This work introduces the Monolithic Unit (MU), an actuator-lattice-sensor building block for soft robotics. The MU integrates pneumatic actuation, a compliant lattice envelope, and candidate sites for optical waveguide sensing into a single printed body. In order to study reproducibility and scalability, a parametric design framework establishes deterministic rules linking actuator chamber dimensions to lattice unit cell size. Experimental homogenization of lattice specimens provides effective material properties for finite element simulation. Within this simulation environment, sensor placement is treated as a discrete optimization problem, where a finite set of candidate waveguide paths derived from lattice nodes is evaluated by introducing local stiffening, and the configuration minimizing deviation from baseline mechanical response is selected. Optimized models are fabricated and experimentally characterized, validating the preservation of mechanical performance while enabling embedded sensing. The workflow is further extended to scaled units and a two-finger gripper, demonstrating generality of the MU concept. This approach advances monolithic soft robotic design by combining reproducible co-design rules with simulation-informed sensor integration.

To reproduce natural standing-up motion, recent studies have emphasized the importance of coordination between the assisting robot and the human. However, many non-wearable assistive devices have struggled to replicate natural motion trajectories. While wearable devices offer better coordination with the human body, they present challenges in completely isolating mechanical and electrical hazards. To address this, we developed a novel standing-assist robot that integrates features of both wearable and non-wearable systems, aiming to achieve high coordination while maintaining safety. The device employs a four-link mechanism aligned with the human joint structure, designed to reproduce the S-shaped trajectory of the hip and the arc trajectory of the knee during natural standing-up motion. Subject-specific trajectory data were obtained using a gyroscope, and the link lengths were determined to drive the seat along the optimal path. A feedforward speed control using a stepping motor was implemented, and the reproducibility of the trajectory was evaluated based on the geometric constraints of the mechanism. A load-bearing experiment with weights fixed to the seat was conducted to assess the trajectory accuracy under different conditions. Results showed that the reproduction errors for the hip and knee trajectories remained within approximately 4 percent of the seat's total displacement, demonstrating high fidelity to the target paths. In addition, durability testing, thermal safety evaluation, and risk assessment confirmed the reliability and safety of the system for indoor use. These findings suggest that the proposed design offers a promising approach for developing assistive technologies that adapt to individual physical characteristics, with potential applications in elderly care and rehabilitation.

Current studies on human locomotion focus mainly on solid ground walking conditions. In this paper, we present a biomechanic comparison of human walking locomotion on solid ground and sand. A novel dataset containing 3-dimensional motion and biomechanical data from 20 able-bodied adults for locomotion on solid ground and sand is collected. We present the data collection methods and report the sensor data along with the kinematic and kinetic profiles of joint biomechanics. A comprehensive analysis of human gait and joint stiffness profiles is presented. The kinematic and kinetic analysis reveals that human walking locomotion on sand shows different ground reaction forces and joint torque profiles, compared with those patterns from walking on solid ground. These gait differences reflect that humans adopt motion control strategies for yielding terrain conditions such as sand. The dataset also provides a source of locomotion data for researchers to study human activity recognition and assistive devices for walking on different terrains.

Computing the trajectories of mandibular condyles directly from MRI could provide a comprehensive examination, allowing for the extraction of both anatomical and kinematic details. This study aimed to investigate the feasibility of extracting 3D condylar trajectories from 2D real-time MRI and to assess their precision.Twenty healthy subjects underwent real-time MRI while opening and closing their jaws. One axial and two sagittal slices were segmented using a U-Net-based algorithm. The centers of mass of the resulting masks were projected onto the coordinate system based on anatomical markers and temporally adjusted using a common projection. The quality of the computed trajectories was evaluated using metrics designed to estimate movement reproducibility, head motion, and slice placement symmetry.The segmentation of the axial slices demonstrated good-to-excellent quality; however, the segmentation of the sagittal slices required some fine-tuning. The movement reproducibility was acceptable for most cases; nevertheless, head motion displaced the trajectories by 1 mm on average. The difference in the superior-inferior coordinate of the condyles in the closed jaw position was 1.7 mm on average.Despite limitations in precision, real-time MRI enables the extraction of condylar trajectories with sufficient accuracy for evaluating clinically relevant parameters such as condyle displacement, trajectories aspect, and symmetry.

Conventional industrial robots often use two-fingered grippers or suction cups to manipulate objects or interact with the world. Because of their simplified design, they are unable to reproduce the dexterity of human hands when manipulating a wide range of objects. While the control of humanoid hands evolved greatly, hardware platforms still lack capabilities, particularly in tactile sensing and providing soft contact surfaces. In this work, we present a method that equips the skeleton of a tendon-driven humanoid hand with a soft and sensorized tactile skin. Multi-material 3D printing allows us to iteratively approach a cast skin design which preserves the robot's dexterity in terms of range of motion and speed. We demonstrate that a soft skin enables firmer grasps and piezoresistive sensor integration enhances the hand's tactile sensing capabilities.

Environment awareness is crucial for enhancing walking safety and stability of amputee wearing powered prosthesis when crossing uneven terrains such as stairs and obstacles. However, existing environmental perception systems for prosthesis only provide terrain types and corresponding parameters, which fails to prevent potential collisions when crossing uneven terrains and may lead to falls and other severe consequences. In this paper, a visual-inertial motion estimation approach is proposed for prosthesis to perceive its movement and the changes of spatial relationship between the prosthesis and uneven terrain when traversing them. To achieve this, we estimate the knee motion by utilizing a depth camera to perceive the environment and align feature points extracted from stairs and obstacles. Subsequently, an error-state Kalman filter is incorporated to fuse the inertial data into visual estimations to reduce the feature extraction error and obtain a more robust estimation. The motion of prosthetic joint and toe are derived using the prosthesis model parameters. Experiment conducted on our collected dataset and stair walking trials with a powered prosthesis shows that the proposed method can accurately tracking the motion of the human leg and prosthesis with an average root-mean-square error of toe trajectory less than 5 cm. The proposed method is expected to enable the environmental adaptive control for prosthesis, thereby enhancing amputee's safety and mobility in uneven terrains.

Objective: This study aims to use artificial intelligence to realize the automatic planning of laminectomy, and verify the method. Methods: We propose a two-stage approach for automatic laminectomy cutting plane planning. The first stage was the identification of key points. 7 key points were manually marked on each CT image. The Spatial Pyramid Upsampling Network (SPU-Net) algorithm developed by us was used to accurately locate the 7 key points. In the second stage, based on the identification of key points, a personalized coordinate system was generated for each vertebra. Finally, the transverse and longitudinal cutting planes of laminectomy were generated under the coordinate system. The overall effect of planning was evaluated. Results: In the first stage, the average localization error of the SPU-Net algorithm for the seven key points was 0.65mm. In the second stage, a total of 320 transverse cutting planes and 640 longitudinal cutting planes were planned by the algorithm. Among them, the number of horizontal plane planning effects of grade A, B, and C were 318(99.38%), 1(0.31%), and 1(0.31%), respectively. The longitudinal planning effects of grade A, B, and C were 622(97.18%), 1(0.16%), and 17(2.66%), respectively. Conclusions: In this study, we propose a method for automatic surgical path planning of laminectomy based on the localization of key points in CT images. The results showed that the method achieved satisfactory results. More studies are needed to confirm the reliability of this approach in the future.

Sit-to-Stand (StS) is a fundamental daily activity that can be challenging for stroke survivors due to strength, motor control, and proprioception deficits in their lower limbs. Existing therapies involve repetitive StS exercises, but these can be physically demanding for therapists while assistive devices may limit patient participation and hinder motor learning. To address these challenges, this work proposes the use of two lower-limb exoskeletons to mediate physical interaction between therapists and patients during a StS rehabilitative task. This approach offers several advantages, including improved therapist-patient interaction, safety enforcement, and performance quantification. The whole body control of the two exoskeletons transmits online feedback between the two users, but at the same time assists in movement and ensures balance, and thus helping subjects with greater difficulty. In this study we present the architecture of the framework, presenting and discussing some technical choices made in the design.

Abstract--The placement of grab bars for elderly users is based largely on ADA building codes and does not reflect the large differences in height, mobility, and muscle power between individual persons. The goal of this study is to see if there are any correlations between an elderly user's preferred handlebar pose and various demographic indicators, self-rated mobility for tasks requiring postural change, and biomechanical markers. For simplicity, we consider only the case where the handlebar is positioned directly in front of the user, as this confines the relevant body kinematics to a 2D sagittal plane. Previous eldercare devices have been constructed to position a handlebar in various poses in space. Our work augments these devices and adds to the body of knowledge by assessing how the handlebar should be positioned based on data on actual elderly people instead of simulations.

MRI and PET are crucial diagnostic tools for brain diseases, as they provide complementary information on brain structure and function. However, PET scanning is costly and involves radioactive exposure, resulting in a lack of PET. Moreover, simultaneous PET and MRI at ultra-high-field are currently hardly infeasible. Ultra-high-field imaging has unquestionably proven valuable in both clinical and academic settings, especially in the field of cognitive neuroimaging. These motivate us to propose a method for synthetic PET from high-filed MRI and ultra-high-field MRI. From a statistical perspective, the joint probability distribution (JPD) is the most direct and fundamental means of portraying the correlation between PET and MRI. This paper proposes a novel joint diffusion attention model which has the joint probability distribution and attention strategy, named JDAM. JDAM has a diffusion process and a sampling process. The diffusion process involves the gradual diffusion of PET to Gaussian noise by adding Gaussian noise, while MRI remains fixed. JPD of MRI and noise-added PET was learned in the diffusion process. The sampling process is a predictor-corrector. PET images were generated from MRI by JPD of MRI and noise-added PET. The predictor is a reverse diffusion process and the corrector is Langevin dynamics. Experimental results on the public Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset demonstrate that the proposed method outperforms state-of-the-art CycleGAN for high-field MRI (3T MRI). Finally, synthetic PET images from the ultra-high-field (5T MRI and 7T MRI) be attempted, providing a possibility for ultra-high-field PET-MRI imaging.