Epilepsy is a chronic neurological disorder with a significant prevalence. However, there is still no adequate technological support to enable epilepsy detection and continuous outpatient monitoring in everyday life. Hyperdimensional (HD) computing is an interesting alternative for wearable devices, characterized by a much simpler learning process and also lower memory requirements. In this work, we demonstrate a few additional aspects in which HD computing, and the way its models are built and stored, can be used for further understanding, comparing, and creating more advanced machine learning models for epilepsy detection. These possibilities are not feasible with other state-of-the-art models, such as random forests or neural networks. We compare inter-subject similarity of models per different classes (seizure and non-seizure), then study the process of creation of generalized models from personalized ones, and in the end, how to combine personalized and generalized models to create hybrid models. This results in improved epilepsy detection performance. We also tested knowledge transfer between models created on two different datasets. Finally, all those examples could be highly interesting not only from an engineering perspective to create better models for wearables, but also from a neurological perspective to better understand individual epilepsy patterns.

HyperDimensional Computing (HDC) as a machine learning paradigm is highly interesting for applications involving continuous, semi-supervised learning for long-term monitoring. However, its accuracy is not yet on par with other Machine Learning (ML) approaches. Frameworks enabling fast design space exploration to find practical algorithms are necessary to make HD computing competitive with other ML techniques. To this end, we introduce HDTorch, an open-source, PyTorch-based HDC library with CUDA extensions for hypervector operations. We demonstrate HDTorch's utility by analyzing four HDC benchmark datasets in terms of accuracy, runtime, and memory consumption, utilizing both classical and online HD training methodologies. We demonstrate average (training)/inference speedups of (111x/68x)/87x for classical/online HD, respectively. Moreover, we analyze the effects of varying hyperparameters on runtime and accuracy. Finally, we demonstrate how HDTorch enables exploration of HDC strategies applied to large, real-world datasets. We perform the first-ever HD training and inference analysis of the entirety of the CHB-MIT EEG epilepsy database. Results show that the typical approach of training on a subset of the data does not necessarily generalize to the entire dataset, an important factor when developing future HD models for medical wearable devices.

Hyperdimensional (HD) computing is a set of neurally inspired methods for obtaining highdimensional, low-precision, distributed representations of data. These representations can be combined with simple, neurally plausible algorithms to effect a variety of information processing tasks. HD computing has recently garnered significant interest from the computer hardware community as an energy-efficient, low-latency, and noise-robust tool for solving learning problems. In this review, we present a unified treatment of the theoretical foundations of HD computing with a focus on the suitability of representations for learning.

Machine learning models differ in terms of accuracy, computational/memory complexity, training time, and adaptability among other characteristics. For example, neural networks (NNs) are well-known for their high accuracy due to the quality of their automatic feature extraction while brain-inspired hyperdimensional (HD) learning models are famous for their quick training, computational efficiency, and adaptability. This work presents a hybrid, synergic machine learning model that excels at all the said characteristics and is suitable for incremental, on-line learning on a chip. The proposed model comprises an NN and a classifier. The NN acts as a feature extractor and is specifically trained to work well with the classifier that employs the HD computing framework. This work also presents a parameterized hardware implementation of the said feature extraction and classification components while introducing a compiler that maps any arbitrary NN and/or classifier to the aforementioned hardware. The proposed hybrid machine learning model has the same level of accuracy (i.e. $\pm$1%) as NNs while achieving at least 10% improvement in accuracy compared to HD learning models. Additionally, the end-to-end hardware realization of the hybrid model improves power efficiency by 1.60x compared to state-of-the-art, high-performance HD learning implementations while improving latency by 2.13x. These results have profound implications for the application of such synergic models in challenging cognitive tasks.

Hyperdimensional (HD) computing is built upon its unique data type referred to as hypervectors. The dimension of these hypervectors is typically in the range of tens of thousands. Proposed to solve cognitive tasks, HD computing aims at calculating similarity among its data. Data transformation is realized by three operations, including addition, multiplication and permutation. Its ultra-wide data representation introduces redundancy against noise. Since information is evenly distributed over every bit of the hypervectors, HD computing is inherently robust. Additionally, due to the nature of those three operations, HD computing leads to fast learning ability, high energy efficiency and acceptable accuracy in learning and classification tasks. This paper introduces the background of HD computing, and reviews the data representation, data transformation, and similarity measurement. The orthogonality in high dimensions presents opportunities for flexible computing. To balance the tradeoff between accuracy and efficiency, strategies include but are not limited to encoding, retraining, binarization and hardware acceleration. Evaluations indicate that HD computing shows great potential in addressing problems using data in the form of letters, signals and images. HD computing especially shows significant promise to replace machine learning algorithms as a light-weight classifier in the field of internet of things (IoTs).

This paper presents an efficient binarized algorithm for both learning and classification of human epileptic seizures from intracranial electroencephalography (iEEG). The algorithm combines local binary patterns with brain-inspired hyperdimensional computing to enable end-to-end learning and inference with binary operations. The algorithm first transforms iEEG time series from each electrode into local binary pattern codes. Then atomic high-dimensional binary vectors are used to construct composite representations of seizures across all electrodes. For the majority of our patients (10 out of 16), the algorithm quickly learns from one or two seizures (i.e., one-/few-shot learning) and perfectly generalizes on 27 further seizures. For other patients, the algorithm requires three to six seizures for learning. Overall, our algorithm surpasses the state-of-the-art methods for detecting 65 novel seizures with higher specificity and sensitivity, and lower memory footprint.