What is the'correct' theoretical description of neuronal activity? The analysis of the dynamics of a globally connected network of spiking neurons (the Spike Response Model) shows that a description bymean firing rates is possible only if active neurons fire incoherently. Iffiring occurs coherently or with spatiotemporal correlations, the spike structure of the neural code becomes relevant. Alternatively, neurons can be gathered into local or distributed ensembles or'assemblies'. A description based on the mean ensemble activity is, in principle, possible but the interaction between different assembliesbecomes highly nonlinear. A description with spikes should therefore be preferred.

Thomas G. Dietterich Arris Pharmaceutical Corporation and Oregon State University Corvallis, OR 97331-3202 Ajay N. Jain Arris Pharmaceutical Corporation 385 Oyster Point Blvd., Suite 3 South San Francisco, CA 94080 Richard H. Lathrop and Tomas Lozano-Perez Arris Pharmaceutical Corporation and MIT Artificial Intelligence Laboratory 545 Technology Square Cambridge, MA 02139 Abstract In drug activity prediction (as in handwritten character recognition), thefeatures extracted to describe a training example depend on the pose (location, orientation, etc.) of the example. In handwritten characterrecognition, one of the best techniques for addressing thisproblem is the tangent distance method of Simard, LeCun and Denker (1993). Jain, et al. (1993a; 1993b) introduce a new technique-dynamic reposing-that also addresses this problem. Dynamicreposing iteratively learns a neural network and then reposes the examples in an effort to maximize the predicted output values.New models are trained and new poses computed until models and poses converge. This paper compares dynamic reposing to the tangent distance method on the task of predicting the biological activityof musk compounds.

This paper introduces a new recognition-based segmentation approach torecognizing online cursive handwriting from a database of 10,000 English words. The original input stream of z, y pen coordinates isencoded as a sequence of uniform stroke descriptions that are processed by six feed-forward neural-networks, each designed to recognize letters of different sizes. Words are then recognized by performing best-first search over the space of all possible segmentations. Resultsdemonstrate that the method is effective at both writer dependent recognition (1.7% to 15.5% error rate) and writer independent recognition (5.2% to 31.1% error rate). 1 Introduction With the advent of pen-based computers, the problem of automatically recognizing handwriting from the motions of a pen has gained much significance. Progress has been made in reading disjoint block letters [Weissman et.

Sound localization by the barn owl (tyto alba) measured with the search coil technique.

Integrated Mean Squared Error (IMSE) is a version of the usual mean squared error criterion, averaged over all possible training sets of a given size. If it could be observed, it could be used to determine optimal network complexity or optimal data subsets forefficient training. We show that two common methods of cross-validating average squared error deliver unbiased estimates of IMSE, converging to IMSE with probability one. We also show that two variants of cross validation measure provide unbiased IMSE-based estimates potentially useful for selecting optimal data subsets. 1 Summary To begin, assume we are given a fixed network architecture. Let zN denote a given set of N training examples.

A.C.C. Coolen R.W. Penney D. Sherrington Dept. of Physics - Theoretical Physics University of Oxford 1 Keble Road, Oxford OXI 3NP, U.K. Abstract A simple model of coupled dynamics of fast neurons and slow interactions, modellingself-organization in recurrent neural networks, leads naturally to an effective statistical mechanics characterized by a partition function which is an average over a replicated system. This is reminiscent of the replica trick used to study spin-glasses, but with the difference that the number of replicas has a physical meaningas the ratio of two temperatures and can be varied throughout the whole range of real values. The model has interesting phaseconsequences as a function of varying this ratio and external stimuli, and can be extended to a range of other models. 1 A SIMPLE MODEL WITH FAST DYNAMIC NEURONS AND SLOW DYNAMIC INTERACTIONS As the basic archetypal model we consider a system of Ising spin neurons (J'i E {-I, I}, i E {I, ..., N}, interacting via continuous-valued symmetric interactions, Iij, which themselves evolve in response to the states of the neurons. The neurons are taken to have a stochastic field-alignment dynamics which is fast compared with the evolution rate of the interactions hj, such that on the timescale of Iii-dynamics the neurons are effectively in equilibrium according to a Boltzmann distribution, (1) 447 448 Cooien, Penney, and Sherrington where HVoj}({O"d) JijO"iO"j (2) i j and the subscript {Jij} indicates that the {Jij} are to be considered as quenched variables. In practice, several specific types of dynamics which obey detailed balance lead to the equilibrium distribution (1), such as a Markov process with single-spin flip Glauber dynamics [1]. The second term acts to limit the magnitude of hj; f3 is the characteristic inverse temperature of the interaction system. VNTJij(t) (4) where the effective Hamiltonian 11. ({ hj}) is given by 1 1 We now recognise (4) as having the form of a Langevin equation, so that the equilibrium distributionof the interaction system is given by a Boltzmann form. Z{3 (6) Coupled Dynamics of Fast Neurons and Slow Interactions 449 where n _ /j3. We may use Z as a generating functional to produce thermodynamic averagesof state variables I ( {O"d; {Jij}) in the combined system by adding suitable infinitesimal source terms to the neuron Hamiltonian (2): HP.j}({O"d) In fact, any real n is possible by tuning the ratio between the two {3's. In the formulation presented in this paper n is always nonnegative, but negative values are possible if the Hebbian rule of (3) is replaced by an anti-Hebbian form with (UiO"j) replaced by - (O"iO"j) (the case of negative n is being studied by Mezard and coworkers [7]).

EE., Linkoping University S-58183 Linkoping Sweden Abstract We describe a number of learning rules that can be used to train unsupervised parallelfeature extraction systems. The learning rules are derived using gradient ascent of a quality function. We consider anumber of quality functions that are rational functions of higher order moments of the extracted feature values. We show that one system learns the principle components of the correlation matrix.Principal component analysis systems are usually not optimal feature extractors for classification. Therefore we design quality functions which produce feature vectors that support unsupervised classification.The properties of the different systems are compared with the help of different artificially designed datasets and a database consisting of all Munsell color spectra. 1 Introduction There are a number of unsupervised Hebbian learning algorithms (see Oja, 1992 and references therein) that perform some version of the Karhunen-Loeve expansion.

We address the problem of optical flow reconstruction and in particular theproblem of resolving ambiguities near edges. They occur due to (i) the aperture problem and (ii) the occlusion problem, where pixels on both sides of an intensity edge are assigned the same velocity estimates (and confidence). However, these measurements are correct for just one side of the edge (the non occluded one). Our approach is to introduce an uncertamty field with respect to the estimates and confidence measures. We note that the confidence measuresare large at intensity edges and larger at the convex sides of the edges, i.e. inside corners, than at the concave side. We resolve the ambiguities through local interactions via coupled Markov random fields (MRF). The result is the detection of motion for regions of images with large global convexity.

Center positions are continuously updated through soft competitive learning. The width of the radial basis functions is derived from the distance to topological neighbors. During the training the observed error is accumulated locally and used to determine where to insert the next unit. This leads (in case of classification problems) to the placement of units near class borders rather than near frequency peaks as is done by most existing methods. The resulting networks need few training epochs and seem to generalize very well. This is demonstrated by examples.

We propose a trajectory planning and control theory for continuous movements such as connected cursive handwriting and continuous natural speech. Its hardware is based on our previously proposed forward-inverse-relaxation neural network (Wada & Kawato, 1993). Computationally, its optimization principle is the minimum torquechange criterion.Regarding the representation level, hard constraints satisfied by a trajectory are represented as a set of via-points extracted from a handwritten character. Accordingly, we propose a via-point estimation algorithm that estimates via-points by repeating the trajectory formation of a character and the via-point extraction from the character. In experiments, good quantitative agreement is found between human handwriting data and the trajectories generated by the theory. Finally, we propose a recognition schema based on the movement generation. We show a result in which the recognition schema is applied to the handwritten character recognition and can be extended to the phoneme timing estimation of natural speech. 1 INTRODUCTION In reaching movements, trajectory formation is an ill-posed problem because the hand can move along an infinite number of possible trajectories from the starting to the target point.