Bayesian Regularization and Nonnegative Deconvolution (BRAND) is proposed for estimating time delays of acoustic signals in reverberant environments. Sparsity of the nonnegative filter coefficients is enforced using an L -norm regularization.

We study the synthesis of neural coding, selective attention and perceptual decision making. A hierarchical neural architecture is proposed, which implements Bayesian integration of noisy sensory input and top-down attentional priors, leading to sound perceptual discrimination. The model offers an explicit explanation for the experimentally observed modulation that prior information in one stimulus feature (location) can have on an independent feature (orientation). The network's intermediate levels of representation instantiate known physiological properties of visual cortical neurons. The model also illustrates a possible reconciliation of cortical and neuromodulatory representations of uncertainty.

In this paper, we explore the use of Random Forests (RFs) in the structured languagemodel (SLM), which uses rich syntactic information in predicting the next word based on words already seen. The goal in this work is to construct RFs by randomly growing Decision Trees (DTs) using syntacticinformation and investigate the performance of the SLM modeled by the RFs in automatic speech recognition. RFs, which were originally developed as classifiers, are a combination of decision tree classifiers. Each tree is grown based on random training data sampled independently and with the same distribution for all trees in the forest, and a random selection of possible questions at each node of the decision tree. Our approach extends the original idea of RFs to deal with the data sparseness problem encountered in language modeling. RFs have been studied in the context of n-gram language modeling and have been shown to generalize well to unseen data. We show in this paper that RFs using syntactic information can also achieve better performance in both perplexity (PPL) and word error rate (WER) in a large vocabulary speech recognition system, compared to a baseline that uses Kneser-Ney smoothing.

Complex objects can often be conveniently represented by finite sets of simpler components, such as images by sets of patches or texts by bags of words. We study the class of positive definite (p.d.) kernels for two such objects that can be expressed as a function of the merger of their respective sets of components. We prove a general integral representation ofsuch kernels and present two particular examples. One of them leads to a kernel for sets of points living in a space endowed itself with a positive definite kernel. We provide experimental results on a benchmark experiment of handwritten digits image classification which illustrate the validity of the approach.

We present a novel method for learning with Gaussian process regression ina hierarchical Bayesian framework. In a first step, kernel matrices on a fixed set of input points are learned from data using a simple and efficient EM algorithm. This step is nonparametric, in that it does not require a parametric form of covariance function. In a second step, kernel functions are fitted to approximate the learned covariance matrix using a generalized Nyström method, which results in a complex, data driven kernel. We evaluate our approach as a recommendation engine for art images, where the proposed hierarchical Bayesian method leads to excellent prediction performance.

We abstract out the core search problem of active learning schemes, to better understand the extent to which adaptive labeling can improve sample complexity.We give various upper and lower bounds on the number of labels which need to be queried, and we prove that a popular greedy active learning rule is approximately as good as any other strategy for minimizing this number of labels.

X-ray crystallography is currently the most common way protein structures are elucidated. One of the most time-consuming steps in the crystallographic process is interpretation of the electron density map, a task that involves finding patterns in a three-dimensional picture of a protein. This paper describes DEFT (DEFormable Template), an algorithm using pictorial structures to build a flexible protein model from the protein's amino-acid sequence. Matching this pictorial structure into the density map is a way of automating density-map interpretation. Also described are several extensions to the pictorial structure matching algorithm necessary for this automated interpretation. DEFT is tested on a set of density maps ranging from 2 to 4Å resolution, producing rootmean-squared errors ranging from 1.38 to 1.84Å.

Device mismatch in VLSI degrades the accuracy of analog arithmetic circuits and lowers the learning performance of large-scale neural networks implemented in this technology. We show compact, low-power on-chip calibration techniques that compensate for device mismatch. Our techniques enable large-scale analog VLSI neural networks with learning performance on the order of 10 bits. We demonstrate our techniques on a 64-synapse linear perceptron learning with the Least-Mean-Squares (LMS) algorithm, and fabricated in a 0.35µm CMOS process.

A graph-based prior is proposed for parametric semi-supervised classification. The prior utilizes both labelled and unlabelled data; it also integrates features from multiple views of a given sample (e.g., multiple sensors), thus implementing a Bayesian form of co-training. An EM algorithm for training the classifier automatically adjusts the tradeoff between the contributions of: (a) the labelled data; (b) the unlabelled data; and (c) the co-training information. Active label query selection is performed using a mutual information based criterion that explicitly uses the unlabelled data and the co-training information. Encouraging results are presented on public benchmarks and on measured data from single and multiple sensors.

We describe an approach to building brain-computer interfaces (BCI) based on graphical models for probabilistic inference and learning. We show how a dynamic Bayesian network (DBN) can be used to infer probability distributions over brain-and body-states during planning and execution of actions. The DBN is learned directly from observed data and allows measured signals such as EEG and EMG to be interpreted in terms of internal states such as intent to move, preparatory activity, and movement execution. Unlike traditional classification-based approaches to BCI, the proposed approach (1) allows continuous tracking and prediction of internal states over time, and (2) generates control signals based on an entire probability distribution over states rather than binary yes/no decisions. We present preliminary results of brain-and body-state estimation using simultaneous EEG and EMG signals recorded during a self-paced left/right hand movement task.