Optimizing complex and high-dimensional black-box functions is ubiquitous in science and engineering fields. Unfortunately, the online evaluation of these functions is restricted due to time and safety constraints in most cases. In offline model-based optimization (MBO), we aim to find a design that maximizes the target function using only a pre-existing offline dataset. While prior methods consider forward or inverse approaches to address the problem, these approaches are limited by conservatism and the difficulty of learning highly multi-modal mappings. Recently, there has been an emerging paradigm of learning to improve solutions with synthetic trajectories constructed from the offline dataset.

Adaptive treatment strategies (ATS) are sequential decision-making processes that enable personalized care by dynamically adjusting treatment decisions in response to evolving patient symptoms. While reinforcement learning (RL) offers a promising approach for optimizing ATS, its conventional online trial-and-error learning mechanism is not permissible in clinical settings due to risks of harm to patients. Offline RL tackles this limitation by learning policies exclusively from historical treatment data, but its performance is often constrained by data scarcity-a pervasive challenge in clinical domains. To overcome this, we propose Treatment Stitching (TreatStitch), a novel data augmentation framework that generates clinically valid treatment trajectories by intelligently stitching segments from existing treatment data. Specifically, TreatStitch identifies similar intermediate patient states across different trajectories and stitches their respective segments. Even when intermediate states are too dissimilar to stitch directly, TreatStitch leverages the Schrödinger bridge method to generate smooth and energy-efficient bridging trajectories that connect dissimilar states. By augmenting these synthetic trajectories into the original dataset, offline RL can learn from a more diverse dataset, thereby improving its ability to optimize ATS. Extensive experiments across multiple treatment datasets demonstrate the effectiveness of TreatStitch in enhancing offline RL performance. Furthermore, we provide a theoretical justification showing that TreatStitch maintains clinical validity by avoiding out-of-distribution transitions.

The analysis results on the synthetic dataset of Xi'an city fully validate the feasibility of the proposed

Optimizing complex and high-dimensional black-box functions is ubiquitous in science and engineering fields. Unfortunately, the online evaluation of these functions is restricted due to time and safety constraints in most cases. In offline model-based optimization (MBO), we aim to find a design that maximizes the target function using only a pre-existing offline dataset. While prior methods consider forward or inverse approaches to address the problem, these approaches are limited by conservatism and the difficulty of learning highly multi-modal mappings. Recently, there has been an emerging paradigm of learning to improve solutions with synthetic trajectories constructed from the offline dataset.

Reinforcement learning has been shown to improve the performance of large language models. However, traditional approaches like RLHF or RLAIF treat the problem as single-step. As focus shifts toward more complex reasoning and agentic tasks, language models must take multiple steps of text generation, reasoning and environment interaction before generating a solution. We propose a synthetic data generation and RL methodology targeting multi-step optimization scenarios. This approach, called Step-Wise Reinforcement Learning (SWiRL), iteratively generates multi-step reasoning and tool use data, and then learns from that data. It employs a simple step-wise decomposition that breaks each multi-step trajectory into multiple sub-trajectories corresponding to each action by the original model. It then applies synthetic data filtering and RL optimization on these sub-trajectories. We evaluated SWiRL on a number of multi-step tool use, question answering, and mathematical reasoning tasks. Our experiments show that SWiRL outperforms baseline approaches by 21.5%, 12.3%, 14.8%, 11.1%, and 15.3% in relative accuracy on GSM8K, HotPotQA, CofCA, MuSiQue, and BeerQA, respectively. Excitingly, the approach exhibits generalization across tasks: for example, training only on HotPotQA (text question-answering) improves zero-shot performance on GSM8K (a math dataset) by a relative 16.9%.

In modern air traffic management, generating synthetic flight trajectories has emerged as a promising solution for addressing data scarcity, protecting sensitive information, and supporting large-scale analyses. In this paper, we propose a novel method for trajectory synthesis by adapting the Time-Based Vector Quantized Variational Autoencoder (TimeVQVAE). Our approach leverages time-frequency domain processing, vector quantization, and transformer-based priors to capture both global and local dynamics in flight data. By discretizing the latent space and integrating transformer priors, the model learns long-range spatiotemporal dependencies and preserves coherence across entire flight paths. We evaluate the adapted TimeVQVAE using an extensive suite of quality, statistical, and distributional metrics, as well as a flyability assessment conducted in an open-source air traffic simulator. Results indicate that TimeVQVAE outperforms a temporal convolutional VAE baseline, generating synthetic trajectories that mirror real flight data in terms of spatial accuracy, temporal consistency, and statistical properties. Furthermore, the simulator-based assessment shows that most generated trajectories maintain operational feasibility, although occasional outliers underscore the potential need for additional domain-specific constraints. Overall, our findings underscore the importance of multi-scale representation learning for capturing complex flight behaviors and demonstrate the promise of TimeVQVAE in producing representative synthetic trajectories for downstream tasks such as model training, airspace design, and air traffic forecasting.

Accurately predicting pedestrian trajectories is crucial in applications such as autonomous driving or service robotics, to name a few. Deep generative models achieve top performance in this task, assuming enough labelled trajectories are available for training. To this end, large amounts of synthetically generated, labelled trajectories exist (e.g., generated by video games). However, such trajectories are not meant to represent pedestrian motion realistically and are ineffective at training a predictive model. We propose a method and an architecture to augment synthetic trajectories at training time and with an adversarial approach. We show that trajectory augmentation at training time unleashes significant gains when a state-of-the-art generative model is evaluated over real-world trajectories.

User mobility modeling serves a crucial role in analysis and optimization of contemporary wireless networks. Typical stochastic mobility models, e.g., random waypoint model and Gauss Markov model, can hardly capture the distribution characteristics of users within real-world areas. State-of-the-art trace-based mobility models and existing learning-based trajectory generation methods, however, are frequently constrained by the inaccessibility of substantial real trajectories due to privacy concerns. In this paper, we harness the intrinsic correlation between street maps and trajectories and develop a novel zero-shot trajectory generation method, named Map2Traj, by exploiting the diffusion model. We incorporate street maps as a condition to consistently pilot the denoising process and train our model on diverse sets of real trajectories from various regions in Xi'an, China, and their corresponding street maps. With solely the street map of an unobserved area, Map2Traj generates synthetic trajectories that not only closely resemble the real-world mobility pattern but also offer comparable efficacy. Extensive experiments validate the efficacy of our proposed method on zero-shot trajectory generation tasks in terms of both trajectory and distribution similarities. In addition, a case study of employing Map2Traj in wireless network optimization is presented to validate its efficacy for downstream applications.

Generating human mobility trajectories is of great importance to solve the lack of large-scale trajectory data in numerous applications, which is caused by privacy concerns. However, existing mobility trajectory generation methods still require real-world human trajectories centrally collected as the training data, where there exists an inescapable risk of privacy leakage. To overcome this limitation, in this paper, we propose PateGail, a privacy-preserving imitation learning model to generate mobility trajectories, which utilizes the powerful generative adversary imitation learning model to simulate the decision-making process of humans. Further, in order to protect user privacy, we train this model collectively based on decentralized mobility data stored in user devices, where personal discriminators are trained locally to distinguish and reward the real and generated human trajectories. In the training process, only the generated trajectories and their rewards obtained based on personal discriminators are shared between the server and devices, whose privacy is further preserved by our proposed perturbation mechanisms with theoretical proof to satisfy differential privacy. Further, to better model the human decision-making process, we propose a novel aggregation mechanism of the rewards obtained from personal discriminators. We theoretically prove that under the reward obtained based on the aggregation mechanism, our proposed model maximizes the lower bound of the discounted total rewards of users. Extensive experiments show that the trajectories generated by our model are able to resemble real-world trajectories in terms of five key statistical metrics, outperforming state-of-the-art algorithms by over 48.03%. Furthermore, we demonstrate that the synthetic trajectories are able to efficiently support practical applications, including mobility prediction and location recommendation.