In recent years, the deployment of large-scale pre-trained models in audio-visual downstream tasks has yielded remarkable outcomes. However, these models, primarily trained on single-modality unconstrained datasets, still encounter challenges in feature extraction for multi-modal tasks, leading to suboptimal performance. This limitation arises due to the introduction of irrelevant modality-specific information during encoding, which adversely affects the performance of downstream tasks. To address this challenge, this paper proposes a novel Dual-Guided Spatial-Channel-Temporal (DG-SCT) attention mechanism. This mechanism leverages audio and visual modalities as soft prompts to dynamically adjust the parameters of pre-trained models based on the current multi-modal input features. Specifically, the DG-SCT module incorporates trainable cross-modal interaction layers into pre-trained audio-visual encoders, allowing adaptive extraction of crucial information from the current modality across spatial, channel, and temporal dimensions, while preserving the frozen parameters of large-scale pre-trained models. Experimental evaluations demonstrate that our proposed model achieves state-of-the-art results across multiple downstream tasks, including AVE, AVVP, AVS, and AVQA. Furthermore, our model exhibits promising performance in challenging few-shot and zero-shot scenarios.

Noise ubiquitously exists in signals due to numerous factors including physical, electronic, and environmental effects. Traditional methods of symbolic regression, such as genetic programming or deep learning models, aim to find the most fitting expressions for these signals. However, these methods often overlook the noise present in real-world data, leading to reduced fitting accuracy. To tackle this issue, we propose \textit{\textbf{D}eep Symbolic Regression against \textbf{N}oise via \textbf{C}ontrastive \textbf{L}earning (DN-CL)}. DN-CL employs two parameter-sharing encoders to embed data points from various data transformations into feature shields against noise. This model treats noisy data and clean data as different views of the ground-truth mathematical expressions. Distances between these features are minimized, utilizing contrastive learning to distinguish between 'positive' noise-corrected pairs and 'negative' contrasting pairs. Our experiments indicate that DN-CL demonstrates superior performance in handling both noisy and clean data, presenting a promising method of symbolic regression.

News captioning task aims to generate sentences by describing named entities or concrete events for an image with its news article. Existing methods have achieved remarkable results by relying on the large-scale pre-trained models, which primarily focus on the correlations between the input news content and the output predictions. However, the news captioning requires adhering to some fundamental rules of news reporting, such as accurately describing the individuals and actions associated with the event. In this paper, we propose the rule-driven news captioning method, which can generate image descriptions following designated rule signal. Specifically, we first design the news-aware semantic rule for the descriptions. This rule incorporates the primary action depicted in the image (e.g., "performing") and the roles played by named entities involved in the action (e.g., "Agent" and "Place"). Second, we inject this semantic rule into the large-scale pre-trained model, BART, with the prefix-tuning strategy, where multiple encoder layers are embedded with news-aware semantic rule. Finally, we can effectively guide BART to generate news sentences that comply with the designated rule. Extensive experiments on two widely used datasets (i.e., GoodNews and NYTimes800k) demonstrate the effectiveness of our method.

Transformer-based deep neural networks have revolutionized the field of molecular-related prediction tasks by treating molecules as symbolic sequences. These models have been successfully applied in various organic chemical applications by pretraining them with extensive compound libraries and subsequently fine-tuning them with smaller in-house datasets for specific tasks. However, many conventional methods primarily focus on single molecules, with limited exploration of pretraining for reactions involving multiple molecules. In this paper, we propose ReactionT5, a novel model that leverages pretraining on the Open Reaction Database (ORD), a publicly available large-scale resource. We further fine-tune this model for yield prediction and product prediction tasks, demonstrating its impressive performance even with limited fine-tuning data compared to traditional models. The pre-trained ReactionT5 model is publicly accessible on the Hugging Face platform.

Domain generalization aims to build generalized models that perform well on unseen domains when only source domains are available for model optimization. Recent studies have shown that large-scale pre-trained models can enhance domain generalization by leveraging their generalization power. However, these pre-trained models lack target task-specific knowledge yet due to discrepancies between the pre-training objectives and the target task. Although the task-specific knowledge could be learned from source domains by fine-tuning, this hurts the generalization power of pre-trained models due to gradient bias toward the source domains. To alleviate this problem, we propose a new domain generalization method that estimates unobservable gradients that reduce potential risks in unseen domains using a large-scale pre-trained model. These estimated unobservable gradients allow the pre-trained model to learn task-specific knowledge further while preserving its generalization ability by relieving the gradient bias. Our experimental results show that our method outperforms baseline methods on DomainBed, a standard benchmark in domain generalization. We also provide extensive analyses to demonstrate that the pre-trained model can learn task-specific knowledge without sacrificing its generalization power.

With the success of large-scale pre-trained models (PTMs), how efficiently adapting PTMs to downstream tasks has attracted tremendous attention, especially for PTMs with billions of parameters. Although some parameter-efficient tuning paradigms have been proposed to address this problem, they still require large resources to compute the gradients in the training phase. In this paper, we propose $\mathcal{Y}$-Tuning, an efficient yet effective paradigm to adapt frozen large-scale PTMs to specific downstream tasks. $\mathcal{Y}$-tuning learns dense representations for labels $\mathcal{Y}$ defined in a given task and aligns them to fixed feature representation. Without tuning the features of input text and model parameters, $\mathcal{Y}$-tuning is both parameter-efficient and training-efficient. For $\text{DeBERTa}_\text{XXL}$ with 1.6 billion parameters, $\mathcal{Y}$-tuning achieves performance more than $96\%$ of full fine-tuning on GLUE Benchmark with only $2\%$ tunable parameters and much fewer training costs.