In recent years, automated radiology report generation has experienced significant growth. This paper introduces MRScore, an automatic evaluation metric tailored for radiology report generation by leveraging Large Language Models (LLMs). Conventional NLG (natural language generation) metrics like BLEU are inadequate for accurately assessing the generated radiology reports, as systematically demonstrated by our observations within this paper. To address this challenge, we collaborated with radiologists to develop a framework that guides LLMs for radiology report evaluation, ensuring alignment with human analysis. Our framework includes two key components: i) utilizing GPT to generate large amounts of training data, i.e., reports with different qualities, and ii) pairing GPT-generated reports as accepted and rejected samples and training LLMs to produce MRScore as the model reward. Our experiments demonstrate MRScore's higher correlation with human judgments and superior performance in model selection compared to traditional metrics. Our code and datasets will be available on GitHub. Keywords: Radiology Report Generation Evaluation metrics Large Language Models Reward Model.

The introduction of genome engineering technology has transformed biomedical research, making it possible to make precise changes to genetic information. However, creating an efficient gene-editing system requires a deep understanding of CRISPR technology, and the complex experimental systems under investigation. While Large Language Models (LLMs) have shown promise in various tasks, they often lack specific knowledge and struggle to accurately solve biological design problems. In this work, we introduce CRISPR-GPT, an LLM agent augmented with domain knowledge and external tools to automate and enhance the design process of CRISPR-based gene-editing experiments. CRISPR-GPT leverages the reasoning ability of LLMs to facilitate the process of selecting CRISPR systems, designing guide RNAs, recommending cellular delivery methods, drafting protocols, and designing validation experiments to confirm editing outcomes. We showcase the potential of CRISPR-GPT for assisting non-expert researchers with gene-editing experiments from scratch and validate the agent's effectiveness in a real-world use case. Furthermore, we explore the ethical and regulatory considerations associated with automated gene-editing design, highlighting the need for responsible and transparent use of these tools. Our work aims to bridge the gap between beginner biological researchers and CRISPR genome engineering techniques, and demonstrate the potential of LLM agents in facilitating complex biological discovery tasks.

The performance of the reward model (RM) is a critical factor in improving the effectiveness of the large language model (LLM) during alignment fine-tuning. There remain two challenges in RM training: 1) training the same RM using various categories of data may cause its generalization performance to suffer from multi-task disturbance, and 2) the human annotation consistency rate is generally only $60\%$ to $75\%$, causing training data to contain a lot of noise. To tackle these two challenges, we introduced the idea of Mixture-of-Experts (MoE) into the field of RM for the first time. We propose the Double-Layer MoE RM (DMoERM). The outer layer MoE is a sparse model. After classifying an input into task categories, we route it to the corresponding inner layer task-specific model. The inner layer MoE is a dense model. We decompose the specific task into multiple capability dimensions and individually fine-tune a LoRA expert on each one. Their outputs are then synthesized by an MLP to compute the final rewards. To minimize costs, we call a public LLM API to obtain the capability preference labels. The validation on manually labeled datasets confirms that our model attains superior consistency with human preference and outstrips advanced generative approaches. Meanwhile, through BoN sampling and RL experiments, we demonstrate that our model outperforms state-of-the-art ensemble methods of RM and mitigates the overoptimization problem. Our code and dataset are available at: https://github.com/quanshr/DMoERM-v1.

Perceptions of hate can vary greatly across cultural contexts. Hate speech (HS) datasets, however, have traditionally been developed by language. This hides potential cultural biases, as one language may be spoken in different countries home to different cultures. In this work, we evaluate cultural bias in HS datasets by leveraging two interrelated cultural proxies: language and geography. We conduct a systematic survey of HS datasets in eight languages and confirm past findings on their English-language bias, but also show that this bias has been steadily decreasing in the past few years. For three geographically-widespread languages -- English, Arabic and Spanish -- we then leverage geographical metadata from tweets to approximate geo-cultural contexts by pairing language and country information. We find that HS datasets for these languages exhibit a strong geo-cultural bias, largely overrepresenting a handful of countries (e.g., US and UK for English) relative to their prominence in both the broader social media population and the general population speaking these languages. Based on these findings, we formulate recommendations for the creation of future HS datasets.

Automatic Speech Understanding (ASU) aims at human-like speech interpretation, providing nuanced intent, emotion, sentiment, and content understanding from speech and language (text) content conveyed in speech. Typically, training a robust ASU model relies heavily on acquiring large-scale, high-quality speech and associated transcriptions. However, it is often challenging to collect or use speech data for training ASU due to concerns such as privacy. To approach this setting of enabling ASU when speech (audio) modality is missing, we propose TI-ASU, using a pre-trained text-to-speech model to impute the missing speech. We report extensive experiments evaluating TI-ASU on various missing scales, both multi- and single-modality settings, and the use of LLMs. Our findings show that TI-ASU yields substantial benefits to improve ASU in scenarios where even up to 95% of training speech is missing. Moreover, we show that TI-ASU is adaptive to dropout training, improving model robustness in addressing missing speech during inference.

Iranian-backed Houthis rebels have claimed responsibility for a U.S. MQ-9 Reaper drone crash off the coast of Yemen on Thursday, Fox News confirmed on Friday. Thursday's crash is the fourth remotely piloted drone brought down by Iranian-proxy groups since November, costing the U.S. government upwards of 120 million. It is also the third time Houthi rebels have brought down a U.S. MQ-9 drone. Remotely piloted MQ-9 Reaper drones cost around 30 million each. Last fall, the Houthis released video of a reaper drone the rebels shot down on Nov. 8, one day after Hamas' unprovoked attack on Israel.

WhatsApp, the popular global messaging platform owned by Meta, has rolled out new features including a different way to log in and an artificial intelligence assistant in the app. Whatsapp said on X, formerly Twitter, on April 24 that this feature was "a more secure way to login." It also avoids any potential challenges in receiving an SMS to log in, with the company adding: "traveling? The messaging app already launched passkeys for Android users in October, as demonstrated by a post shared on Threads, another Meta social media platform. People with Pixel 8 and 8 Pro Google phones can now also use Face Unlock, instead of their fingerprint or PIN, to unlock and view messages on WhatsApp, as reported by 9to5Google.

Presently, with the assistance of advanced LLM application development frameworks, more and more LLM-powered applications can effortlessly augment the LLMs' knowledge with external content using the retrieval augmented generation (RAG) technique. However, these frameworks' designs do not have sufficient consideration of the risk of external content, thereby allowing attackers to undermine the applications developed with these frameworks. In this paper, we reveal a new threat to LLM-powered applications, termed retrieval poisoning, where attackers can guide the application to yield malicious responses during the RAG process. Specifically, through the analysis of LLM application frameworks, attackers can craft documents visually indistinguishable from benign ones. Despite the documents providing correct information, once they are used as reference sources for RAG, the application is misled into generating incorrect responses. Our preliminary experiments indicate that attackers can mislead LLMs with an 88.33\% success rate, and achieve a 66.67\% success rate in the real-world application, demonstrating the potential impact of retrieval poisoning.

The rapid evolution of Natural Language Processing (NLP) has favored major languages such as English, leaving a significant gap for many others due to limited resources. This is especially evident in the context of data annotation, a task whose importance cannot be underestimated, but which is time-consuming and costly. Thus, any dataset for resource-poor languages is precious, in particular when it is task-specific. Here, we explore the feasibility of repurposing existing datasets for a new NLP task: we repurposed the Belebele dataset (Bandarkar et al., 2023), which was designed for multiple-choice question answering (MCQA), to enable extractive QA (EQA) in the style of machine reading comprehension. We present annotation guidelines and a parallel EQA dataset for English and Modern Standard Arabic (MSA). We also present QA evaluation results for several monolingual and cross-lingual QA pairs including English, MSA, and five Arabic dialects. Our aim is to enable others to adapt our approach for the 120+ other language variants in Belebele, many of which are deemed under-resourced. We also conduct a thorough analysis and share our insights from the process, which we hope will contribute to a deeper understanding of the challenges and the opportunities associated with task reformulation in NLP research.

In this paper, we propose a new dataset distillation method that considers balancing global structure and local details when distilling the information from a large dataset into a generative model. Dataset distillation has been proposed to reduce the size of the required dataset when training models. The conventional dataset distillation methods face the problem of long redeployment time and poor cross-architecture performance. Moreover, previous methods focused too much on the high-level semantic attributes between the synthetic dataset and the original dataset while ignoring the local features such as texture and shape. Based on the above understanding, we propose a new method for distilling the original image dataset into a generative model. Our method involves using a conditional generative adversarial network to generate the distilled dataset. Subsequently, we ensure balancing global structure and local details in the distillation process, continuously optimizing the generator for more information-dense dataset generation.