sleep state
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On the relations of LFPs & Neural Spike Trains
David E. Carlson, Jana Schaich Borg, Kafui Dzirasa, Lawrence Carin
One of the goals of neuroscience is to identify neural networks that correlate with important behaviors, environments, or genotypes. This work proposes a strategy for identifying neural networks characterized by time-and frequency-dependent connectivity patterns, using convolutional dictionary learning that links spike-train data to local field potentials (LFPs) across multiple areas of the brain. Analytical contributions are: ( i) modeling dynamic relationships between LFPs and spikes; ( ii) describing the relationships between spikes and LFPs, by analyzing the ability to predict LFP data from one region based on spiking information from across the brain; and ( iii) development of a clustering methodology that allows inference of similarities in neurons from multiple regions. Results are based on data sets in which spike and LFP data are recorded simultaneously from up to 16 brain regions in a mouse.
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FetalSleepNet: A Transfer Learning Framework with Spectral Equalisation Domain Adaptation for Fetal Sleep Stage Classification
Tang, Weitao, Vargas-Calixto, Johann, Katebi, Nasim, Tran, Nhi, Kelly, Sharmony B., Clifford, Gari D., Galinsky, Robert, Marzbanrad, Faezeh
Abstract--Introduction: This study presents FetalSleepNet, the first published deep learning approach to classifying sleep states from the ovine electroencephalogram (EEG). Fetal EEG is complex to acquire and difficult and laborious to interpret consistently. However, accurate sleep stage classification may aid in the early detection of abnormal brain maturation associated with pregnancy complications (e.g. Methods: EEG electrodes were secured onto the ovine dura over the parietal cortices of 24 late-gestation fetal sheep. A lightweight deep neural network originally developed for adult EEG sleep staging was trained on the ovine EEG using transfer learning from adult EEG. A spectral equalisation-based domain adaptation strategy was used to reduce cross-domain mismatch. Results: We demonstrated that while direct transfer performed poorly, full fine-tuning combined with spectral equalisation achieved the best overall performance (accuracy: 86.6%, macro F1-score: 62.5), outperforming baseline models. Conclusions: T o the best of our knowledge, FetalSleepNet is the first deep learning framework specifically developed for automated sleep staging from the fetal EEG. Beyond the laboratory, the EEG-based sleep stage classifier functions as a label engine, enabling large-scale weak/semi-supervised labeling and distillation to facilitate training on less invasive signals that can be acquired in the clinic, such as Doppler Ultrasound or electrocardiogram data. FetalSleepNet's lightweight design makes it well suited for deployment in low-power, real-time, and wearable fetal monitoring systems. LEEP state patterns reflect fetal neurophysiological function and development [1], and are clinically relevant for detecting abnormal neurodevelopment, which may result from conditions such as chronic hypoxia, infection or hypertensive disorders of pregnancy (HDP) [2]-[4]. J. V argas-Calixto, N. Katebi, and G. D. Clifford are with the Department of Biomedical Informatics, Emory University, Atlanta, USA. Nhi Tran, R. Galinsky and S. B. Kelly are with the Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia. G. D. Clifford is also with the Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, USA.
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On the relations of LFPs & Neural Spike Trains
David E. Carlson, Jana Schaich Borg, Kafui Dzirasa, Lawrence Carin
One of the goals of neuroscience is to identify neural networks that correlate with important behaviors, environments, or genotypes. This work proposes a strategy for identifying neural networks characterized by time-and frequency-dependent connectivity patterns, using convolutional dictionary learning that links spike-train data to local field potentials (LFPs) across multiple areas of the brain. Analytical contributions are: (i) modeling dynamic relationships between LFPs and spikes; (ii) describing the relationships between spikes and LFPs, by analyzing the ability to predict LFP data from one region based on spiking information from across the brain; and (iii) development of a clustering methodology that allows inference of similarities in neurons from multiple regions. Results are based on data sets in which spike and LFP data are recorded simultaneously from up to 16 brain regions in a mouse.
On the Relationship Between LFP & Spiking Data David E. Carlson, Jana Schaich Borg
One of the goals of neuroscience is to identify neural networks that correlate with important behaviors, environments, or genotypes. This work proposes a strategy for identifying neural networks characterized by time-and frequency-dependent connectivity patterns, using convolutional dictionary learning that links spike-train data to local field potentials (LFPs) across multiple areas of the brain. Analytical contributions are: (i) modeling dynamic relationships between LFPs and spikes; (ii) describing the relationships between spikes and LFPs, by analyzing the ability to predict LFP data from one region based on spiking information from across the brain; and (iii) development of a clustering methodology that allows inference of similarities in neurons from multiple regions. Results are based on data sets in which spike and LFP data are recorded simultaneously from up to 16 brain regions in a mouse.
Real-life Inception headband lets you control your dreams - but experts fear zapping the brain with 2,000 device could hinder cognitive abilities during waking hours
An AI tech startup wants you to trade in regular dreams for a headband that lets you control your nighttime wanderings in a lucid dreamlike state. Prophetic is releasing the 2,000 Halo AI headband in 2025, which will give wearers unparalleled control over their dreams that could help users grapple with existing problems they're facing in their waking lives. The headband uses electroencephalography (EEG), which records electrical activity in the brain, and functional magnetic resonance imaging (fMRI) which measures brain activity by measuring the blood flow. However, experts aren't yet sure what the long-term effects could be and warn that using high-frequency sounds to zap your brain, could hinder our cognitive ability to process short-term memories. 'We are very rarely lucid in our dreams.
Annotating sleep states in children from wrist-worn accelerometer data using Machine Learning
Ram, Ashwin, S., Sundar Sripada V., Keshari, Shuvam, Jiang, Zizhe
Sleep detection and annotation are crucial for researchers to understand sleep patterns, especially in children. With modern wrist-worn watches comprising built-in accelerometers, sleep logs can be collected. However, the annotation of these logs into distinct sleep events: onset and wakeup, proves to be challenging. These annotations must be automated, precise, and scalable. We propose to model the accelerometer data using different machine learning (ML) techniques such as support vectors, boosting, ensemble methods, and more complex approaches involving LSTMs and Region-based CNNs. Later, we aim to evaluate these approaches using the Event Detection Average Precision (EDAP) score (similar to the IOU metric) to eventually compare the predictive power and model performance.
SleepMore: Inferring Sleep Duration at Scale via Multi-Device WiFi Sensing
Zakaria, Camellia, Yilmaz, Gizem, Mammen, Priyanka, Chee, Michael, Shenoy, Prashant, Balan, Rajesh
The availability of commercial wearable trackers equipped with features to monitor sleep duration and quality has enabled more useful sleep health monitoring applications and analyses. However, much research has reported the challenge of long-term user retention in sleep monitoring through these modalities. Since modern Internet users own multiple mobile devices, our work explores the possibility of employing ubiquitous mobile devices and passive WiFi sensing techniques to predict sleep duration as the fundamental measure for complementing long-term sleep monitoring initiatives. In this paper, we propose SleepMore, an accurate and easy-to-deploy sleep-tracking approach based on machine learning over the user's WiFi network activity. It first employs a semi-personalized random forest model with an infinitesimal jackknife variance estimation method to classify a user's network activity behavior into sleep and awake states per minute granularity. Through a moving average technique, the system uses these state sequences to estimate the user's nocturnal sleep period and its uncertainty rate. Uncertainty quantification enables SleepMore to overcome the impact of noisy WiFi data that can yield large prediction errors. We validate SleepMore using data from a month-long user study involving 46 college students and draw comparisons with the Oura Ring wearable. Beyond the college campus, we evaluate SleepMore on non-student users of different housing profiles. Our results demonstrate that SleepMore produces statistically indistinguishable sleep statistics from the Oura ring baseline for predictions made within a 5% uncertainty rate. These errors range between 15-28 minutes for determining sleep time and 7-29 minutes for determining wake time, proving statistically significant improvements over prior work. Our in-depth analysis explains the sources of errors.
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- Health & Medicine > Therapeutic Area > Sleep (1.00)
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Development of Sleep State Trend (SST), a bedside measure of neonatal sleep state fluctuations based on single EEG channels
Moghadam, Saeed Montazeri, Nevalainen, Päivi, Stevenson, Nathan J., Vanhatalo, Sampsa
Objective: To develop and validate an automated method for bedside monitoring of sleep state fluctuations in neonatal intensive care units. Methods: A deep learning -based algorithm was designed and trained using 53 EEG recordings from a long-term (a)EEG monitoring in 30 near-term neonates. The results were validated using an external dataset from 30 polysomnography recordings. In addition to training and validating a single EEG channel quiet sleep detector, we constructed Sleep State Trend (SST), a bedside-ready means for visualizing classifier outputs. Results: The accuracy of quiet sleep detection in the training data was 90%, and the accuracy was comparable (85-86%) in all bipolar derivations available from the 4-electrode recordings. The algorithm generalized well to an external dataset, showing 81% overall accuracy despite different signal derivations. SST allowed an intuitive, clear visualization of the classifier output. Conclusions: Fluctuations in sleep states can be detected at high fidelity from a single EEG channel, and the results can be visualized as a transparent and intuitive trend in the bedside monitors. Significance: The Sleep State Trend (SST) may provide caregivers a real-time view of sleep state fluctuations and its cyclicity.
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