learning signature
Learning signatures of decision making from many individuals playing the same game
Mendelson, Michael J, Azabou, Mehdi, Jacob, Suma, Grissom, Nicola, Darrow, David, Ebitz, Becket, Herman, Alexander, Dyer, Eva L.
Human behavior is incredibly complex and the factors that drive decision making--from instinct, to strategy, to biases between individuals--often vary over multiple timescales. In this paper, we design a predictive framework that learns representations to encode an individual's 'behavioral style', i.e. long-term behavioral trends, while simultaneously predicting future actions and choices. The model explicitly separates representations into three latent spaces: the recent past space, the short-term space, and the long-term space where we hope to capture individual differences. To simultaneously extract both global and local variables from complex human behavior, our method combines a multi-scale temporal convolutional network with latent prediction tasks, where we encourage embeddings across the entire sequence, as well as subsets of the sequence, to be mapped to similar points in the latent space. We develop and apply our method to a large-scale behavioral dataset from 1,000 humans playing a 3-armed bandit task, and analyze what our model's resulting embeddings reveal about the human decision making process. In addition to predicting future choices, we show that our model can learn rich representations of human behavior over multiple timescales and provide signatures of differences in individuals.
A nomogram based on CT deep learning signature
Xianyue Quan Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, People's Republic of China Tel/Fax 86-2061643114 Email quanxianyue2014@163.com Purpose: To develop and further validate a deep learning signature-based nomogram from computed tomography (CT) images for prediction of the overall survival (OS) in resected non-small cell lung cancer (NSCLC) patients. Patients and Methods: A total of 1792 deep learning features were extracted from non-enhanced and venous-phase CT images for each NSCLC patient in training cohort (n 231). Then, a deep learning signature was built with the least absolute shrinkage and selection operator (LASSO) Cox regression model for OS estimation. At last, a nomogram was constructed with the signature and other independent clinical risk factors. The performance of nomogram was assessed by discrimination, calibration and clinical usefulness.