Mathematical Optimization is getting more and more popular in most quantitative disciplines, such as engineering, management, economics, and operations research. Furthermore, Python is one of the most famous programming languages that is getting more attention nowadays. Therefore, we decided to create a course for mastering the development of optimization problems in the Python environment. Since this course is designed for all levels (from beginner to advanced), we start from the beginning that you need to formulate a problem. Therefore, after finishing this course, you will be able to find and formulate decision variables, objective function, constraints and define your parameters.