Africa
Niger Okays Armed Flights of US Drones
The U.S. official said armed drone flights could begin as early as next week or at least by the end of December. The memorandum of understanding limits the drones to defensive missions, the official said. The official was not authorized to discuss the matter publicly and so spoke on condition of anonymity.
15 gorgeous PC games that will punish your graphics card
I don't know how many times I've said "look at the draw distance" to people since Assassin's Creed: Origins ($60 on Amazon) released, but it's a lot. After "going back to their roots" with 2014's disastrous Assassin's Creed: Unity, Ubisoft has shaken up the series again and gone back to its...non-roots? Suffice it to say, Origins channels the spirit of Unity's predecessor, the acclaimed pirate-centric Black Flag. Origins heads to Ptolemaic Egypt instead of sailing the high seas, but the design is very similar, with an enormous map (the largest in the series) dotted with mid-size cities, small towns, oases, and so on. And if you look at screenshots, it might seem like a visual downgrade from Unity and the following year's Assassin's Creed: Syndicate.
Trans-allelic model for prediction of peptide:MHC-II interactions
Degoot, A. M., Chirove, Faraimunashe, Ndifon, Wilfred
Major histocompatibility complex class two (MHC-II) molecules are trans-membrane proteins and key components of the cellular immune system. Upon recognition of foreign peptides expressed on the MHC-II binding groove, helper T cells mount an immune response against invading pathogens. Therefore, mechanistic identification and knowledge of physico-chemical features that govern interactions between peptides and MHC-II molecules is useful for the design of effective epitope-based vaccines, as well as for understanding of immune responses. In this paper, we present a comprehensive trans-allelic prediction model, a generalized version of our previous biophysical model, that can predict peptide interactions for all three human MHC-II loci (HLA-DR, HLA-DP and HLA-DQ), using both peptide sequence data and structural information of MHC-II molecules. The advantage of this approach over other machine learning models is that it offers a simple and plausible physical explanation for peptide-MHC-II interactions. We train the model using a benchmark experimental dataset, and measure its predictive performance using novel data. Despite its relative simplicity, we find that the model has comparable performance to the state-of-the-art method. Focusing on the physical bases of peptide-MHC binding, we find support for previous theoretical predictions about the contributions of certain binding pockets to the binding energy. Additionally, we find that binding pockets P 4 and P 5 of HLA-DP, which were not previously considered as primary anchors, do make strong contributions to the binding energy. Together, the results indicate that our model can serve as a useful complement to alternative approaches to predicting peptide-MHC interactions.
AI Reinventing Banks and Banking
The evolution of financial systems has been a long but interesting journey characterised by sudden changes in underlying technology. Retail banking in Africa is far from where it should have been never followed the natural progression any ways. Artificial intelligence is here to reinvent the whole game of banking and transform this hundreds of years old business into new innovative, scalable, dynamic, micro service environment and efficient to the level where its incomparable. We're only at the beginning of this new age of computing which holds the potential to transform the entire working of a bank Financial payments and banking started in a very inefficient and traditional way which was slow but still acceptable to the customers due to the stage in the information age. There are lucrative but under-utilised banking opportunities in Africa and banks in the region need to step up and grasp these opportunities to succeed.
Here's how AI is subtly powering your life
Startups deploying AI can do everything from using drones for medical deliveries to helping lawyers prepare for court. Chen said his firm has invested in Zipline, an AI startup that uses drones to deliver blood to remote places such as western Rwanda. The service is critical to locations that are hard to access by land. "By the time a truck can get there, it may be too late," he said. Medical personnel in the field use an app to order blood by type.
Drones and smartphones help fight malaria in Tanzania
The fight against malaria has been improving, but there's still lots more work to do. For one thing, anti-larval sprays are both expensive and time-consuming -- you can't always afford to spray an entire area. Thankfully, a mix of technology is making that mosquito battle more practical. Wales' Aberystwyth University and Tanzania's Zanzibar Malaria Elimination Programme have partnered on an initiative that uses drones to survey malaria hot zones and identify the water-laden areas where malaria-carrying mosquitoes are likely to breed. An off-the-shelf drone (in this case, DJI's Phantom 3) can cover a large rice paddy in 20 minutes, and the data can be processed in the space of an afternoon.
Malaria Likelihood Prediction By Effectively Surveying Households Using Deep Reinforcement Learning
Rajpurkar, Pranav, Polamreddi, Vinaya, Balakrishnan, Anusha
We build a deep reinforcement learning (RL) agent that can predict the likelihood of an individual testing positive for malaria by asking questions about their household. The RL agent learns to determine which survey question to ask next and when to stop to make a prediction about their likelihood of malaria based on their responses hitherto. The agent incurs a small penalty for each question asked, and a large reward/penalty for making the correct/wrong prediction; it thus has to learn to balance the length of the survey with the accuracy of its final predictions. Our RL agent is a Deep Q-network that learns a policy directly from the responses to the questions, with an action defined for each possible survey question and for each possible prediction class. We focus on Kenya, where malaria is a massive health burden, and train the RL agent on a dataset of 6481 households from the Kenya Malaria Indicator Survey 2015. To investigate the importance of having survey questions be adaptive to responses, we compare our RL agent to a supervised learning (SL) baseline that fixes its set of survey questions a priori. We evaluate on prediction accuracy and on the number of survey questions asked on a holdout set and find that the RL agent is able to predict with 80% accuracy, using only 2.5 questions on average. In addition, the RL agent learns to survey adaptively to responses and is able to match the SL baseline in prediction accuracy while significantly reducing survey length.
When the robots take over; 4 new sci-fi reads
One major theme that's been running through science fiction recently is the rise of artificial intelligence and the impact that might have on humanity. As we continue to improve upon and refine machine learning, it seems inevitable that the development of a true AI will occur at some point. And consensus is that, once it does, humans will probably be in a bit of trouble. The four books on this list deal with common themes: intelligent robots that are contemplating the nature of their existence, and malevolent AI that seek the destruction of humanity (and the link between the two). When it comes to machine intelligence, we will reap what we sow, as these novels make evidently clear. Thirty years ago, humans lost the war with their servants, robots they created.