Power and accuracy of Artificial intelligence (AI) presents a unique opportunity to transform all industries. But AI true potential could be harnessed in health care by making a life-changing impact on millions of lives. Across the health care value chain from bench-side to bed-side, from drug development to insurance, from standard hospital care to clinical research, AI applications have the potential to improve patient health care outcomes, revolutionize the workflow, and reduce the cost of care. Across the Health care functions where AI could potentially create strategic infliction point are'General Wellness/Patient Monitoring with wearables & IoT', 'Early Disease Detection and Diagnostics using deep learning', and'Precision Medicine Research'. There is also an uphill task in terms of change management to include the AI into Health Care workflows as there are legal barriers, sense of skepticism on impact and fear of breach of privacy, and cloud of job insecurity.