Researchers have been using artificial intelligence to study how the microbiome interacts with the human system to improve vaccine response. A team of researchers at Iowa State University, US, are employing innovative artificial intelligence (AI) to investigate how the microbiome interacts with the immune system. The team, led by Dr Gregory Phillips, said that they are focusing on gut bacteria that have adapted to live in the human digestive system to improve vaccine response. We want to go beyond associations to get causes, something in the microbiota that influences the host whereby vaccines can be improved" The team are leading trials in mice monitoring changes in microbiota spurred by vaccine delivery and immune response. As the interactions they will be observing are so complex, the team have collaborated with Indiana University, US, to apply machine learning to find patterns in vast amounts of data.