Alzheimer s disease

This neural network can tell if you're likely to develop Alzheimer's disease in the next three years


Doctors call this mild cognitive impairment, and it affects most people as they get older. Certain types of PET scans can reveal signs of both these conditions and can therefore be used to spot people with mild cognitive impairment who are most at risk of developing Alzheimer's. This data set consists of brain images of 182 people in their 70s with normal brains and brain images of 139 people of roughly the same age who have been diagnosed with Alzheimer's. Hongyoon and Kyong say their neural network identified those at risk of developing Alzheimer's with an accuracy of 81 percent.

Putting a computer in your brain is no longer science fiction

AITopics Original Links

Like many in Silicon Valley, technology entrepreneur Bryan Johnson sees a future in which intelligent machines can do things like drive cars on their own and anticipate our needs before we ask. What's uncommon is how Johnson wants to respond: find a way to supercharge the human brain so that we can keep up with the machines. From an unassuming office in Venice Beach, his science-fiction-meets-science start-up, Kernel, is building a tiny chip that can be implanted in the brain to help people suffering from neurological damage caused by strokes, Alzheimer's or concussions. Top neuroscientists who are building the chip -- they call it a neuroprosthetic -- hope that in the longer term, it will be able to boost intelligence, memory and other cognitive tasks. The medical device is years in the making, Johnson acknowledges, but he can afford the time.

Human brains 'file' irrelevant thoughts of the past into a 'trash folder'

Daily Mail

Vital clues about how the brain erases long-term memories have been uncovered by researchers. The study reveals how forgetting can be the result of an'active deletion process' - similar to moving a computer file to a virtual bin - rather than a failure to remember. And the findings may help point towards new ways of tackling memory loss associated with conditions such as Alzheimer's disease and other types of dementia. A study has revealed how forgetting memories can be the result of an'active deletion process' - similar to moving a computer file to a virtual bin - rather than a failure to remember. The findings could also help scientists to understand why some unwanted memories are so long-lasting - such as those of people suffering from post-traumatic stress disorders.

Who Will Be First To "Hack The Code" Of Aging?

Popular Science

In 2014, Joon Yun, founder of the Palo Alto Institute in California, announced the 1 million Palo Alto Longevity Prize. So far, 30 teams from across the world have signed up to compete, including research groups at schools such as Stanford University and the University of Nebraska Medical Center, and teams from the private sector, such as Volt Health, led by a medical-device designer. It's brought firepower to the effort: Calico's leaders include former heads of drug companies and top-notch experts on genomics and aging. Map based on data from the Institute for Health Metrics and Evaluation--Popular Science combined figures for women and men to obtain a total average life expectancy at birth.

"Lost" memories can be found

MIT News

In the early stages of Alzheimer's disease, patients are often unable to remember recent experiences. Whenever these tagged engram cells are activated by light, normal mice recall the memory encoded by that group of cells. Likewise, when the researchers placed the Alzheimer's mice in a chamber they had never seen before and shined light on the engram cells encoding the fearful experience, the mice immediately showed fear. "It's possible that in the future some technology will be developed to activate or inactivate cells deep inside the brain, like the hippocampus or entorhinal cortex, with more precision," Tonegawa says.

Scientists find and restore lost memories by 'flicking a light switch' in the brain

Daily Mail

They can be traumatic, joyful and sometimes hard to remember but memories play a significant role in who we are and how we think. Now, scientists have developed a technique that not only pinpoints memories in the brain, to reveal what they look like, it can be used to restore thoughts that have been lost. The research additionally shows that patients with Alzheimer's may not have problems encoding memories, and instead the fault lies in retrieving the memory instead. This image reveals what a memory looks like. It depicts a memory engram cell (green) in the hippocampal dentate gyrus (DG) region of a mouse brain with symptoms similar to Alzheimer's disease.

Older adults buddy up with Amazon's Alexa


Among the more than 30,000 customer reviews on the Amazon website are those from caregivers for wheelchair-bound relatives who love the control that Alexa gives them over their environment, and also from family members of older adults who enjoy Alexa's companionship and help. Gentry recognizes Alexa's promise to alleviate loneliness in older adults and plans to test the device with some of his elderly clients soon. Developed by one of the third-party firms that Amazon has invited to create "skills" for Alexa, this function can send phone calls or text messages to up to five contacts. A user would say, "Alexa, ask my buddy Bob to send help" and Bob would get an alert to check in on his friend.