However, a theoretical understanding of their success in practice is still a mystery. Moreover, recent advances [34] on fast convergence in games are limited to no-regret algorithms such as online mirror descent, which satisfy stability.

However, a theoretical understanding of their success in practice is still a mystery. Moreover, recent advances [34] on fast convergence in games are limited to no-regret algorithms such as online mirror descent, which satisfy stability.

In this paper, we study a sequential decision-making problem, called Adaptive Sampling for Discovery (ASD). Starting with a large unlabeled dataset, algorithms for ASD adaptively label the points with the goal to maximize the sum of responses. This problem has wide applications to real-world discovery problems, for example drug discovery with the help of machine learning models. ASD algorithms face the well-known exploration-exploitation dilemma. The algorithm needs to choose points that yield information to improve model estimates but it also needs to exploit the model. We rigorously formulate the problem and propose a general information-directed sampling (IDS) algorithm. We provide theoretical guarantees for the performance of IDS in linear, graph and low-rank models. The benefits of IDS are shown in both simulation experiments and real-data experiments for discovering chemical reaction conditions.

We consider online learning problems where the aim is to achieve regret which is efficient in the sense that it is the same order as the lowest regret amongst K experts. This is a substantially stronger requirement that achieving $O(\sqrt{n})$ or $O(\log n)$ regret with respect to the best expert and standard algorithms are insufficient, even in easy cases where the regrets of the available actions are very different from one another. We show that a particular lazy form of the online subgradient algorithm can be used to achieve minimal regret in a number of "easy" regimes while retaining an $O(\sqrt{n})$ worst-case regret guarantee. We also show that for certain classes of problem minimal regret strategies exist for some of the remaining "hard" regimes.