Genomic selection (GS), as a critical crop breeding strategy, plays a key role in enhancing food production and addressing the global hunger crisis. The predominant approaches in GS currently revolve around employing statistical methods for prediction. However, statistical methods often come with two main limitations: strong statistical priors and linear assumptions. A recent trend is to capture the non-linear relationships between markers by deep learning. However, as crop datasets are commonly long sequences with limited samples, the robustness of deep learning models, especially Transformers, remains a challenge. In this work, to unleash the unexplored potential of attention mechanism for the task of interest, we propose a simple yet effective Transformer-based framework that enables end-to-end training of the whole sequence. Via experiments on rice3k and wheat3k datasets, we show that, with simple tricks such as k-mer tokenization and random masking, Transformer can achieve overall superior performance against seminal methods on GS tasks of interest.

Scientists revealed the use of artificial intelligence to predict the sugarcane industry's performance efficiently.

Genomic selection (GS) is a technique that plant breeders use to select individuals to mate and produce new generations of species. Allocation of resources is a key factor in GS. At each selection cycle, breeders are facing the choice of budget allocation to make crosses and produce the next generation of breeding parents. Inspired by recent advances in reinforcement learning for AI problems, we develop a reinforcement learning-based algorithm to automatically learn to allocate limited resources across different generations of breeding. We mathematically formulate the problem in the framework of Markov Decision Process (MDP) by defining state and action spaces. To avoid the explosion of the state space, an integer linear program is proposed that quantifies the trade-off between resources and time. Finally, we propose a value function approximation method to estimate the action-value function and then develop a greedy policy improvement technique to find the optimal resources. We demonstrate the effectiveness of the proposed method in enhancing genetic gain using a case study with realistic data.