Recent knowledge editing methods have primarily focused on modifying structured knowledge in large language models, heavily relying on the assumption that structured knowledge is stored as key-value pairs locally in MLP layers or specific neurons. However, this task setting overlooks the fact that a significant portion of real-world knowledge is stored in an unstructured format, characterized by long-form content, noise, and a complex yet comprehensive nature. The "knowledge locating" and "term-driven optimization" techniques conducted from the assumption used in previous methods (e.g., MEMIT) are ill-suited for unstructured knowledge. To address these challenges, we propose a novel unstructured knowledge editing method, namely UnKE, which extends previous assumptions in the layer dimension and token dimension. Firstly, in the layer dimension, we discard the "knowledge locating" step and treat first few layers as the key, which expand knowledge storage through layers to break the "knowledge stored locally" assumption. Next, we replace "term-driven optimization" with "cause-driven optimization" across all inputted tokens in the token dimension, directly optimizing the last layer of the key generator to perform editing to generate the required key vectors. By utilizing key-value pairs at the layer level, UnKE effectively represents and edits complex and comprehensive unstructured knowledge, leveraging the potential of both the MLP and attention layers. Results on newly proposed unstructure knowledge editing dataset (UnKEBench) and traditional structured datasets demonstrate that UnKE achieves remarkable performance, surpassing strong baselines.

In recent years, AI models that mine intrinsic patterns from molecular structures and protein sequences have shown promise in accelerating drug discovery. However, these methods partly lag behind real-world pharmaceutical approaches of human experts that additionally grasp structured knowledge from knowledge bases and unstructured knowledge from biomedical literature. To bridge this gap, we propose KEDD, a unified, end-to-end, and multimodal deep learning framework that optimally incorporates both structured and unstructured knowledge for vast AI drug discovery tasks. The framework first extracts underlying characteristics from heterogeneous inputs, and then applies multimodal fusion for accurate prediction. To mitigate the problem of missing modalities, we leverage multi-head sparse attention and a modality masking mechanism to extract relevant information robustly. Benefiting from integrated knowledge, our framework achieves a deeper understanding of molecule entities, brings significant improvements over state-of-the-art methods on a wide range of tasks and benchmarks, and reveals its promising potential in assisting real-world drug discovery.

Pre-trained language models (PLMs) demonstrate excellent abilities to understand texts in the generic domain while struggling in a specific domain. Although continued pre-training on a large domain-specific corpus is effective, it is costly to tune all the parameters on the domain. In this paper, we investigate whether we can adapt PLMs both effectively and efficiently by only tuning a few parameters. Specifically, we decouple the feed-forward networks (FFNs) of the Transformer architecture into two parts: the original pre-trained FFNs to maintain the old-domain knowledge and our novel domain-specific adapters to inject domain-specific knowledge in parallel. Then we adopt a mixture-of-adapters gate to fuse the knowledge from different domain adapters dynamically. Our proposed Mixture-of-Domain-Adapters (MixDA) employs a two-stage adapter-tuning strategy that leverages both unlabeled data and labeled data to help the domain adaptation: i) domain-specific adapter on unlabeled data; followed by ii) the task-specific adapter on labeled data. MixDA can be seamlessly plugged into the pretraining-finetuning paradigm and our experiments demonstrate that MixDA achieves superior performance on in-domain tasks (GLUE), out-of-domain tasks (ChemProt, RCT, IMDB, Amazon), and knowledge-intensive tasks (KILT). Further analyses demonstrate the reliability, scalability, and efficiency of our method. The code is available at https://github.com/Amano-Aki/Mixture-of-Domain-Adapters.

Although named entity recognition (NER) helps us to extract domain-specific entities from text (e.g., artists in the music domain), it is costly to create a large amount of training data or a structured knowledge base to perform accurate NER in the target domain. Here, we propose self-adaptive NER, which retrieves external knowledge from unstructured text to learn the usages of entities that have not been learned well. To retrieve useful knowledge for NER, we design an effective two-stage model that retrieves unstructured knowledge using uncertain entities as queries. Our model predicts the entities in the input and then finds those of which the prediction is not confident. Then, it retrieves knowledge by using these uncertain entities as queries and concatenates the retrieved text to the original input to revise the prediction. Experiments on CrossNER datasets demonstrated that our model outperforms strong baselines by 2.35 points in F1 metric.

Recent research demonstrates that external knowledge injection can advance pre-trained language models (PLMs) in a variety of downstream NLP tasks. However, existing knowledge injection methods are either applicable to structured knowledge or unstructured knowledge, lacking a unified usage. In this paper, we propose a UNified knowledge inTERface, UNTER, to provide a unified perspective to exploit both structured knowledge and unstructured knowledge. In UNTER, we adopt the decoder as a unified knowledge interface, aligning span representations obtained from the encoder with their corresponding knowledge. This approach enables the encoder to uniformly invoke span-related knowledge from its parameters for downstream applications. Experimental results show that, with both forms of knowledge injected, UNTER gains continuous improvements on a series of knowledge-driven NLP tasks, including entity typing, named entity recognition and relation extraction, especially in low-resource scenarios.

Inferring the substitutable and complementary products for a given product is an essential and fundamental concern for the recommender system. To achieve this, existing approaches take advantage of the knowledge graphs to learn more evidences for inference, whereas they often suffer from invalid reasoning for lack of elegant decision making strategies. Therefore, we propose a novel Knowledge-Aware Path Reasoning (KAPR) model which leverages the dynamic policy network to make explicit reasoning over knowledge graphs, for inferring the substitutable and complementary relationships. Our contributions can be highlighted as three aspects. Firstly, we model this inference scenario as a Markov Decision Process in order to accomplish a knowledge-aware path reasoning over knowledge graphs. Secondly,we integrate both structured and unstructured knowledge to provide adequate evidences for making accurate decision-making. Thirdly, we evaluate our model on a series of real-world datasets, achieving competitive performance compared with state-of-the-art approaches. Our code is released on https://gitee.com/yangzijing flower/kapr/tree/master.