In recent years, the use of prompts to guide the output of Large Language Models have increased dramatically. However, even the best of experts struggle to choose the correct words to stitch up a prompt for the desired task. To solve this, LLM driven prompt optimization emerged as an important problem. Existing prompt optimization methods optimize a prompt globally, where in all the prompt tokens have to be optimized over a large vocabulary while solving a complex task. The large optimization space (tokens) leads to insufficient guidance for a better prompt. In this work, we introduce Local Prompt Optimization (LPO) that integrates with any general automatic prompt engineering method. We identify the optimization tokens in a prompt and nudge the LLM to focus only on those tokens in its optimization step. We observe remarkable performance improvements on Math Reasoning (GSM8k and MultiArith) and BIG-bench Hard benchmarks across various automatic prompt engineering methods. Further, we show that LPO converges to the optimal prompt faster than global methods.

Currently, the vast majority of locally deployed open-source large language models (LLMs) and some commercial model interfaces do not support stable tool calling functionality. The existing solution involves fine-tuning LLMs, which results in significant time and computational resource consumption. This paper proposes a method that enables LLMs to achieve stable tool calling capabilities using only prompt engineering and some ingenious code design. We conducted experiments on multiple LLMs that lack tool calling capabilities across various tool calling tasks, achieving a success rate of 100%.

Access to large amounts of diverse design solutions can support designers during the early stage of the design process. In this paper, we explore the efficacy of large language models (LLM) in producing diverse design solutions, investigating the level of impact that parameter tuning and various prompt engineering techniques can have on the diversity of LLM-generated design solutions. Specifically, LLMs are used to generate a total of 4,000 design solutions across five distinct design topics, eight combinations of parameters, and eight different types of prompt engineering techniques, comparing each combination of parameter and prompt engineering method across four different diversity metrics. LLM-generated solutions are compared against 100 human-crowdsourced solutions in each design topic using the same set of diversity metrics. Results indicate that human-generated solutions consistently have greater diversity scores across all design topics. Using a post hoc logistic regression analysis we investigate whether these differences primarily exist at the semantic level. Results show that there is a divide in some design topics between humans and LLM-generated solutions, while others have no clear divide. Taken together, these results contribute to the understanding of LLMs' capabilities in generating a large volume of diverse design solutions and offer insights for future research that leverages LLMs to generate diverse design solutions for a broad range of design tasks (e.g., inspirational stimuli).

This paper presents a study on the integration of domain-specific knowledge in prompt engineering to enhance the performance of large language models (LLMs) in scientific domains. A benchmark dataset is curated to encapsulate the intricate physical-chemical properties of small molecules, their drugability for pharmacology, alongside the functional attributes of enzymes and crystal materials, underscoring the relevance and applicability across biological and chemical domains.The proposed domain-knowledge embedded prompt engineering method outperforms traditional prompt engineering strategies on various metrics, including capability, accuracy, F1 score, and hallucination drop. The effectiveness of the method is demonstrated through case studies on complex materials including the MacMillan catalyst, paclitaxel, and lithium cobalt oxide. The results suggest that domain-knowledge prompts can guide LLMs to generate more accurate and relevant responses, highlighting the potential of LLMs as powerful tools for scientific discovery and innovation when equipped with domain-specific prompts. The study also discusses limitations and future directions for domain-specific prompt engineering development.

Large Language Models (LLMs) frequently suffer from knowledge-intensive questions, often being inconsistent by providing different outputs despite given the same input. The response quality worsens when the user expresses a firm opposing stance which causes the LLMs to adjust its response despite the correct initial one. These behaviors decrease the reliability and validity of the responses provided by these models. In this paper, we attempt to 1) raise awareness of the inherent risks that follow from overly relying on AI agents like ChatGPT by showing how Chain-of-Feedback (CoF) triggers LLMs to deviate more from the actual answer and 2) suggest a novel prompting method, Recursive Chain of Feedback (R-CoF), that we are conducting further study. The CoF system takes in an open-ended multi-step question. Then, we repetitively provide meaningless feedback requesting another attempt. Our preliminary experiments show that such feedback only decreases the quality of the response. On the other hand, to mitigate the effects of the aforementioned inconsistencies, we present a novel method of recursively revising the initial incorrect reasoning provided by the LLM by repetitively breaking down each incorrect step into smaller individual problems.

This study harnesses state-of-the-art AI technology for chronic disease management, specifically in detecting various mental disorders through user-generated textual content. Existing studies typically rely on fully supervised machine learning, which presents challenges such as the labor-intensive manual process of annotating extensive training data for each disease and the need to design specialized deep learning architectures for each problem. To address such challenges, we propose a novel framework that leverages advanced AI techniques, including large language models and multi-prompt engineering. Specifically, we address two key technical challenges in data-driven chronic disease management: (1) developing personalized prompts to represent each user's uniqueness and (2) incorporating medical knowledge into prompts to provide context for chronic disease detection, instruct learning objectives, and operationalize prediction goals. We evaluate our method using four mental disorders, which are prevalent chronic diseases worldwide, as research cases. On the depression detection task, our method (F1 = 0.975~0.978) significantly outperforms traditional supervised learning paradigms, including feature engineering (F1 = 0.760) and architecture engineering (F1 = 0.756). Meanwhile, our approach demonstrates success in few-shot learning, i.e., requiring only a minimal number of training examples to detect chronic diseases based on user-generated textual content (i.e., only 2, 10, or 100 subjects). Moreover, our method can be generalized to other mental disorder detection tasks, including anorexia, pathological gambling, and self-harm (F1 = 0.919~0.978).