The specific motivations underlying this research include the following propositions: (1) Reasoning from experimental evidence contained in the clinical literature is central to the decisions physicians make in patient care. Furthermore, the model can help us better understand the general principles of reasoning from experimental evidence both in medicine and other domains. Roundsman is a developmental computer system that draws on structured representations of the clinical literature to critique plans for the management of primary breast cancer. Roundsman is able to produce patient-specific analyses of breast cancer-management options based on the 24 clinical studies currently encoded in its knowledge base.

A panel session at the 1989 International Joint Conference on artificial intelligence in Los Angeles dealt with the subject of knowledge-based systems; the session was entitled "Expert Systems: How Far Can They Go?" The panelists included Randall Davis (Massachusetts Institute of Technology); Stuart Dreyfus (University of California at Berkeley); Brian Smith (Xerox Palo Alto Research Center); and Terry Winograd (Stanford University), chairman. Part 1 includes presentations from Winograd and Dreyfus. Part 2, which will appear in the Summer 1989 issue, includes presentations from Smith and Davis and concludes with the panel discussion.

Robert K. Levin, Diane E. Drang, and Barry Edelson's book might better be titled, an introduction to expert systems: Turbo Pascal edition. THe book does not live up to the promise implied in the title.

Artificial Intelligence is solving more and more real world problems, but penetration into the complexities of government administration has been minimal. The author suggests that combining expert system technology with conventional procedural computer systems can lead to substantial efficiencies. Business rules can be removed from business-oriented computer systems and stored in a separate but integrated knowledge base, where maintenance will be centralized. Fourteen specific practical applications are suggested.

TOWARDS AN ORGANIZING PRINCIPLE FOR A LAYERED PERCEPTUAL NETWORK Ralph Linsker IBM Thomas J. Watson Research Center, Yorktown Heights, NY 10598 Abstract An information-theoretic optimization principle is proposed for the development of each processing stage of a multilayered perceptual network. This principle of "maximum information preservation" states that the signal transformation that is to be realized at each stage is one that maximizes the information that the output signal values (from that stage) convey about the input signals values (to that stage), subject to certain constraints and in the presence of processing noise. The quantity being maximized is a Shannon information rate. I provide motivation for this principle and -- for some simple model cases -- derive some of its consequences, discuss an algorithmic implementation, and show how the principle may lead to biologically relevant neural architectural features such as topographic maps, map distortions, orientation selectivity, and extraction of spatial and temporal signal correlations. A possible connection between this information-theoretic principle and a principle of minimum entropy production in nonequilibrium thermodynamics is suggested. Introduction This paper describes some properties of a proposed information-theoretic organizing principle for the development of a layered perceptual network.

We built on previous work to develop an evaluation method that can be used to select expert system applications which are most likely to be successfully implemented. Both essential and desirable features of an expert system application are discussed. Essential features are used to ensure that the application does not require technology beyond the state of the art. Advice on helpful directions for evaluating candidate expert system applications is also given.

A novel approach is presented for the development of expert systems for structural design problems. This approach differs from the conventional expert systems in two fundamental respects. As an example of this approach, a prototype coupled expert system, the bridge truss expert (BTExpert), is presented for optimum design of bridge trusses subjected to moving loads. BTExpert was developed by interfacing an interactive optimization program developed in Fortran 77 to an expert system shell developed in Pascal.

The PROSENET/TEXTNET approach is designed to facilitate the generation of polished prose by an expert system. The approach uses the augmented transition network (ATN) formalism to help structure prose generation at the phrase, sentence, and paragraph levels. The approach also uses expressive frames to help give the expert system builder considerable freedom to organize material flexibly at the paragraph level. The PROSENET /TEXTNET approach has been used in a number of prototype expert systems in medical domains, and has proved to be a convenient and powerful tool.

The goal of intelligent computer-aided engineering (ICAE) is to construct computer programs that capture a significant fraction of an engineer's knowledge. Today, ICAE systems are a goal, not a reality. We begin by examining several scenarios of what ICAE systems could be like. Next we describe why ICAE won't evolve directly from current applications of expert system technology to engineering problems.

Within the academic and professional auditing communities, there has been growing concern about how to accurately assess the various risks associated with performing an audit. These risks are difficult to conceptualize in terms of numeric estimates.