regime where $d = o(\log n)$, we analyze the theoretical bounds of the space complexity as well. Overall, our work provides a theoretical foundation for us to understand the compression-expressivity tradeoff in tensor attention mechanisms and offers more perspectives in developing more memory-efficient transformer architectures.

The raster-ordered image token sequence exhibits a significant Euclidean distance between index-adjacent tokens at line breaks, making it unsuitable for autoregressive generation. To address this issue, this paper proposes Direction-Aware Diagonal Autoregressive Image Generation (DAR) method, which generates image tokens following a diagonal scanning order. The proposed diagonal scanning order ensures that tokens with adjacent indices remain in close proximity while enabling causal attention to gather information from a broader range of directions. Additionally, two direction-aware modules: 4D-RoPE and direction embeddings are introduced, enhancing the model's capability to handle frequent changes in generation direction. To leverage the representational capacity of the image tokenizer, we use its codebook as the image token embeddings. We propose models of varying scales, ranging from 485M to 2.0B. On the 256$\times$256 ImageNet benchmark, our DAR-XL (2.0B) outperforms all previous autoregressive image generators, achieving a state-of-the-art FID score of 1.37.

This evolution indicates an expansion from industrial uses into diverse fields, including healthcare [61], [59]. The core functionalities of digital twins include an accurate mirroring of their physical counterparts, capturing all associated processes in a data-driven manner, maintaining a continuous connection that synchronizes with the real-time state of their physical twins, and simulating physical behavior for predictive analysis [85]. In the context of healthcare, a novel extension of this technology manifests in the form of Human Digital Twins (HDTs), designed to provide a comprehensive digital mirror of individual patients. HDTs not only represent physical attributes but also integrate dynamic changes across molecular, physiological, and behavioral dimensions. This advancement is aligned with a shift toward personalized healthcare (PH) paradigms, enabling tailored treatment strategies based on a patient's unique health profile, thereby enhancing preventive, diagnostic, and therapeutic processes in clinical settings [44], [50]. The personalization aspect of HDTs underscores their potential to revolutionize healthcare by facilitating precise and individualized treatment plans that optimize patient outcomes [72]. Although the potential of digital twins in healthcare has garnered much attention, practical applications remain newly developing, with critical literature highlighting that many implementations are still in exploratory stages [59]. Notably, institutions like the IEEE Computer Society and Gartner recognize this technology as a pivotal component in the ongoing evolution of healthcare systems that emphasize both precision and personalization [31], [89].

Neural Audio Synthesis (NAS) models offer interactive musical control over high-quality, expressive audio generators. While these models can operate in real-time, they often suffer from high latency, making them unsuitable for intimate musical interaction. The impact of architectural choices in deep learning models on audio latency remains largely unexplored in the NAS literature. In this work, we investigate the sources of latency and jitter typically found in interactive NAS models. We then apply this analysis to the task of timbre transfer using RAVE, a convolutional variational autoencoder for audio waveforms introduced by Caillon et al. in 2021. Finally, we present an iterative design approach for optimizing latency. This culminates with a model we call BRAVE (Bravely Realtime Audio Variational autoEncoder), which is low-latency and exhibits better pitch and loudness replication while showing timbre modification capabilities similar to RAVE. We implement it in a specialized inference framework for low-latency, real-time inference and present a proof-of-concept audio plugin compatible with audio signals from musical instruments. We expect the challenges and guidelines described in this document to support NAS researchers in designing models for low-latency inference from the ground up, enriching the landscape of possibilities for musicians.

The increasing amount of pressure related to water and energy shortages has increased the urgency of cultivating individual conservation behaviors. While the concept of nudging, i.e., providing usage-based feedback, has shown promise in encouraging conservation behaviors, its efficacy is often constrained by the lack of targeted and actionable content. This study investigates the impact of the use of large language models (LLMs) to provide tailored conservation suggestions for conservation intentions and their rationale. Through a randomized controlled trial with 1,515 university participants, we compare three virtual nudging scenarios: no nudging, traditional nudging with usage statistics, and LLM-powered nudging with usage statistics and personalized conservation suggestions. The results of statistical analyses and causal forest modeling reveal that nudging led to an increase in conservation intentions among 86.9%-98.0% of the participants. LLM-powered nudging achieved a maximum increase of 18.0% in conservation intentions, surpassing traditional nudging by 88.6%. Furthermore, structural equation modeling results reveal that exposure to LLM-powered nudges enhances self-efficacy and outcome expectations while diminishing dependence on social norms, thereby increasing intrinsic motivation to conserve.

Music-to-music-video generation is a challenging task due to the intrinsic differences between the music and video modalities. The advent of powerful text-to-video diffusion models has opened a promising pathway for music-video (MV) generation by first addressing the music-to-MV description task and subsequently leveraging these models for video generation. In this study, we focus on the MV description generation task and propose a comprehensive pipeline encompassing training data construction and multimodal model fine-tuning. We fine-tune existing pre-trained multimodal models on our newly constructed music-to-MV description dataset based on the Music4All dataset, which integrates both musical and visual information. Our experimental results demonstrate that music representations can be effectively mapped to textual domains, enabling the generation of meaningful MV description directly from music inputs. We also identify key components in the dataset construction pipeline that critically impact the quality of MV description and highlight specific musical attributes that warrant greater focus for improved MV description generation.

Despite the ever-growing importance of online moderation, there has been no large-scale study evaluating the effectiveness of alternative moderation strategies. This is largely due to the lack of appropriate datasets, and the difficulty of getting human discussants, moderators, and evaluators involved in multiple experiments. In this paper, we propose a methodology for leveraging synthetic experiments performed exclusively by Large Language Models (LLMs) to initially bypass the need for human participation in experiments involving online moderation. We evaluate six LLM moderation configurations; two currently used real-life moderation strategies (guidelines issued for human moderators for online moderation and real-life facilitation), two baseline strategies (guidelines elicited for LLM alignment work, and LLM moderation with minimal prompting) a baseline with no moderator at all, as well as our own proposed strategy inspired by a Reinforcement Learning (RL) formulation of the problem. We find that our own moderation strategy significantly outperforms established moderation guidelines, as well as out-of-the-box LLM moderation. We also find that smaller LLMs, with less intensive instruction-tuning, can create more varied discussions than larger models. In order to run these experiments, we create and release an efficient, purpose-built, open-source Python framework, dubbed "SynDisco" to easily simulate hundreds of discussions using LLM user-agents and moderators. Additionally, we release the Virtual Moderation Dataset (VMD), a large dataset of LLM-generated and LLM-annotated discussions, generated by three families of open-source LLMs accompanied by an exploratory analysis of the dataset.

The necessity of achieving an effective balance between minimizing the losses associated with restricting human mobility and ensuring hospital capacity has gained significant attention in the aftermath of COVID-19. Reinforcement learning (RL)-based strategies for human mobility management have recently advanced in addressing the dynamic evolution of cities and epidemics; however, they still face challenges in achieving coordinated control at the township level and adapting to cities of varying scales. To address the above issues, we propose a multi-agent RL approach that achieves Pareto optimality in managing hospital capacity and human mobility (H2-MARL), applicable across cities of different scales. We first develop a township-level infection model with online-updatable parameters to simulate disease transmission and construct a city-wide dynamic spatiotemporal epidemic simulator. On this basis, H2-MARL is designed to treat each division as an agent, with a trade-off dual-objective reward function formulated and an experience replay buffer enriched with expert knowledge built. To evaluate the effectiveness of the model, we construct a township-level human mobility dataset containing over one billion records from four representative cities of varying scales. Extensive experiments demonstrate that H2-MARL has the optimal dual-objective trade-off capability, which can minimize hospital capacity strain while minimizing human mobility restriction loss. Meanwhile, the applicability of the proposed model to epidemic control in cities of varying scales is verified, which showcases its feasibility and versatility in practical applications.

Mechanistic interpretability has made great strides in identifying neural network features (e.g., directions in hidden activation space) that mediate concepts(e.g., the birth year of a person) and enable predictable manipulation. Distributed alignment search (DAS) leverages supervision from counterfactual data to learn concept features within hidden states, but DAS assumes we can afford to conduct a brute force search over potential feature locations. To address this, we present HyperDAS, a transformer-based hypernetwork architecture that (1) automatically locates the token-positions of the residual stream that a concept is realized in and (2) constructs features of those residual stream vectors for the concept. In experiments with Llama3-8B, HyperDAS achieves state-of-the-art performance on the RAVEL benchmark for disentangling concepts in hidden states. In addition, we review the design decisions we made to mitigate the concern that HyperDAS (like all powerful interpretabilty methods) might inject new information into the target model rather than faithfully interpreting it.

Agent-based modeling is indispensable for studying complex systems across many domains. However, existing simulation platforms exhibit two major issues: performance and modularity. Low performance prevents simulations with a large number of agents, increases development time, limits parameter exploration, and raises computing costs. Inflexible software designs motivate modelers to create their own tools, diverting valuable resources. This dissertation introduces a novel simulation platform called BioDynaMo and its significant improvement, TeraAgent, to alleviate these challenges via three major works. First, we lay the platform's foundation by defining abstractions, establishing software infrastructure, and implementing a multitude of features for agent-based modeling. We demonstrate BioDynaMo's modularity through use cases in neuroscience, epidemiology, and oncology. We validate these models and show the simplicity of adding new functionality with few lines of code. Second, we perform a rigorous performance analysis and identify challenges for shared-memory parallelism. Provided solutions include an optimized grid for neighbor searching, mechanisms to reduce the memory access latency, and exploiting domain knowledge to omit unnecessary work. These improvements yield up to three orders of magnitude speedups, enabling simulations of 1.7 billion agents on a single server. Third, we present TeraAgent, a distributed simulation engine that allows scaling out the computation of one simulation to multiple servers. We identify and address server communication bottlenecks and implement solutions for serialization and delta encoding to accelerate and reduce data transfer. TeraAgent can simulate 500 billion agents and scales to 84096 CPU cores. BioDynaMo has been widely adopted, including a prize-winning radiotherapy simulation recognized as a top 10 breakthrough in physics in 2024.