Scalable and generalizable analysis of brain activity is essential for advancing both clinical diagnostics and cognitive research. Electroencephalography (EEG), a non-invasive modality with high temporal resolution, has been widely used for brain states analysis. However, most existing EEG models are usually tailored for individual specific tasks, limiting their utility in realistic scenarios where EEG analysis often involves multi-task and continuous reasoning. In this work, we introduce EEGAgent, a general-purpose framework that leverages large language models (LLMs) to schedule and plan multiple tools to automatically complete EEG-related tasks. EEGAgent is capable of performing the key functions: EEG basic information perception, spatiotemporal EEG exploration, EEG event detection, interaction with users, and EEG report generation. To realize these capabilities, we design a toolbox composed of different tools for EEG prepro-cessing, feature extraction, event detection, etc. These capabilities were evaluated on public datasets, and our EEGAgent can support flexible and interpretable EEG analysis, highlighting its potential for real-world clinical applications.

This work explores the potential of foundation models, specifically a Mamba-based selective state space model, for enhancing EEG analysis in neurological disorder diagnosis. EEG, crucial for diagnosing conditions like epilepsy, presents significant challenges due to its noisy, high-dimensional, and nonlinear nature. Traditional machine learning methods have made advances in automating EEG analysis but often fail to capture its complex spatio-temporal dynamics. Recent advances in deep learning, particularly in sequence modeling, offer new avenues for creating more generalized and expressive models capable of handling such complexities. By training a Mamba-based model on a large dataset containing seizure and non-seizure EEG recordings through a self-supervised reconstruction task followed by a seizure detection task, we demonstrate the model's effectiveness, achieving an AUROC of 0.72 on a held-out test set. This approach marks a significant step toward developing large-scale, clinically applicable foundation models for EEG data analysis.

The difficulty of extracting deep features from EEG data and effectively integrating information from multiple views presents significant challenges for developing a generalizable pretraining framework for EEG representation learning. However, most existing pre-training methods rely solely on the contextual semantics of a single view, failing to capture the complex and synergistic interactions among different perspectives, limiting the expressiveness and generalization of learned representations. To address these issues, this paper proposes CRIA, an adaptive framework that utilizes variable-length and variable-channel coding to achieve a unified representation of EEG data across different datasets. In this work, we define cross-view information as the integrated representation that emerges from the interaction among temporal, spectral, and spatial views of EEG signals. The model employs a cross-attention mechanism to fuse temporal, spectral, and spatial features effectively, and combines an attention matrix masking strategy based on the information bottleneck principle with a novel viewpoint masking pre-training scheme. Experimental results on the Temple University EEG corpus and the CHB-MIT dataset show that CRIA outperforms existing methods with the same pre-training conditions, achieving a balanced accuracy of 57.02% for multi-class event classification and 80.03% for anomaly detection, highlighting its strong generalization ability.

Abstract--The growing convergence between Large Language Models (LLMs) and electroencephalography (EEG) research is enabling new directions in neural decoding, brain-computer interfaces (BCIs), and affective computing. This survey offers a systematic review and structured taxonomy of recent advancements that utilize LLMs for EEG-based analysis and applications. We organize the recent studies into four categories: (1) LLM-inspired foundation models for EEG analysis, (2) EEG-to-language decoding, (3) cross-modal generation including image and 3D object synthesis, and (4) clinical applications and dataset management tools. The survey highlights how transformer-based architectures adapted through fine-tuning, few-shot, and zero-shot learning have enabled EEG-based models to perform complex tasks such as natural language generation, semantic interpretation, and diagnostic assistance. By presenting a structured overview of the employed models and application domains, this survey establishes a comprehensive framework to advance neural signal analysis through the application of language models. The growing use of language models is shaping new developments in both neuroscience and artificial intelligence. Language models such as GPT, BERT [1], [2], [3], and their multi-modal variants have shown remarkable success across tasks involving natural language processing and understanding, generation, and even vision-language fusion. The transformer-based architecture enables these models to effectively process sequential data, contributing to their success across a range of domains beyond natural language processing.

The success of foundation models in natural language processing and computer vision has motivated similar approaches for general time series analysis. While these models are effective for a variety of tasks, their applicability in medical domains with limited data remains largely unexplored. To address this, we investigate the effectiveness of foundation models in medical time series analysis involving electroencephalography (EEG). Through extensive experiments on tasks such as age prediction, seizure detection, and the classification of clinically relevant EEG events, we compare their diagnostic accuracy with that of specialised EEG models. Our analysis shows that foundation models extract meaningful EEG features, outperform specialised models even without domain adaptation, and localise task-specific biomarkers. Moreover, we demonstrate that diagnostic accuracy is substantially influenced by architectural choices such as context length. Overall, our study reveals that foundation models with general time series understanding eliminate the dependency on large domain-specific datasets, making them valuable tools for clinical practice.

Accurate and efficient electroencephalography (EEG) analysis is essential for detecting seizures and artifacts in long-term monitoring, with applications spanning hospital diagnostics to wearable health devices. Robust EEG analytics have the potential to greatly improve patient care. However, traditional deep learning models, especially Transformer-based architectures, are hindered by their quadratic time and memory complexity, making them less suitable for resource-constrained environments. To address these challenges, we present FEMBA (Foundational EEG Mamba + Bidirectional Architecture), a novel self-supervised framework that establishes new efficiency benchmarks for EEG analysis through bidirectional state-space modeling. Unlike Transformer-based models, which incur quadratic time and memory complexity, FEMBA scales linearly with sequence length, enabling more scalable and efficient processing of extended EEG recordings. Trained on over 21,000 hours of unlabeled EEG and fine-tuned on three downstream tasks, FEMBA achieves competitive performance in comparison with transformer models, with significantly lower computational cost. Specifically, it reaches 81.82% balanced accuracy (0.8921 AUROC) on TUAB and 0.949 AUROC on TUAR, while a tiny 7.8M-parameter variant demonstrates viability for resource-constrained devices. These results pave the way for scalable, general-purpose EEG analytics in both clinical and highlight FEMBA as a promising candidate for wearable applications.

Electroencephalography (EEG) signals provide critical insights for applications in disease diagnosis and healthcare. However, the scarcity of labeled EEG data poses a significant challenge. Foundation models offer a promising solution by leveraging large-scale unlabeled data through pre-training, enabling strong performance across diverse tasks. While both temporal dynamics and inter-channel relationships are vital for understanding EEG signals, existing EEG foundation models primarily focus on the former, overlooking the latter. To address this limitation, we propose a novel foundation model for EEG that integrates both temporal and inter-channel information. Our architecture combines Graph Neural Networks (GNNs), which effectively capture relational structures, with a masked autoencoder to enable efficient pre-training. We evaluated our approach using three downstream tasks and experimented with various GNN architectures. The results demonstrate that our proposed model, particularly when employing the GCN architecture with optimized configurations, consistently outperformed baseline methods across all tasks. These findings suggest that our model serves as a robust foundation model for EEG analysis.

Independent component analysis (ICA) is a widely used method in various applications of signal processing and feature extraction. It extends principal component analysis (PCA) and can extract important and complicated components with small variances. One of the major problems of ICA is that the uniqueness of the solution is not guaranteed, unlike PCA. That is because there are many local optima in optimizing the objective function of ICA. It has been shown previously that the unique global optimum of ICA can be estimated from many random initializations by handcrafted thread computation. In this paper, the unique estimation of ICA is highly accelerated by reformulating the algorithm in matrix representation and reducing redundant calculations. Experimental results on artificial datasets and EEG data verified the efficiency of the proposed method.

Electroencephalography (EEG) analysis is an important domain in the realm of Brain-Computer Interface (BCI) research. To ensure BCI devices are capable of providing practical applications in the real world, brain signal processing techniques must be fast, accurate, and resource-conscious to deliver low-latency neural analytics. This study presents a model that leverages a pre-trained MobileViT alongside Knowledge Distillation (KD) for EEG regression tasks. Our results showcase that this model is capable of performing at a level comparable (only 3% lower) to the previous State-Of-The-Art (SOTA) on the EEGEyeNet Absolute Position Task while being 33% faster and 60% smaller. Our research presents a cost-effective model applicable to resource-constrained devices and contributes to expanding future research on lightweight, mobile-friendly models for EEG regression.

The task of Electroencephalogram (EEG) analysis is paramount to the development of Brain-Computer Interfaces (BCIs). However, to reach the goal of developing robust, useful BCIs depends heavily on the speed and the accuracy at which BCIs can understand neural dynamics. In response to that goal, this paper details the integration of pre-trained Vision Transformers (ViTs) with Temporal Convolutional Networks (TCNet) to enhance the precision of EEG regression. The core of this approach lies in harnessing the sequential data processing strengths of ViTs along with the superior feature extraction capabilities of TCNet, to significantly improve EEG analysis accuracy. In addition, we analyze the importance of how to construct optimal patches for the attention mechanism to analyze, balancing both speed and accuracy tradeoffs. Our results showcase a substantial improvement in regression accuracy, as evidenced by the reduction of Root Mean Square Error (RMSE) from 55.4 to 51.8 on EEGEyeNet's Absolute Position Task, outperforming existing state-of-the-art models. Without sacrificing performance, we increase the speed of this model by an order of magnitude (up to 4.32x faster). This breakthrough not only sets a new benchmark in EEG regression analysis but also opens new avenues for future research in the integration of transformer architectures with specialized feature extraction methods for diverse EEG datasets.