Imagine the lips forming the Mona Lisa's famous smile were to part, and she began "speaking" to you. This is not some sci-fi fantasy or a 3D face animation, it's an effect achieved by researchers from Samsung AI lab and Skolkovo Institute of Science and Technology, who used adversarial learning to generate a photorealistic talking head model. AI techniques have already been used to generate realistic video of people like former US President Barack Obama and movie star Scarlett Johansson, enabled in large part by the abundance of available visual data on these individuals. The new research however shows it is also possible to generate realistic content when source images are rare. Researchers leveraged their Few-Shot Adversarial Learning technique on one of the most widely recognized humans in history known through a single image: Lisa Gherardini, the subject of Leonardo da Vinci's classic 16th century portrait.