Can AI Look at Your Retina and Diagnose Alzheimer's? The author of believes AI could bring big changes to the world of medicine. For decades now, it's been fairly well established that once you turn 40 you should start paying more attention to your body. That's when women are supposed to start getting mammograms and men are supposed to start paying a bit more attention to their prostates. Over the next decade, you'll start getting colonoscopies, and from then on out, it feels like a gradual march of doctor's appointments and tests until your body collapses sometime in your seventies or eighties.

Anthropic's Daniela Amodei Believes the Market Will Reward Safe AI The Trump administration might think regulation is killing the AI industry, but Anthropic president Daniela Amodei disagrees. The Trump administration may think regulation is crippling the AI industry, but one of the industry's biggest players doesn't agree. At WIRED's Big Interview event on Thursday, Anthropic president and cofounder Daniela Amodei told WIRED editor at large Steven Levy that even though Trump's AI and crypto czar, David Sacks, may have tweeted that her company is "running a sophisticated regulatory capture strategy based on fear-mongering," she's convinced her company's commitment to calling out the potential dangers of AI is making the industry stronger. WIRED's iconic series returned to San Francisco with a series of unforgettable, in-depth live conversations. Check out more highlights here .

Lisa Su leads Nvidia's biggest rival in the AI chip market. When asked at WIRED's Big Interview event if AI is a bubble, the company's CEO said "Emphatically, from my perspective, no." Earlier this year, WIRED said that AMD CEO Lisa Su was " out for Nvidia's blood ." The American chipmaker is still small compared to the juggernaut that is Nvidia--their market caps are $353 billion and $4.4 trillion, respectively--but Su's company is gaining steam. Today, when Su took the stage at WIRED's Big Interview conference in San Francisco, she had something else in her sights: the AI bubble .

From robot vacuums to Dyson stick vacs, don't miss these Black Friday deals happening on our favorite vacuums in every category. There's a lot of shopping you can do this weekend, but these Black Friday vacuum cleaner deals are ones you shouldn't skip if you need any kind of cleaning upgrade. Changing to a stick vacuum hugely improved my life after moving to a three-story home, but all kinds of vacuum types can turn your life around. Never have time to vacuum or mop? You'll want a handheld vacuum.

In a closed-door workshop led by Anthropic and Stanford, leading AI startups and researchers discussed guidelines for chatbot companions, especially for younger users. At Stanford for eight hours on Monday, representatives from Anthropic, Apple, Google, OpenAI, Meta, and Microsoft met in a closed-door workshop to discuss the use of chatbots as companions or in roleplay scenarios. Interactions with AI tools are often mundane, but they can also lead to dire outcomes. Users sometimes experience mental breakdowns during lengthy conversations with chatbots or confide in them about their suicidal ideations . "We need to have really big conversations across society about what role we want AI to play in our future as humans who are interacting with each other," says Ryn Linthicum, head of user well-being policy at Anthropic .

As OpenAI expands in every direction, the new CEO of Applications is on a mission to make ChatGPT indispensable and lucrative. In case OpenAI's structure couldn't get any weirder--a nonprofit in charge of a for-profit that's become a public benefit corporation--it now has two CEOs. There's Sam Altman, chief executive of the whole company, who manages research and compute. And as of this summer, there's Fidji Simo, the former CEO of Instacart, who manages everything else. Simo hasn't been seen much at OpenAI's San Francisco office since she began as CEO of Applications in August. But her presence is felt at every level of the company--not least because she's heading up ChatGPT and basically every function that might make OpenAI money. Simo is dealing with a relapse of postural orthostatic tachycardia syndrome (POTS) that makes her prone to fainting if she stands for long periods of time. "Being present from 8 am to midnight every day, responding within five minutes, people feel like I'm there and that they can reach me immediately, that I jump on the phone within five minutes," she tells me. Employees confirm that this is true. OpenAI's famously Slack-driven culture can be overwhelming for new hires. Employees say she is often seen popping into channels and threads, sharing thoughts and asking questions.

OpenAI has committed to buying billions of dollars worth of compute from AWS--the latest in a string of major deals brokered by the AI startup. OpenAI has signed a multi-year deal with Amazon to buy $38 billion worth of AWS cloud infrastructure to train its models and serve its users. The deal is yet another sign of the AI industry becoming increasingly entangled, with OpenAI now at the center of major partnerships with industry players including Google, Oracle, Nvidia, and AMD. The AWS agreement is also notable because OpenAI rose to prominence in part through its partnership with Microsoft--Amazon's biggest cloud rival. Amazon is also a major backer of one of OpenAI's key competitors, Anthropic.

Your Friend Asked You a Question. Your friend came to you because they respect your knowledge and opinion, and outsourcing the answer to a machine is lazy and rude. Back in the 2010s, a website called Let Me Google That For You gained a notable amount of popularity for serving a single purpose: snark. The site lets you generate a custom link that you can send somebody who asks you a question. When they click the link, it plays an animation of the process of typing a question into Google.

Mental models play an important role in whether user interaction with intelligent systems, such as dialog systems is successful or not. Adaptive dialog systems present the opportunity to align a dialog agent's behavior with heterogeneous user expectations. However, there has been little research into what mental models users form when interacting with a task-oriented dialog system, how these models affect users' interactions, or what role system adaptation can play in this process, making it challenging to avoid damage to human-AI partnership. In this work, we collect a new publicly available dataset for exploring user mental models about information seeking dialog systems. We demonstrate that users have a variety of conflicting mental models about such systems, the validity of which directly impacts the success of their interactions and perceived usability of system. Furthermore, we show that adapting a dialog agent's behavior to better align with users' mental models, even when done implicitly, can improve perceived usability, dialog efficiency, and success. To this end, we argue that implicit adaptation can be a valid strategy for task-oriented dialog systems, so long as developers first have a solid understanding of users' mental models.

Digitization of business demand a more agile way of operating applications and processes to meet the constantly changing market needs. Unlimited amount of knowledge available at our fingertips and technological advancements are accelerating faster than ever before, thereby blurring lines between physical and digital domains. As we move towards the fourth industrial revolution, looking back at some of the key technological developments in 2019, here's what we can predict for 2020. In 2020, workplace changes related to artificial intelligence (AI) will become a noticeable trend. A recent PwC report revealed that 67 per cent would prefer AI assistance over humans as office assistants.