Despite the success of advanced segmentation frameworks such as TotalSegmentator (TS), accurate segmentations of the left atrial appendage (LAA), coronary arteries (CAs), and pulmonary veins (PVs) remains a significant challenge in medical imaging. In this work, we present the first open-source, anatomically coherent dataset of curated, high-resolution segmentations for these structures, supplemented with whole-heart labels produced by TS on the publicly available ImageCAS dataset consisting of 1000 cardiac computed tomography angiography (CCTA) scans. One purpose of the data set is to foster novel approaches to the analysis of LAA morphology. LAA segmentations on ImageCAS were generated using a state-of-the-art segmentation framework developed specifically for high resolution LAA segmentation. We trained the network on a large private dataset with manual annotations provided by medical readers guided by a trained cardiologist and transferred the model to ImageCAS data. CA labels were improved from the original ImageCAS annotations, while PV segmentations were refined from TS outputs. In addition, we provide a list of scans from ImageCAS that contains common data flaws such as step artefacts, LAAs extending beyond the scanner's field of view, and other types of data defects

Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with heart failure and stroke. Accurate segmentation of the left atrium (LA) in 3D late gadolinium-enhanced (LGE) MRI is helpful for evaluating AF, as fibrotic remodeling in the LA myocardium contributes to arrhythmia and serves as a key determinant of therapeutic strategies. However, manual LA segmentation is labor-intensive and challenging. Recent foundational deep learning models, such as the Segment Anything Model (SAM), pre-trained on diverse datasets, have demonstrated promise in generic segmentation tasks. MedSAM, a fine-tuned version of SAM for medical applications, enables efficient, zero-shot segmentation without domainspecific training. Despite the potential of MedSAM model, it has not yet been evaluated for the complex task of LA segmentation in 3D LGE-MRI. This study aims to (1) evaluate the performance of MedSAM in automating LA segmentation, (2) compare the performance of the MedSAM2 model, which uses a single prompt with automated tracking, with the MedSAM1 model, which requires separate prompt for each slice, and (3) analyze the performance of MedSAM1 in terms of Dice score(i.e., segmentation accuracy) by varying the size and location of the box prompt. Keywords: Foundational model, left atrial segmentation, Atrial fibrillation, Cardiac MRI (CMR), MedSAM, SAM, 3D LGE-MRI.

This paper introduces a novel magnetic navigation system for cardiac ablation. The system is formed from two key elements: a magnetic ablation catheter consisting of a chain of spherical permanent magnets; and an actuation system comprised of two cart-mounted permanent magnets undergoing pure rotation. The catheter design enables a large magnetic content with the goal of minimizing the footprint of the actuation system for easier integration with the clinical workflow. We present a quasi-static model of the catheter, the design of the actuation units, and their control modalities. Experimental validation shows that we can use small rotating magnets (119mm diameter) to reach cardiac ablation targets while generating clinically-relevant forces. Catheter control using a joystick is compared with manual catheter control. blue While total task completion time is similar, smoother navigation is observed using the proposed robotic system. We also demonstrate that the ball chain can ablate heart tissue and generate lesions comparable to the current clinical ablation catheters.

The increasing demand for the deployment of LLMs in information-seeking scenarios has spurred efforts in creating verifiable systems, which generate responses to queries along with supporting evidence. In this paper, we explore the attribution capabilities of plan-based models which have been recently shown to improve the faithfulness, grounding, and controllability of generated text. We conceptualize plans as a sequence of questions which serve as blueprints of the generated content and its organization. We propose two attribution models that utilize different variants of blueprints, an abstractive model where questions are generated from scratch, and an extractive model where questions are copied from the input. Experiments on long-form question-answering show that planning consistently improves attribution quality. Moreover, the citations generated by blueprint models are more accurate compared to those obtained from LLM-based pipelines lacking a planning component.

Atrial Fibrillation (AF) is a common electro-physiological cardiac disorder that causes changes in the anatomy of the atria. A better characterization of these changes is desirable for the definition of clinical biomarkers, and thus there is a need of its fully automatic segmentation from clinical images. In this work we present an architecture based in 3D-convolution kernels, a Volumetric Fully Convolution Neural Network (V-FCNN), able to segment the entire volume in one-shot, and consequently integrate the implicit spatial redundancy present in high resolution images. A loss function based on the mixture of both Mean Square Error (MSE) and Dice Loss (DL) is used, in an attempt to combine the ability to capture the bulk shape and the reduction of local errors products by over segmentation. Results demonstrate a reasonable performance in the middle region of the atria, and the impact of the challenges of capturing the variability of the pulmonary veins or the identification of the valve plane that separates the atria to the ventricle.