Alzheimer's disease (AD) leads to progressive cognitive decline, making early detection crucial for effective intervention. While deep learning models have shown high accuracy in AD diagnosis, their lack of interpretability limits clinical trust and adoption. This paper introduces a novel pre-model approach leveraging Jacobian Maps (JMs) within a multi-modal framework to enhance explainability and trustworthiness in AD detection. By capturing localized brain volume changes, JMs establish meaningful correlations between model predictions and well-known neuroanatomical biomarkers of AD. We validate JMs through experiments comparing a 3D CNN trained on JMs versus on traditional preprocessed data, which demonstrates superior accuracy. We also employ 3D Grad-CAM analysis to provide both visual and quantitative insights, further showcasing improved interpretability and diagnostic reliability.

April is the beginning of the academic year in Japan and that means many children across the country are enrolling in new after-school activities. Many parents have high hopes for their child's potential when they enlist them in English and music classes, among other pursuits. But at the same time, they are worried about whether their children will be motivated enough to continue with those activities and whether their efforts will bear fruit. When it comes to keeping children motivated, however, an expert in brain science says the science is clear: It's better to praise a child's progress rather than offer materialistic rewards. According to Chihiro Hosoda, an associate professor of neuroscience at Tohoku University, the occipital lobe, which is responsible for processing and interpreting vision and color at the back of the brain, is the first to develop in children.

The outer layer of the cerebral hemisphere is termed the cerebral cortex. This is inter-connected via pathways that run sub-cortically. It is these connections as well as the connections from the cerebral cortex to the brainstem, spinal cord and nuclei deep within the cerebral hemisphere that form the white matter of the cerebral hemisphere. The deep nuclei include structures such as the basal ganglia and the thalamus. The main difference between cerebrum and cerebral cortex is that cerebrum is the largest part of the brain whereas cerebral cortex is the outer layer of the cerebrum.

Whether you read past the first line in this article or not is your choice, but inside your skull this decision will be accompanied by a buzz of activity in your neurons. But trying to pin down something as intangible as free will to a region of the brain is tricky, with most studies showing response to commands, rather than a choice made by someone's own volition. Now a team of neuroscientists in the US claim to have caught the brain in the act, capturing the activity right at the point it makes a decision – effectively pinpointing free will in the brain. Using functional MRI scans, researchers were able to show which regions showed a surge in activity which caused a boost of oxygen rich blood to the regions. Using functional MRI scans, scientists showed which brain regions had a surge in activity before a free decision is made.