Neural Information Processing Systems http://nips.cc/

We therefore assume that the algorithm has access to an oracle that knows intuitively what it means to be fair, but cannot explicitly enunciate the fairness metric.

Neural Information Processing Systems http://nips.cc/

Equipped with the knowledge of sample difficulty, we further propose to use it for regularizing the prediction confidence.

Section 5,Section 6andSection 8 explain more implementation details of the empirical implementation. We use "M" or "S" to distinguish contents inthemain fileorinthesupplementary file.

Quantitative imaging methods, such as magnetic resonance fingerprinting (MRF), aim to extract interpretable pathology biomarkers by estimating biophysical tissue parameters from signal evolutions. However, the pattern-matching algorithms or neural networks used in such inverse problems often lack principled uncertainty quantification, which limits the trustworthiness and transparency, required for clinical acceptance. Here, we describe a physics-structured variational autoencoder (PS-VAE) designed for rapid extraction of voxelwise multi-parameter posterior distributions. Our approach integrates a differentiable spin physics simulator with self-supervised learning, and provides a full covariance that captures the inter-parameter correlations of the latent biophysical space. The method was validated in a multi-proton pool chemical exchange saturation transfer (CEST) and semisolid magnetization transfer (MT) molecular MRF study, across in-vitro phantoms, tumor-bearing mice, healthy human volunteers, and a subject with glioblastoma. The resulting multi-parametric posteriors are in good agreement with those calculated using a brute-force Bayesian analysis, while providing an orders-of-magnitude acceleration in whole brain quantification. In addition, we demonstrate how monitoring the multi-parameter posterior dynamics across progressively acquired signals provides practical insights for protocol optimization and may facilitate real-time adaptive acquisition.

Supporting Go/No-Go decisions prior to launch requires assessing real-time telemetry data against redline limits established during the design qualification phase. Family data from ground testing or previous flights is commonly used to detect initiating failure modes and their timing; however, this approach relies heavily on engineering judgment and is more error-prone for new launch vehicles. To address these limitations, we utilize Long-Term Short-Term Memory (LSTM) networks for supervised classification of time-series anomalies. Although, initial training labels derived from simulated anomaly data may be suboptimal due to variations in anomaly strength, anomaly settling times, and other factors. In this work, we propose a novel statistical detector based on the Mahalanobis distance and forward-backward detection fractions to adjust the supervised training labels. We demonstrate our method on digital twin simulations of a ground-stage propulsion system with 20.8 minutes of operation per trial and O(10^8) training timesteps. The statistical data relabeling improved precision and recall of the LSTM classifier by 7% and 22% respectively.