Over the past decade, generative models have achieved significant success in enhancement fundus images.However, the evaluation of these models still presents a considerable challenge. A comprehensive evaluation benchmark for fundus image enhancement is indispensable for three main reasons: 1) The existing denoising metrics (e.g., PSNR, SSIM) are hardly to extend to downstream real-world clinical research (e.g., Vessel morphology consistency). 2) There is a lack of comprehensive evaluation for both paired and unpaired enhancement methods, along with the need for expert protocols to accurately assess clinical value. 3) An ideal evaluation system should provide insights to inform future developments of fundus image enhancement. To this end, we propose a novel comprehensive benchmark, EyeBench, to provide insights that align enhancement models with clinical needs, offering a foundation for future work to improve the clinical relevance and applicability of generative models for fundus image enhancement. EyeBench has three appealing properties: 1) multi-dimensional clinical alignment downstream evaluation: In addition to evaluating the enhancement task, we provide several clinically significant downstream tasks for fundus images, including vessel segmentation, DR grading, denoising generalization, and lesion segmentation. 2) Medical expert-guided evaluation design: We introduce a novel dataset that promote comprehensive and fair comparisons between paired and unpaired methods and includes a manual evaluation protocol by medical experts. 3) Valuable insights: Our benchmark study provides a comprehensive and rigorous evaluation of existing methods across different downstream tasks, assisting medical experts in making informed choices. Additionally, we offer further analysis of the challenges faced by existing methods. The code is available at \url{https://github.com/Retinal-Research/EyeBench}

Optical remote sensing and Synthetic Aperture Radar(SAR) remote sensing are crucial for earth observation, offering complementary capabilities. While optical sensors provide high-quality images, they are limited by weather and lighting conditions. In contrast, SAR sensors can operate effectively under adverse conditions. This letter proposes a GAN-based SAR-to-optical image translation method named Seg-CycleGAN, designed to enhance the accuracy of ship target translation by leveraging semantic information from a pre-trained semantic segmentation model. Our method utilizes the downstream task of ship target semantic segmentation to guide the training of image translation network, improving the quality of output Optical-styled images. The potential of foundation-model-annotated datasets in SAR-to-optical translation tasks is revealed. This work suggests broader research and applications for downstream-task-guided frameworks. The code will be available at https://github.com/NPULHH/