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Combining Fully Convolutional and Recurrent Neural Networks for 3D Biomedical Image Segmentation

Neural Information Processing Systems

Segmentation of 3D images is a fundamental problem in biomedical image analysis. Deep learning (DL) approaches have achieved the state-of-the-art segmentation performance. To exploit the 3D contexts using neural networks, known DL segmentation methods, including 3D convolution, 2D convolution on the planes orthogonal to 2D slices, and LSTM in multiple directions, all suffer incompatibility with the highly anisotropic dimensions in common 3D biomedical images. In this paper, we propose a new DL framework for 3D image segmentation, based on a combination of a fully convolutional network (FCN) and a recurrent neural network (RNN), which are responsible for exploiting the intra-slice and inter-slice contexts, respectively. To our best knowledge, this is the first DL framework for 3D image segmentation that explicitly leverages 3D image anisotropism. Evaluating using a dataset from the ISBI Neuronal Structure Segmentation Challenge and in-house image stacks for 3D fungus segmentation, our approach achieves promising results, comparing to the known DL-based 3D segmentation approaches.





GPU Temperature Simulation-Based Testing for In-Vehicle Deep Learning Frameworks

Zou, Yinglong, Zhai, Juan, Fang, Chunrong, Chen, Zhenyu

arXiv.org Artificial Intelligence

Deep learning models play a vital role in autonomous driving systems, supporting critical functions such as environmental perception. To accelerate model inference, these deep learning models' deployment relies on automotive deep learning frameworks, for example, PaddleInference in Apollo and TensorRT in AutoWare. However, unlike deploying deep learning models on the cloud, vehicular environments experience extreme ambient temperatures varying from -40°C to 50°C, significantly impacting GPU temperature. Additionally, heats generated when computing further lead to the GPU temperature increase. These temperature fluctuations lead to dynamic GPU frequency adjustments through mechanisms such as DVFS. However, automotive deep learning frameworks are designed without considering the impact of temperature-induced frequency variations. When deployed on temperature-varying GPUs, these frameworks suffer critical quality issues: compute-intensive operators face delays or errors, high/mixed-precision operators suffer from precision errors, and time-series operators suffer from synchronization issues. The above quality issues cannot be detected by existing deep learning framework testing methods because they ignore temperature's effect on the deep learning framework quality. To bridge this gap, we propose ThermalGuardian, the first automotive deep learning framework testing method under temperature-varying environments. Specifically, ThermalGuardian generates test input models using model mutation rules targeting temperature-sensitive operators, simulates GPU temperature fluctuations based on Newton's law of cooling, and controls GPU frequency based on real-time GPU temperature.



The Foundation Cracks: A Comprehensive Study on Bugs and Testing Practices in LLM Libraries

Jiang, Weipeng, Zhang, Xiaoyu, Xie, Xiaofei, Yu, Jiongchi, Zhi, Yuhan, Ma, Shiqing, Shen, Chao

arXiv.org Artificial Intelligence

Large Language Model (LLM) libraries have emerged as the foundational infrastructure powering today's AI revolution, serving as the backbone for LLM deployment, inference optimization, fine-tuning, and production serving across diverse applications. Despite their critical role in the LLM ecosystem, these libraries face frequent quality issues and bugs that threaten the reliability of AI systems built upon them. To address this knowledge gap, we present the first comprehensive empirical investigation into bug characteristics and testing practices in modern LLM libraries. We examine 313 bug-fixing commits extracted across two widely-adopted LLM libraries: HuggingFace Transformers and vLLM.Through rigorous manual analysis, we establish comprehensive taxonomies categorizing bug symptoms into 5 types and root causes into 14 distinct categories.Our primary discovery shows that API misuse has emerged as the predominant root cause (32.17%-48.19%), representing a notable transition from algorithm-focused defects in conventional deep learning frameworks toward interface-oriented problems. Additionally, we examine 7,748 test functions to identify 7 distinct test oracle categories employed in current testing approaches, with predefined expected outputs (such as specific tensors and text strings) being the most common strategy. Our assessment of existing testing effectiveness demonstrates that the majority of bugs escape detection due to inadequate test cases (41.73%), lack of test drivers (32.37%), and weak test oracles (25.90%). Drawing from these findings, we offer some recommendations for enhancing LLM library quality assurance.


Introducing Interval Neural Networks for Uncertainty-Aware System Identification

Ferah, Mehmet Ali, Kumbasar, Tufan

arXiv.org Artificial Intelligence

System Identification (SysID) is crucial for modeling and understanding dynamical systems using experimental data. While traditional SysID methods emphasize linear models, their inability to fully capture nonlinear dynamics has driven the adoption of Deep Learning (DL) as a more powerful alternative. However, the lack of uncertainty quantification (UQ) in DL-based models poses challenges for reliability and safety, highlighting the necessity of incorporating UQ. This paper introduces a systematic framework for constructing and learning Interval Neural Networks (INNs) to perform UQ in SysID tasks. INNs are derived by transforming the learnable parameters (LPs) of pre-trained neural networks into interval-valued LPs without relying on probabilistic assumptions. By employing interval arithmetic throughout the network, INNs can generate Prediction Intervals (PIs) that capture target coverage effectively. We extend Long Short-Term Memory (LSTM) and Neural Ordinary Differential Equations (Neural ODEs) into Interval LSTM (ILSTM) and Interval NODE (INODE) architectures, providing the mathematical foundations for their application in SysID. To train INNs, we propose a DL framework that integrates a UQ loss function and parameterization tricks to handle constraints arising from interval LPs. We introduce novel concept "elasticity" for underlying uncertainty causes and validate ILSTM and INODE in SysID experiments, demonstrating their effectiveness.


Combining Fully Convolutional and Recurrent Neural Networks for 3D Biomedical Image Segmentation

Neural Information Processing Systems

Segmentation of 3D images is a fundamental problem in biomedical image analysis. Deep learning (DL) approaches have achieved the state-of-the-art segmentation performance. To exploit the 3D contexts using neural networks, known DL segmentation methods, including 3D convolution, 2D convolution on the planes orthogonal to 2D slices, and LSTM in multiple directions, all suffer incompatibility with the highly anisotropic dimensions in common 3D biomedical images. In this paper, we propose a new DL framework for 3D image segmentation, based on a combination of a fully convolutional network (FCN) and a recurrent neural network (RNN), which are responsible for exploiting the intra-slice and inter-slice contexts, respectively. To our best knowledge, this is the first DL framework for 3D image segmentation that explicitly leverages 3D image anisotropism.


Impact of Recurrent Neural Networks and Deep Learning Frameworks on Real-time Lightweight Time Series Anomaly Detection

Lee, Ming-Chang, Lin, Jia-Chun, Katsikas, Sokratis

arXiv.org Artificial Intelligence

Real-time lightweight time series anomaly detection has become increasingly crucial in cybersecurity and many other domains. Its ability to adapt to unforeseen pattern changes and swiftly identify anomalies enables prompt responses and critical decision-making. While several such anomaly detection approaches have been introduced in recent works years, they primarily utilize a single type of recurrent neural net (RNNs) and have been implemented in only one deep learning framework. It is unclear how the use of different types of RNNs available in various deep learning frameworks affects the performance of these anomaly detection approaches due to the absence of comprehensive evaluations. Arbitrarily choosing a RNN variant and a deep learning framework to implement an anomaly detection approach may not reflect its true performance and could potentially mislead users into favoring one approach over another. In this paper, we aim to study the influence of various types of RNNs available in popular deep learning frameworks on real-time lightweight time series anomaly detection. We reviewed several state-of-the-art approaches and implemented a representative anomaly detection approach using well-known RNN variants supported by three widely recognized deep learning frameworks. A comprehensive evaluation is then conducted to analyze the performance of each implementation across real-world, open-source time series datasets. The evaluation results provide valuable guidance for selecting the appropriate RNN variant and deep learning framework for real-time, lightweight time series anomaly detection.