Interesting real-world datasets often exhibit nonlinear, noisy, continuous-valued states that are unexplorable, are poorly described by first principles, and are only partially observable. If partial observability can be overcome, these constraints suggest the use of model-based reinforcement learning. We experiment with manifold embeddings as the reconstructed observable state-space of an off-line, model-based reinforcement learning approach to control. We demonstrate the embedding of a system changes as a result of learning and that the best performing embeddings well-represent the dynamics of both the uncontrolled and adaptively controlled system. We apply this approach in simulation to learn a neurostimulation policy that is more efficient in treating epilepsy than conventional policies.

We propose a new embedding method, named Quantile-Quantile Embedding (QQE), for distribution transformation, manifold embedding, and image embedding with the ability to choose the embedding distribution. QQE, which uses the concept of quantile-quantile plot from visual statistical tests, can transform the distribution of data to any theoretical desired distribution or empirical reference sample. Moreover, QQE gives the user a choice of embedding distribution in embedding manifold of data into the low dimensional embedding space. It can also be used for modifying the embedding distribution of different dimensionality reduction methods, either basic or deep ones, for better representation or visualization of data. We propose QQE in both unsupervised and supervised manners. QQE can also transform the distribution to either the exact reference distribution or shape of the reference distribution; and one of its many applications is better discrimination of classes. Our experiments on different synthetic and image datasets show the effectiveness of the proposed embedding method.

Interesting real-world datasets often exhibit nonlinear, noisy, continuous-valued states that are unexplorable, are poorly described by first principles, and are only partially observable. If partial observability can be overcome, these constraints suggest the use of model-based reinforcement learning. We experiment with manifold embeddings as the reconstructed observable state-space of an off-line, model-based reinforcement learning approach to control. We demonstrate the embedding of a system changes as a result of learning and that the best performing embeddings well-represent the dynamics of both the uncontrolled and adaptively controlled system. We apply this approach in simulation to learn a neurostimulation policy that is more efficient in treating epilepsy than conventional policies.

Interesting real-world datasets often exhibit nonlinear, noisy, continuous-valued states that are unexplorable, are poorly described by first principles, and are only partially observable. If partial observability can be overcome, these constraints suggest the use of model-based reinforcement learning. We experiment with manifold embeddings as the reconstructed observable state-space of an off-line, model-based reinforcement learning approach to control. We demonstrate the embedding of a system changes as a result of learning and that the best performing embeddings well-represent the dynamics of both the uncontrolled and adaptively controlled system. We apply this approach in simulation to learn a neurostimulation policy that is more efficient in treating epilepsy than conventional policies. We then demonstrate the learned policy completely suppressing seizures in real-world neurostimulation experiments on actual animal brain slices.