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Japan Approves the World's First Treatment Made With Reprogrammed Human Cells

WIRED

Japan Approves the World's First Treatment Made With Reprogrammed Human Cells Researchers in Japan pioneered reprogrammed cells 20 years ago. Now the country has given the first-ever authorizations to manufacture and sell medical products based on the technology. Human iPS cell colony established from fibroblasts. Its actual width is approximately 0.5 mm. On March 6, Japan's Ministry of Health, Labor and Welfare officially granted conditional and time-limited marketing authorization to two regenerative medical products derived from reprogrammed iPS cells, marking exactly 20 years since the creation of mouse iPS cells .


'Kill the people': How men were left to starve in a South African gold mine

Al Jazeera

How men were left to starve in a South African gold mine. This image was created by Mohamed Hussein using the artificial intelligence (AI) tool Midjourney. Ayanda Ndabeni watched the faint glow from his headlamp fight the vast darkness 1,500 metres (4,920 feet) below ground. His miner's lamp had lasted for more than a week after he was lowered down into the shaft of the gold mine. But now the batteries were dying. He gently flipped the plastic switch of his lamp, turning it off, and the trapped men around him became shadows. In the stifling heat and humidity, their anxiety pressed in from all sides. Ayanda had descended into Shaft 10 of the Buffelsfontein mine in late September 2024, lowered by a team of nearly 20 men operating ropes and a pulley above ground. That day, he'd spotted police vehicles near the mine's entrance. The 36-year-old assumed it was just routine patrols around the mine system, which is 2km (1.2 miles) deep. But then the rope pulley, via which food, water, batteries and other items arrived, stopped moving. The shouting that usually indicated the rope operators were sending down a man or supplies also fell silent. When huge rocks came crashing down the shaft, they knew it was a warning. The men whispered of their growing fears that something was very wrong on the surface. Patrick Ntsokolo was also in Shaft 10. He was a few hundred metres higher up than Ayanda and had arrived in late July. Patrick was new to the mines. Tasked by the leaders of the artisanal miners with collecting the food, water and alcohol lowered down by the rope pulley, he hauled supplies along the slippery tunnels to small shops.



Meat showered from the sky in Kentucky 150 years ago. Now scientists finally think they know why

Daily Mail - Science & tech

Queen Camilla told her friend that Meghan Markle'brainwashed' Prince Harry, new book claims Ground stop issued for all three Washington DC-area airports after'strong chemical smell' detected Uncomfortable truth about what happened to Rob Reiner's forgotten daughter Tracy: As she breaks cover for first time since murders... new details of secret New Mexico life Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Ohio mom's agony as National Guard member, 28, named as one of six Americans killed in Iraq crash Dak Prescott's crippling secret fear: Quarterback'preparing for the worst' after fiancée split... as career-ending gossip now seems inevitable Mysterious'Trump' airships appearing in 100-year-old sketchbooks sparks'time traveler' theories Downfall of Trump VP hopeful exiled to construction job: Filthy messages, Oval Office humiliations and the Ice Maiden who'f***ing hates his guts' What convinced Timothy Busfield's wife Melissa Gilbert that he didn't grope children: 'She would dump his a**' Woke Seattle writer claims she's no longer devastated by husband's demand for open marriage after she had threesome with him and his girlfriend Inside the sex guide electrifying conservative women: Good Christian wives purring over'explicit illustrations' that teach them the ultimate taboos Trump hails dramatic bombing raid on'Iran's crown jewel'... but says one area deliberately SPARED: Live updates AMANDA PLATELL: Meghan had the world at her feet. Now I feel reality is finally dawning on her and Harry. Princess Anne's secret phone call to Andrew, how she reacted to his arrest... and surprising offer she made to him: Insiders tell RICHARD KAY her hidden role as the Epstein crisis engulfed the royals - and what she thinks of Kate'I was in love with him': Woman who had years-long romance with Timothee Chalamet says he blindsided her with Kylie Jenner relationship Pieces of raw meat suddenly began falling from the sky over rural Kentucky, baffling witnesses who watched the bizarre shower unfold beneath a clear blue sky. The strange incident occurred on farmland owned by Allen and Rebecca Crouch on March 3, 1876. Witnesses said chunks of meat continued to fall from the sky for several minutes, scattering across an area roughly 100 yards long and 50 yards wide.


Watch: Why Kharg Island is a lifeline for Iran

BBC News

Kharg Island is a small rocky outcrop just 15 miles (24km) off the coast of Iran - but despite its size, it is one of the most critical pieces of Iran's energy infrastructure. US President Donald Trump recently posted on Truth Social that the US military had conducted what he called one of the most powerful bombing raids in the history of the Middle East, obliterating every military target on the island. BBC Security Brief's Mikey Kay breaks down why Kharg Island is a lifeline for Iran, and why it is so strategically important for the US. As turmoil continues in the Middle East, the price of crude oil rose to more than $100 a barrel on Monday. Watch: Ukrainian anti-drone'bullet' that could help defend Gulf The BBC's Diplomatic Correspondent, James Landale, is in Ukraine to see the latest anti-drone technology the country has to offer.


Meta reportedly plans sweeping layoffs as AI costs increase

The Guardian

Meta is planning sweeping layoffs that could affect 20% or more of the company, three sources familiar with the matter told Reuters, as Meta seeks to offset costly artificial intelligence infrastructure bets and prepare for greater efficiency brought about by AI-assisted workers. No date has been set for the cuts and the magnitude has not been finalized, the people said. Top executives have recently signaled the plans to other senior leaders at Meta and told them to begin planning how to pare back, two of the people said. The sources spoke anonymously because they were not authorized to disclose the cuts. Meta did not immediately comment.


Is Dubai's glossy image under threat? Not everyone thinks so

BBC News

Is Dubai's glossy image under threat? Stephanie Baker had been celebrating her birthday with friends at a bar on Palm Jumeirah - Dubai's iconic man-made palm-shaped island lined with luxury hotels and beach clubs. But as the group stepped outside to head to another nearby venue, something unusual streaked across the night sky. Moments later, debris from a drone struck the five-star Fairmont hotel - Baker and her friends were standing right across the street. We all were scared, she says.


Forget Viagra! 'Arousal training' app can help men last TWICE as long in bed, scientists say

Daily Mail - Science & tech

Ground stop issued for all three Washington DC-area airports after'strong chemical smell' detected Trump hails dramatic bombing raid on'Iran's crown jewel'... but says one area deliberately SPARED: Live updates Uncomfortable truth about what happened to Rob Reiner's forgotten daughter Tracy: As she breaks cover for first time since murders... new details of secret New Mexico life Kylie Jenner's total humiliation in Hollywood: Derogatory rumor leaves her boyfriend's peers'laughing at her' behind her back Dak Prescott's crippling secret fear: Quarterback'preparing for the worst' after fiancée split... as career-ending gossip now seems inevitable Queen Camilla told her friend that Meghan Markle'brainwashed' Prince Harry, new book claims Downfall of Trump VP hopeful exiled to construction job: Filthy messages, Oval Office humiliations and the Ice Maiden who'f***ing hates his guts' What convinced Timothy Busfield's wife Melissa Gilbert that he didn't grope children: 'She would dump his a**' Mysterious'Trump' airships appearing in 100-year-old sketchbooks sparks'time traveler' theories Yellowstone fans go wild as Cole Hauser unveils spinoff series Dutton Ranch: 'Here we go!' Men admit their wildest kinks to JANA HOCKING: Some are smelly, some are truly shocking... but these are the ones women actually secretly adore Inside the sex guide electrifying conservative women: Good Christian wives purring over'explicit illustrations' that teach them the ultimate taboos Liberal MS NOW star makes prediction about Gavin Newsom's 2028 chances that will ENRAGE California governor Dolly Parton, 80, makes first public appearance in MONTHS as she admits to getting'worn out' amid health struggles Forget Viagra! 'Arousal training' app can help men last TWICE as long in bed, scientists say Forget Viagra! 'Arousal training' app can help men last TWICE as long in bed, scientists say An'arousal training' app could help men last twice as long in bed, a study has found. The Melonga App guides users through a number of therapeutic techniques, tips and exercises designed by urologists and psychologists. It is designed to help men manage arousal better and includes elements of cognitive behavioural therapy and physical exercises to improve ejaculation control without taking medicine. The at-home self-help tool could benefit men who are hesitant to seek help because they are ashamed, researchers said. And it could help the 20 to 30 per cent of men in the UK who are estimated to suffer from the issue, which is defined by ejaculating sooner than wanted during sex.


How to stop your soda from exploding, according to science

Popular Science

You don't want a soda bath. Breakthroughs, discoveries, and DIY tips sent six days a week. Picture this: You're at a picnic on a hot day and grab a cold Coke out of the cooler. It's wet, you drop it, but think "eh, it's fine." You pop the can open and SPLASH--there's soda all over white shirt.


Oscars security tighter than ever: 1-mile police buffer amid Iran war

Los Angeles Times

Things to Do in L.A. Tap to enable a layout that focuses on the article. Workers move a decorative replica Oscar statue as preparations are made on the red carpet arrivals area ahead of the 98th Academy Awards in Hollywood on Friday. This is read by an automated voice. Please report any issues or inconsistencies here . It's been more than two decades since the Oscars were celebrated as the United States was launching a war in the Middle East.