Time-resolved CBCT imaging, which reconstructs a dynamic sequence of CBCTs reflecting intra-scan motion (one CBCT per x-ray projection without phase sorting or binning), is highly desired for regular and irregular motion characterization, patient setup, and motion-adapted radiotherapy. Representing patient anatomy and associated motion fields as 3D Gaussians, we developed a Gaussian representation-based framework (PMF-STGR) for fast and accurate dynamic CBCT reconstruction. PMF-STGR comprises three major components: a dense set of 3D Gaussians to reconstruct a reference-frame CBCT for the dynamic sequence; another 3D Gaussian set to capture three-level, coarse-to-fine motion-basis-components (MBCs) to model the intra-scan motion; and a CNN-based motion encoder to solve projection-specific temporal coefficients for the MBCs. Scaled by the temporal coefficients, the learned MBCs will combine into deformation vector fields to deform the reference CBCT into projection-specific, time-resolved CBCTs to capture the dynamic motion. Due to the strong representation power of 3D Gaussians, PMF-STGR can reconstruct dynamic CBCTs in a 'one-shot' training fashion from a standard 3D CBCT scan, without using any prior anatomical or motion model. We evaluated PMF-STGR using XCAT phantom simulations and real patient scans. Metrics including the image relative error, structural-similarity-index-measure, tumor center-of-mass-error, and landmark localization error were used to evaluate the accuracy of solved dynamic CBCTs and motion. PMF-STGR shows clear advantages over a state-of-the-art, INR-based approach, PMF-STINR. Compared with PMF-STINR, PMF-STGR reduces reconstruction time by 50% while reconstructing less blurred images with better motion accuracy. With improved efficiency and accuracy, PMF-STGR enhances the applicability of dynamic CBCT imaging for potential clinical translation.

Current neural networks often employ multi-domain-learning or attribute-injecting mechanisms to incorporate non-independent and identically distributed (non-IID) information for text understanding tasks by capturing individual characteristics and the relationships among samples. However, the extent of the impact of non-IID information and how these methods affect pre-trained language models (PLMs) remains unclear. This study revisits the assumption that non-IID information enhances PLMs to achieve performance improvements from a Bayesian perspective, which unearths and integrates non-IID and IID features. Furthermore, we proposed a multi-attribute multi-grained framework for PLM adaptations (M2A), which combines multi-attribute and multi-grained views to mitigate uncertainty in a lightweight manner. We evaluate M2A through prevalent text-understanding datasets and demonstrate its superior performance, mainly when data are implicitly non-IID, and PLMs scale larger.

The goal of Audio-Visual Segmentation (AVS) is to localize and segment the sounding source objects from the video frames. Researchers working on AVS suffer from limited datasets because hand-crafted annotation is expensive. Recent works attempt to overcome the challenge of limited data by leveraging the segmentation foundation model, SAM, prompting it with audio to enhance its ability to segment sounding source objects. While this approach alleviates the model's burden on understanding visual modality by utilizing pre-trained knowledge of SAM, it does not address the fundamental challenge of the limited dataset for learning audio-visual relationships. To address these limitations, we propose \textbf{AV2T-SAM}, a novel framework that bridges audio features with the text embedding space of pre-trained text-prompted SAM. Our method leverages multimodal correspondence learned from rich text-image paired datasets to enhance audio-visual alignment. Furthermore, we introduce a novel feature, $\mathbf{\textit{\textbf{f}}_{CLIP} \odot \textit{\textbf{f}}_{CLAP}}$, which emphasizes shared semantics of audio and visual modalities while filtering irrelevant noise. Experiments on the AVSBench dataset demonstrate state-of-the-art performance on both datasets of AVSBench. Our approach outperforms existing methods by effectively utilizing pretrained segmentation models and cross-modal semantic alignment.

Current emotional text-to-speech (TTS) systems face challenges in mimicking a broad spectrum of human emotions due to the inherent complexity of emotions and limitations in emotional speech datasets and models. This paper proposes a TTS framework that facilitates control over pleasure, arousal, and dominance, and can synthesize a diversity of emotional styles without requiring any emotional speech data during TTS training. We train an emotional attribute predictor using only categorical labels from speech data, aligning with psychological research and incorporating anchored dimensionality reduction on self-supervised learning (SSL) features. The TTS framework converts text inputs into phonetic tokens via an autoregressive language model and uses pseudo-emotional dimensions to guide the parallel prediction of fine-grained acoustic details. Experiments conducted on the LibriTTS dataset demonstrate that our framework can synthesize speech with enhanced naturalness and a variety of emotional styles by effectively controlling emotional dimensions, even without the inclusion of any emotional speech during TTS training.

The rapid advancement of AI-generated singing voices, which now closely mimic natural human singing and align seamlessly with musical scores, has led to heightened concerns for artists and the music industry. Unlike spoken voice, singing voice presents unique challenges due to its musical nature and the presence of strong background music, making singing voice deepfake detection (SVDD) a specialized field requiring focused attention. To promote SVDD research, we recently proposed the "SVDD Challenge," the very first research challenge focusing on SVDD for lab-controlled and in-the-wild bonafide and deepfake singing voice recordings. The challenge will be held in conjunction with the 2024 IEEE Spoken Language Technology Workshop (SLT 2024).

Cone-beam computed tomography (CBCT) is widely used in image-guided radiotherapy. Reconstructing CBCTs from limited-angle acquisitions (LA-CBCT) is highly desired for improved imaging efficiency, dose reduction, and better mechanical clearance. LA-CBCT reconstruction, however, suffers from severe under-sampling artifacts, making it a highly ill-posed inverse problem. Diffusion models can generate data/images by reversing a data-noising process through learned data distributions; and can be incorporated as a denoiser/regularizer in LA-CBCT reconstruction. In this study, we developed a diffusion model-based framework, prior frequency-guided diffusion model (PFGDM), for robust and structure-preserving LA-CBCT reconstruction. PFGDM uses a conditioned diffusion model as a regularizer for LA-CBCT reconstruction, and the condition is based on high-frequency information extracted from patient-specific prior CT scans which provides a strong anatomical prior for LA-CBCT reconstruction. Specifically, we developed two variants of PFGDM (PFGDM-A and PFGDM-B) with different conditioning schemes. PFGDM-A applies the high-frequency CT information condition until a pre-optimized iteration step, and drops it afterwards to enable both similar and differing CT/CBCT anatomies to be reconstructed. PFGDM-B, on the other hand, continuously applies the prior CT information condition in every reconstruction step, while with a decaying mechanism, to gradually phase out the reconstruction guidance from the prior CT scans. The two variants of PFGDM were tested and compared with current available LA-CBCT reconstruction solutions, via metrics including PSNR and SSIM. PFGDM outperformed all traditional and diffusion model-based methods. PFGDM reconstructs high-quality LA-CBCTs under very-limited gantry angles, allowing faster and more flexible CBCT scans with dose reductions.

Effectively and efficiently adapting a pre-trained language model (PLM) for human-centered text understanding (HCTU) is challenging since user tokens are million-level in most personalized applications and do not have concrete explicit semantics. A standard and parameter-efficient approach (e.g., LoRA) necessitates memorizing numerous suits of adapters for each user. In this work, we introduce a personalized LoRA (PLoRA) with a plug-and-play (PnP) framework for the HCTU task. PLoRA is effective, parameter-efficient, and dynamically deploying in PLMs. Moreover, a personalized dropout and a mutual information maximizing strategies are adopted and hence the proposed PLoRA can be well adapted to few/zero-shot learning scenarios for the cold-start issue. Experiments conducted on four benchmark datasets show that the proposed method outperforms existing methods in full/few/zero-shot learning scenarios for the HCTU task, even though it has fewer trainable parameters. For reproducibility, the code for this paper is available at: https://github.com/yoyo-yun/PLoRA.

The rise of singing voice synthesis presents critical challenges to artists and industry stakeholders over unauthorized voice usage. Unlike synthesized speech, synthesized singing voices are typically released in songs containing strong background music that may hide synthesis artifacts. Additionally, singing voices present different acoustic and linguistic characteristics from speech utterances. These unique properties make singing voice deepfake detection a relevant but significantly different problem from synthetic speech detection. In this work, we propose the singing voice deepfake detection task. We first present SingFake, the first curated in-the-wild dataset consisting of 28.93 hours of bonafide and 29.40 hours of deepfake song clips in five languages from 40 singers. We provide a train/validation/test split where the test sets include various scenarios. We then use SingFake to evaluate four state-of-the-art speech countermeasure systems trained on speech utterances. We find these systems lag significantly behind their performance on speech test data. When trained on SingFake, either using separated vocal tracks or song mixtures, these systems show substantial improvement. However, our evaluations also identify challenges associated with unseen singers, communication codecs, languages, and musical contexts, calling for dedicated research into singing voice deepfake detection. The SingFake dataset and related resources are available at https://www.singfake.org/.

Autonomous driving is an emerging technology that has advanced rapidly over the last decade. Modern transportation is expected to benefit greatly from a wise decision-making framework of autonomous vehicles, including the improvement of mobility and the minimization of risks and travel time. However, existing methods either ignore the complexity of environments only fitting straight roads, or ignore the impact on surrounding vehicles during optimization phases, leading to weak environmental adaptability and incomplete optimization objectives. To address these limitations, we propose a parameterized decision-making framework with multi-modal perception based on deep reinforcement learning, called AUTO. We conduct a comprehensive perception to capture the state features of various traffic participants around the autonomous vehicle, based on which we design a graph-based model to learn a state representation of the multi-modal semantic features. To distinguish between lane-following and lane-changing, we decompose an action of the autonomous vehicle into a parameterized action structure that first decides whether to change lanes and then computes an exact action to execute. A hybrid reward function takes into account aspects of safety, traffic efficiency, passenger comfort, and impact to guide the framework to generate optimal actions. In addition, we design a regularization term and a multi-worker paradigm to enhance the training. Extensive experiments offer evidence that AUTO can advance state-of-the-art in terms of both macroscopic and microscopic effectiveness.

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice. We achieved this by adapting and refining the large language model meta-AI (LLaMA) using a large dataset of 100,000 patient-doctor dialogues sourced from a widely used online medical consultation platform. These conversations were cleaned and anonymized to respect privacy concerns. In addition to the model refinement, we incorporated a self-directed information retrieval mechanism, allowing the model to access and utilize real-time information from online sources like Wikipedia and data from curated offline medical databases. The fine-tuning of the model with real-world patient-doctor interactions significantly improved the model's ability to understand patient needs and provide informed advice. By equipping the model with self-directed information retrieval from reliable online and offline sources, we observed substantial improvements in the accuracy of its responses. Our proposed ChatDoctor, represents a significant advancement in medical LLMs, demonstrating a significant improvement in understanding patient inquiries and providing accurate advice. Given the high stakes and low error tolerance in the medical field, such enhancements in providing accurate and reliable information are not only beneficial but essential.