The growing importance of real-time simulation in the medical field has exposed the limitations and bottlenecks inherent in the digital representation of complex biological systems. This paper presents a novel methodology aimed at advancing current lines of research in soft tissue simulation. The proposed approach introduces a hybrid model that integrates the geometric bias of graph neural networks with the physical bias derived from the imposition of a metriplectic structure as soft and hard constrains in the architecture, being able to simulate hepatic tissue with dissipative properties. This approach provides an efficient solution capable of generating predictions at high feedback rate while maintaining a remarkable generalization ability for previously unseen anatomies. This makes these features particularly relevant in the context of precision medicine and haptic rendering. Based on the adopted methodologies, we propose a model that predicts human liver responses to traction and compression loads in as little as 7.3 milliseconds for optimized configurations and as fast as 1.65 milliseconds in the most efficient cases, all in the forward pass. The model achieves relative position errors below 0.15\%, with stress tensor and velocity estimations maintaining relative errors under 7\%. This demonstrates the robustness of the approach developed, which is capable of handling diverse load states and anatomies effectively. This work highlights the feasibility of integrating real-time simulation with patient-specific geometries through deep learning, paving the way for more robust digital human twins in medical applications.

Analog front-end design heavily relies on specialized human expertise and costly trial-and-error simulations, which motivated many prior works on analog design automation. However, efficient and effective exploration of the vast and complex design space remains constrained by the time-consuming nature of SPICE simulations, making effective design automation a challenging endeavor. In this paper, we introduce INSIGHT, a GPU-powered, technology-agnostic, effective universal neural simulator in the analog front-end design automation loop. INSIGHT accurately predicts the performance metrics of analog circuits across various technologies with just a few microseconds of inference time. Notably, its autoregressive capabilities enable INSIGHT to accurately predict simulation-costly critical transient specifications leveraging less expensive performance metric information. The low cost and high fidelity feature make INSIGHT a good substitute for standard simulators in analog front-end optimization frameworks. INSIGHT is compatible with any optimization framework, facilitating enhanced design space exploration for sample efficiency through sophisticated offline learning and adaptation techniques. Our experiments demonstrate that INSIGHT-M, a model-based batch reinforcement learning sizing framework with INSIGHT as the accurate surrogate, only requires < 20 real-time simulations with 100-1000x lower simulation costs and significant speedup over existing sizing methods.

We present a simulation strategy for the real-time dynamics of quantum fields, inspired by reinforcement learning. It builds on the complex Langevin approach, which it amends with system specific prior information, a necessary prerequisite to overcome this exceptionally severe sign problem. The optimization process underlying our machine learning approach is made possible by deploying inherently stable solvers of the complex Langevin stochastic process and a novel optimality criterion derived from insight into so-called boundary terms. This conceptual and technical progress allows us to both significantly extend the range of real-time simulations in 1+1d scalar field theory beyond the state-of-the-art and to avoid discretization artifacts that plagued previous real-time field theory simulations. Limitations of and promising future directions are discussed.

RadaRays allows for the accurate modeling and simulation of rotating FMCW radar sensors in complex environments, including the simulation of reflection, refraction, and scattering of radar waves. Our software is able to handle large numbers of objects and materials, making it suitable for use in a variety of mobile robotics applications. We demonstrate the effectiveness of RadaRays through a series of experiments and show that it can more accurately reproduce the behavior of FMCW radar sensors in a variety of environments, compared to the ray casting-based lidar-like simulations that are commonly used in simulators for autonomous driving such as CARLA. Our experiments additionally serve as valuable reference point for researchers to evaluate their own radar simulations. By using RadaRays, developers can significantly reduce the time and cost associated with prototyping and testing FMCW radar-based algorithms. We also provide a Gazebo plugin that makes our work accessible to the mobile robotics community.

Simulation is essential to reinforcement learning (RL) before implementation in the real world, especially for safety-critical applications like robot manipulation. Conventionally, RL agents are sensitive to the discrepancies between the simulation and the real world, known as the sim-to-real gap. The application of domain randomization, a technique used to fill this gap, is limited to the imposition of heuristic-randomized models. {We investigate the properties of intrinsic stochasticity of real-time simulation (RT-IS) of off-the-shelf simulation software and its potential to improve RL performance. This improvement includes a higher tolerance to noise and model imprecision and superiority to conventional domain randomization in terms of ease of use and automation. Firstly, we conduct analytical studies to measure the correlation of RT-IS with the utilization of computer hardware and validate its comparability with the natural stochasticity of a physical robot. Then, we exploit the RT-IS feature in the training of an RL agent. The simulation and physical experiment results verify the feasibility and applicability of RT-IS to robust agent training for robot manipulation tasks. The RT-IS-powered RL agent outperforms conventional agents on robots with modeling uncertainties. RT-IS requires less heuristic randomization, is not task-dependent, and achieves better generalizability than the conventional domain-randomization-powered agents. Our findings provide a new perspective on the sim-to-real problem in practical applications like robot manipulation tasks.

Although color TV is an established technology, there are a number of longstanding problems for which neural networks may be suited. Impulse noise is such a problem, and a modular neural network approach is presented in this paper. The training and analysis was done on conventional computers, while real-time simulations were performed on a massively parallel computer called the Princeton Engine. The network approach was compared to a conventional alternative, a median filter. Real-time simulations and quantitative analysis demonstrated the technical superiority of the neural system. Ongoing work is investigating the complexity and cost of implementing this system in hardware.

Although color TV is an established technology, there are a number of longstanding problems for which neural networks may be suited. Impulse noise is such a problem, and a modular neural network approach is presented in this paper. The training and analysis was done on conventional computers, while real-time simulations were performed on a massively parallel computer called the Princeton Engine. The network approach was compared to a conventional alternative, a median filter. Real-time simulations and quantitative analysis demonstrated the technical superiority of the neural system. Ongoing work is investigating the complexity and cost of implementing this system in hardware.

Although color TV is an established technology, there are a number of longstanding problems for which neural networks may be suited. Impulse noise is such a problem, and a modular neural network approach is presented inthis paper. The training and analysis was done on conventional computers, while real-time simulations were performed on a massively parallel computercalled the Princeton Engine. The network approach was compared to a conventional alternative, a median filter. Real-time simulations andquantitative analysis demonstrated the technical superiority of the neural system. Ongoing work is investigating the complexity and cost of implementing this system in hardware.