Robust decoding and classification of brain patterns measured with electroencephalography (EEG) remains a major challenge for real-world (i.e. outside scientific lab and medical facilities) brain-computer interface (BCI) applications due to well documented inter- and intra-participant variability. Here, we present a large-scale benchmark evaluating over 340,000+ unique combinations of spatial and nonlinear EEG classification. Our methodological pipeline consists in combinations of Common Spatial Patterns (CSP), Riemannian geometry, functional connectivity, and fractal- or entropy-based features across three open-access EEG datasets. Unlike prior studies, our analysis operates at the per-participant level and across multiple frequency bands (8-15 Hz and 8-30 Hz), enabling direct assessment of both group-level performance and individual variability. Covariance tangent space projection (cov-tgsp) and CSP consistently achieved the highest average classification accuracies. However, their effectiveness was strongly dataset-dependent, and marked participant-level differences persisted, particularly in the most heterogeneous of the datasets. Importantly, nonlinear methods outperformed spatial approaches for specific individuals, underscoring the need for personalized pipeline selection. Our findings highlight that no universal 'one-size-fits-all' method can optimally decode EEG motor imagery patterns across all users or datasets. Future work will require adaptive, multimodal, and possibly novel approaches to fully address neurophysiological variability in practical BCI applications where the system can automatically adapt to what makes each user unique.

Non-invasive electroencephalography (EEG)-based brain-computer interfaces (BCIs) offer an intuitive means for individuals with severe motor impairments to independently operate assistive robotic wheelchairs and navigate built environments. Despite considerable progress in BCI research, most current motion control systems are limited to discrete commands, rather than supporting continuous pursuit, where users can freely adjust speed and direction in real time. Such natural mobility control is, however, essential for wheelchair users to navigate complex public spaces, such as transit stations, airports, hospitals, and indoor corridors, to interact socially with the dynamic populations with agility, and to move flexibly and comfortably as autonomous driving is refined to allow movement at will. In this study, we address the gap of continuous pursuit motion control in BCIs by proposing and validating a brain-inspired Bayesian inference framework, where embodied dynamics in acceleration-based motor representations are decoded. This approach contrasts with conventional kinematics-level decoding and deep learning-based methods. Using a public dataset with sixteen hours of EEG from four subjects performing motor imagery-based target-following, we demonstrate that our method, utilizing Automatic Relevance Determination for feature selection and continual online learning, reduces the normalized mean squared error between predicted and true velocities by 72% compared to autoregressive and EEGNet-based methods in a session-accumulative transfer learning setting. Theoretically, these findings empirically support embodied cognition theory and reveal the brain's intrinsic motor control dynamics in an embodied and predictive nature. Practically, grounding EEG decoding in the same dynamical principles that govern biological motion offers a promising path toward more stable and intuitive BCI control.

These authors contributed equally to this work . Abstract: Brain - computer interfaces (BCIs) promise to extend human movement capabilities by enabling direct neural control of supernumerary effectors, yet integrating augmented commands with multi ple degrees of freedom without disrupting natural movement remains a k ey challenge. Here, we propose a tactile - encoded BCI that leverages sensory afferents through a novel tactile - evoked P300 paradigm, allowing intuitive and reliable decoding of supernumerary motor intentions even when superimposed with voluntary actions. The interface was evaluated in a multi - day experiment comprising of a single motor recognition task to validate baseline BCI performance and a dual task paradigm to assess the potential influence between the BCI and natural human movement . T he brain interface achieved real - time and reliable decoding of four supernumerary degrees of freedom, with significant performance improvement s after only three days of training. Importantly, after training, performance did not differ significantly b etween the single - and dual - BCI task conditions, and natural movement remained unimpaired during concurrent supernumerary control . Lastly, the interface was deployed in a movement augmentation task, demonstrating its ability to command two supernumerary robotic arms for functional assistance during bimanual tasks. These results establish a new neural interface paradigm for movement augmentation through stimulation of sensory afferents, expanding motor degrees of fr eedom without impairing natural movement . One - Sentence Summary: T actile - encoded neural interface enables intuitive control of supernumerary limbs without compromising natural human movement Main Text: INTRODUCTION Humans interact with their surroundings with remarkable dexterity and efficiency. Recent advances in robotics and neural interfaces hold the potential to increase these capabilities, enhancing human movement beyond its natural limits. Movement augmentation aims to increase the mechanical degrees of freedom (DoFs) an individual can exert over their surroundings ( 1), allowing movement tasks to be performed more efficiently or enable actions otherwise impossible with natural limbs alone, such as trimanual manipulation with a third arm ( 2) . A central challenge, however, lies in achieving practical control of supernumerary effectors (SEs) without compromising natural movement. Current strategies for augmenting DoFs often rely on augmentation by transfer, in which control of SEs is derived from the function of an existing body part, typically one that is task - irrelevant ( 1, 3, 4) .

Current pain assessment within hospitals often relies on self-reporting or non-specific EKG vital signs. This system leaves critically ill, sedated, and cognitively impaired patients vulnerable to undertreated pain and opioid overuse. Electroencephalography (EEG) offers a noninvasive method of measuring brain activity. This technology could potentially be applied as an assistive tool to highlight nociceptive processing in order to mitigate this issue. In this study, we compared machine learning models for classifying high-pain versus low/no-pain EEG epochs using data from fifty-two healthy adults exposed to laser-evoked pain at three intensities (low, medium, high). Each four-second epoch was transformed into a 537-feature vector spanning spectral power, band ratios, Hjorth parameters, entropy measures, coherence, wavelet energies, and peak-frequency metrics. Nine traditional machine learning models were evaluated with leave-one-participant-out cross-validation. A support vector machine with radial basis function kernel achieved the best offline performance with 88.9% accuracy and sub-millisecond inference time (1.02 ms). Our Feature importance analysis was consistent with current canonical pain physiology, showing contralateral alpha suppression, midline theta/alpha enhancement, and frontal gamma bursts. The real-time XGBoost model maintained an end-to-end latency of about 4 ms and 94.2% accuracy, demonstrating that an EEG-based pain monitor is technically feasible within a clinical setting and provides a pathway towards clinical validation.

This paper presents an Artificial Intelligence (AI) integrated novel approach to Brain - Computer Interface (BCI) - based wheelchair development, utilizing a motor imagery r ight - l eft - h and m ovement mechanism for control. The system is designed to simulate wheelchair navigation based on motor imagery right and left - hand movements using electroencephalogram (EEG) data. A pre - filtered dataset, obtained from an open - source EEG repository, was seg mented into arrays of 19x200 to capture the onset of hand movements. Th e data was acquired at a sampling frequency of 200Hz. The system integrates a Tkinter - based interface for simulating wheelchair movements, offering users a functional and intuitive control system. We propose a BiLSTM - BiGRU model that shows a superior test accuracy of 92. 26 % as compared with v arious machine learning baseline models, including XGBoost, EEGNet, and a transformer - based model . The Bi - LSTM - BiGRU attention - based model achieved a mean accuracy of 90.13 % through cross - validation, showcasing the potential of attention mechanisms in BCI applications. Keywords: Brain Computer Interface (BCI), BiLSTM - BiGRU, Raspberry Pi, E lectroencephalogram (EEG), Hybrid Deep learning 1. Introduction Brain - Computer Interfaces (BCIs) are advanced systems that establish direct communication between the human brain and external devices . In recent years, BCIs have been widely investigated for their potential to assist individuals with mobility impairments, offering novel pathways for restoring autonomy. This paper proposes a BCI - based wheelchair control system driven by electroencephalogra phy (EEG) signals associated with motor imagery. The proposed framework incorporates a variety of machine learning models with tailored hyperparameter optimization techniques, culminating in the deployment of a BiLSTM - BiGRU hybrid deep learning model for effective EEG signal classification.

Classification models used in brain-computer interface (BCI) are usually designed for a single BCI paradigm. This requires the redevelopment of the model when applying it to a new BCI paradigm, resulting in repeated costs and effort. Moreover, less complex deep learning models are desired for practical usage, as well as for deployment on portable devices. In or-der to fill the above gaps, we, in this study, proposed a light-weight and unified decoding model for cross-BCI-paradigm classification. The proposed model starts with a tempo-spatial convolution. It is followed by a multi-scale local feature selec-tion module, aiming to extract local features shared across BCI paradigms and generate weighted features. Finally, a mul-ti-dimensional global feature extraction module is designed, in which multi-dimensional global features are extracted from the weighted features and fused with the weighted features to form high-level feature representations associated with BCI para-digms. The results, evaluated on a mixture of three classical BCI paradigms (i.e., MI, SSVEP, and P300), demon-strate that the proposed model achieves 88.39%, 82.36%, 80.01%, and 0.8092 for accuracy, macro-precision, mac-ro-recall, and macro-F1-score, respectively, significantly out-performing the compared models. This study pro-vides a feasible solution for cross-BCI-paradigm classifica-tion. It lays a technological foundation for de-veloping a new generation of unified decoding systems, paving the way for low-cost and universal practical applications.

This study investigates the application of Riemannian geometry - based methods for brain decoding using invasive electrophysiological recordings. Although previously employed in non - invasive, the utility of Riemannian geometry for invasive datasets, which ar e typically smaller and scarcer, remains less explored. Here, we propose a Minimum Distance to Mean (MDM) classifier using a Riemannian geometry approach based on covariance matrices extracted from intracortical Local Field Potential (LFP) recordings acros s various regions during different brain state dynamics. For benchmarking, we evaluated the performance of our approach against C onvolutional N eural N etworks (CNNs) and Euclidean MDM classifiers. Our results indicate that the Riemannian geometry - based classification not only achieves a superior mean F1 macro - averaged score across different channel configurations but also requires up to two orders of mag nitude less computational training time. Additionally, the geometric framework reveals distinct spatial co ntributions of brain regions across varying brain states, suggesting a state - dependent organization that traditional time series - based methods often fail to capture. Our findings align with previous studies supporting the efficacy of geometry - based methods and extending their application to invasive brain recordings, highlighting their potential for broader clinical use, such as brain computer interface applications.

Like everyone else who got to test Apple's new Vision Pro after its unveiling at the Worldwide Developers Conference in Cupertino, California, this week, I couldn't wait to experience it. But when an Apple technician at the ad hoc test facility used an optical device to check out my prescription lenses, I knew that there might be a problem. The lenses in my spectacles have prisms to address a condition that otherwise gives me double vision. Apple has a set of preground Zeiss lenses to handle most of us who wore glasses, but none could address my problem. In any case, my fears were justified: When I got to the demo room, the setup for eye-tracking--a critical function of the device--didn't work. I was able to experience only a subset of the demos.

The world of computing has witnessed seismic advancements since the invention of the electronic calculator in the 1960s. The past few years in information processing have been especially transformational in our hyper-connected world. Futurist Ray Kurzweil said that mankind will be able to "expand the scope of our intelligence a billion-fold" and that "the power of computing doubles, on average, every two years. Recent breakthroughs in physics, nanotechnologies, and have brought us into a cognitive computing reality that we could not have imagined a decade ago. Biological computing is the advanced science of using biological products to perform actions that would traditionally be done using components like copper wire and fiber glass. Common biological components used in these studies include amino acids and DNA. Computational functions can be performed by manipulating natural chemical reactions found in these substances.

Were you unable to attend Transform 2022? Check out all of the summit sessions in our on-demand library now! Our thoughts are private – or at least they were. New breakthroughs in neuroscience and artificial intelligence are changing that assumption, while at the same time inviting new questions around ethics, privacy, and the horizons of brain/computer interaction. Research published last week from Queen Mary University in London describes an application of a deep neural network that can determine a person's emotional state by analyzing wireless signals that are used like radar.