Model Predictive Control was developed in the late 70's and came into widespread use, particularly in the refining industry, in the 80's. The economic benefit of this approach to control has been documented [1,2] .

Previous biophysical modeling work showed that nonlinear interactions amongnearby synapses located on active dendritic trees can provide a large boost in the memory capacity of a cell (Mel, 1992a, 1992b).

Local "belief propagation" rules of the sort proposed by Pearl [15] are guaranteed to converge to the correct posterior probabilities in singly connected graphical models. Recently, a number of researchers have empirically demonstratedgood performance of "loopy belief propagation" using these same rules on graphs with loops. Perhaps the most dramatic instance is the near Shannon-limit performance of "Turbo codes", whose decoding algorithm is equivalent to loopy belief propagation. Except for the case of graphs with a single loop, there has been little theoretical understandingof the performance of loopy propagation. Here we analyze belief propagation in networks with arbitrary topologies when the nodes in the graph describe jointly Gaussian random variables.

The nonnegative Boltzmann machine (NNBM) is a recurrent neural network modelthat can describe multimodal nonnegative data. Application ofmaximum likelihood estimation to this model gives a learning rule that is analogous to the binary Boltzmann machine. We examine the utility of the mean field approximation for the NNBM, and describe how Monte Carlo sampling techniques can be used to learn its parameters. Reflective slicesampling is particularly well-suited for this distribution, and can efficiently be implemented to sample the distribution. We illustrate learning of the NNBM on a transiationally invariant distribution, as well as on a generative model for images of human faces. Introduction The multivariate Gaussian is the most elementary distribution used to model generic data.

The idea of a large minimum margin [17] explains the good generalization performance of AdaBoost in the low noise regime. However, AdaBoost performs worse on noisy tasks [10, 11], such as the iris and the breast cancer benchmark data sets [1]. On the latter tasks, a large margin on all training points cannot be achieved without adverse effects on the generalization error. This experimental observation was supported by the study of [13] where the generalization error of ensemble methods was bounded by the sum of the fraction of training points which have a margin smaller than some value p, say, plus a complexity term depending on the base hypotheses and p. While this bound can only capture part of what is going on in practice, it nevertheless already conveys the message that in some cases it pays to allow for some points which have a small margin, or are misclassified, if this leads to a larger overall margin on the remaining points. To cope with this problem, it was mandatory to construct regularized variants of AdaBoost, which traded off the number of margin errors and the size of the margin 562 G. Riitsch, B. Sch6lkopf, A. J. Smola, K.-R.

I present a simple variation of importance sampling that explicitly searches forimportant regions in the target distribution. I prove that the technique yieldsunbiased estimates, and show empirically it can reduce the variance of standard Monte Carlo estimators. This is achieved by concentrating samplesin more significant regions of the sample space. 1 Introduction It is well known that general inference and learning with graphical models is computationally hard[1] and it is therefore necessary to consider restricted architectures [13], or approximate algorithms to perform these tasks [3, 7]. Among the most convenient and successful techniques are stochastic methods which are guaranteed to converge to a correct solution in the limit oflarge samples [10, 11, 12, 15]. These methods can be easily applied to complex inference problems that overwhelm deterministic approaches.

Dual estimation refers to the problem of simultaneously estimating the state of a dynamic system and the model which gives rise to the dynamics.

We provide an analysis of the turbo decoding algorithm (TDA) in a setting involving Gaussian densities. In this context, we are able to show that the algorithm converges and that - somewhat surprisingly - though the density generated by the TDA may differ significantly from the desired posterior density, the means of these two densities coincide.

We develop a hierarchical generative model to study cue combination. The model maps a global shape parameter to local cuespecific parameters, which in tum generate an intensity image. Inferring shape from images is achieved by inverting this model. Inference produces a probability distribution at each level; using distributions rather than a single value of underlying variables at each stage preserves information about the validity of each local cue for the given image. This allows the model, unlike standard combination models, to adaptively weight each cue based on general cue reliability and specific image context.

We have developed and tested an analog/digital VLSI system that models thecoordination of biological segmental oscillators underlying axial locomotion in animals such as leeches and lampreys. In its current form the system consists of a chain of twelve pattern generating circuits that are capable of arbitrary contralateral inhibitory synaptic coupling. Each pattern generating circuit is implemented with two independent silicon Morris-Lecar neurons with a total of 32 programmable (floating-gate based) inhibitory synapses, and an asynchronous address-event interconnection elementthat provides synaptic connectivity and implements axonal delay. We describe and analyze the data from a set of experiments exploringthe system behavior in terms of synaptic coupling.