Efficient data indexing and exact k-nearest-neighbor (kNN) retrieval are still challenging tasks in high-dimensional spaces. This work highlights the difficulties of indexing in high-dimensional and tightly-clustered dataspaces by exploring several important tunable parameters for optimizing kNN query performance using the iDistance and iDStar algorithms. We experiment on real and synthetic datasets of varying size, cluster density, and dimensionality, and compare performance primarily through filter-and-refine efficiency and execution time. Results show great variability over parameter values and provide new insights and justifications in support of prior best-use practices. Local segmentation with iDStar consistently outperforms iDistance in any clustered space below 256 dimensions, setting a new benchmark for efficient and exact kNN retrieval in high-dimensional spaces. We propose several directions of future work to further increase performance in high-dimensional real-world settings.