Early prediction of Alzheimer's disease (AD) is crucial for timely intervention and treatment. This study aims to use machine learning approaches to analyze longitudinal electronic health records (EHRs) of patients with AD and identify signs and symptoms that can predict AD onset earlier. We used a case-control design with longitudinal EHRs from the U.S. Department of Veterans Affairs Veterans Health Administration (VHA) from 2004 to 2021. Cases were VHA patients with AD diagnosed after 1/1/2016 based on ICD-10-CM codes, matched 1:9 with controls by age, sex and clinical utilization with replacement. We used a panel of AD-related keywords and their occurrences over time in a patient's longitudinal EHRs as predictors for AD prediction with four machine learning models. We performed subgroup analyses by age, sex, and race/ethnicity, and validated the model in a hold-out and "unseen" VHA stations group. Model discrimination, calibration, and other relevant metrics were reported for predictions up to ten years before ICD-based diagnosis. The study population included 16,701 cases and 39,097 matched controls. The average number of AD-related keywords (e.g., "concentration", "speaking") per year increased rapidly for cases as diagnosis approached, from around 10 to over 40, while remaining flat at 10 for controls. The best model achieved high discriminative accuracy (ROCAUC 0.997) for predictions using data from at least ten years before ICD-based diagnoses. The model was well-calibrated (Hosmer-Lemeshow goodness-of-fit p-value = 0.99) and consistent across subgroups of age, sex and race/ethnicity, except for patients younger than 65 (ROCAUC 0.746). Machine learning models using AD-related keywords identified from EHR notes can predict future AD diagnoses, suggesting its potential use for identifying AD risk using EHR notes, offering an affordable way for early screening on large population.

Summarizing lengthy documents is a common and essential task in our daily lives. Although recent advancements in neural summarization models can assist in crafting general-purpose summaries, human writers often have specific requirements that call for a more customized approach. To address this need, we introduce REVISE (Refinement and Editing via Iterative Summarization Enhancement), an innovative framework designed to facilitate iterative editing and refinement of draft summaries by human writers. Within our framework, writers can effortlessly modify unsatisfactory segments at any location or length and provide optional starting phrases -- our system will generate coherent alternatives that seamlessly integrate with the existing summary. At its core, REVISE incorporates a modified fill-in-the-middle model with the encoder-decoder architecture while developing novel evaluation metrics tailored for the summarization task. In essence, our framework empowers users to create high-quality, personalized summaries by effectively harnessing both human expertise and AI capabilities, ultimately transforming the summarization process into a truly collaborative and adaptive experience.

Enhancing word usage is a desired feature for writing assistance. To further advance research in this area, this paper introduces "Smart Word Suggestions" (SWS) task and benchmark. Unlike other works, SWS emphasizes end-to-end evaluation and presents a more realistic writing assistance scenario. This task involves identifying words or phrases that require improvement and providing substitution suggestions. The benchmark includes human-labeled data for testing, a large distantly supervised dataset for training, and the framework for evaluation. The test data includes 1,000 sentences written by English learners, accompanied by over 16,000 substitution suggestions annotated by 10 native speakers. The training dataset comprises over 3.7 million sentences and 12.7 million suggestions generated through rules. Our experiments with seven baselines demonstrate that SWS is a challenging task. Based on experimental analysis, we suggest potential directions for future research on SWS. The dataset and related codes is available at https://github.com/microsoft/SmartWordSuggestions.

We present an empirical evaluation of various outputs generated by nine of the most widely-available large language models (LLMs). Our analysis is done with off-the-shelf, readily-available tools. We find a correlation between percentage of memorized text, percentage of unique text, and overall output quality, when measured with respect to output pathologies such as counterfactual and logically-flawed statements, and general failures like not staying on topic. Overall, 80.0% of the outputs evaluated contained memorized data, but outputs containing the most memorized content were also more likely to be considered of high quality. We discuss and evaluate mitigation strategies, showing that, in the models evaluated, the rate of memorized text being output is reduced. We conclude with a discussion on potential implications around what it means to learn, to memorize, and to evaluate quality text.

We introduce \textsc{PoliteRewrite} -- a dataset for polite language rewrite which is a novel sentence rewrite task. Compared with previous text style transfer tasks that can be mostly addressed by slight token- or phrase-level edits, polite language rewrite requires deep understanding and extensive sentence-level edits over an offensive and impolite sentence to deliver the same message euphemistically and politely, which is more challenging -- not only for NLP models but also for human annotators to rewrite with effort. To alleviate the human effort for efficient annotation, we first propose a novel annotation paradigm by a collaboration of human annotators and GPT-3.5 to annotate \textsc{PoliteRewrite}. The released dataset has 10K polite sentence rewrites annotated collaboratively by GPT-3.5 and human, which can be used as gold standard for training, validation and test; and 100K high-quality polite sentence rewrites by GPT-3.5 without human review. We wish this work (The dataset (10K+100K) will be released soon) could contribute to the research on more challenging sentence rewrite, and provoke more thought in future on resource annotation paradigm with the help of the large-scaled pretrained models.

Prompts with different control signals (e.g., length, keywords, etc.) can be used to control text summarization. When control signals are available, they can control the properties of generated summaries and potentially improve summarization quality (since more information are given). Unfortunately, control signals are not already available during inference time. In this paper, we propose Lotus (shorthand for Latent Prompt Tuning for Summarization), which is a single model that can be applied in both controlled and uncontrolled (without control signals) modes. During training, Lotus learns latent prompt representations from prompts with gold control signals using a contrastive learning objective. Experiments show Lotus in uncontrolled mode consistently improves upon strong (uncontrollable) summarization models across four different summarization datasets. We also demonstrate generated summaries can be controlled using prompts with user specified control tokens.

The input and output of most text generation tasks can be transformed to two sequences of tokens and they can be modeled using sequence-to-sequence learning modeling tools such as Transformers. These models are usually trained by maximizing the likelihood the output text sequence and assumes the input sequence and all gold preceding tokens are given during training, while during inference the model suffers from the exposure bias problem (i.e., it only has access to its previously predicted tokens rather gold tokens during beam search). In this paper, we propose MoCa ({\bf Mo}mentum {\bf Ca}libration) for text generation. MoCa is an online method that dynamically generates slowly evolving (but consistent) samples using a momentum moving average generator with beam search and MoCa learns to align its model scores of these samples with their actual qualities. Experiments on four text generation datasets (i.e., CNN/DailyMail, XSum, SAMSum and Gigaword) show MoCa consistently improves strong pre-trained transformers using vanilla fine-tuning and we achieve the state-of-the-art results on CNN/DailyMail and SAMSum datasets.

This paper aims for the task of text-to-video retrieval, where given a query in the form of a natural-language sentence, it is asked to retrieve videos which are semantically relevant to the given query, from a great number of unlabeled videos. The success of this task depends on cross-modal representation learning that projects both videos and sentences into common spaces for semantic similarity computation. In this work, we concentrate on video representation learning, an essential component for text-to-video retrieval. Inspired by the reading strategy of humans, we propose a Reading-strategy Inspired Visual Representation Learning (RIVRL) to represent videos, which consists of two branches: a previewing branch and an intensive-reading branch. The previewing branch is designed to briefly capture the overview information of videos, while the intensive-reading branch is designed to obtain more in-depth information. Moreover, the intensive-reading branch is aware of the video overview captured by the previewing branch. Such holistic information is found to be useful for the intensive-reading branch to extract more fine-grained features. Extensive experiments on three datasets are conducted, where our model RIVRL achieves a new state-of-the-art on TGIF and VATEX. Moreover, on MSR-VTT, our model using two video features shows comparable performance to the state-of-the-art using seven video features and even outperforms models pre-trained on the large-scale HowTo100M dataset.

Recent research on dense captioning based on the recurrent neural network and the convolutional neural network has made a great progress. However, mapping from an image feature space to a description space is a nonlinear and multimodel task, which makes it difficult for the current methods to get accurate results. In this paper, we put forward a novel approach for dense captioning based on hourglass-structured residual learning. Discriminant feature maps are obtained by incorporating dense connected networks and residual learning in our model. Finally, the performance of the approach on the Visual Genome V1.0 dataset and the region labelled MS-COCO (Microsoft Common Objects in Context) dataset are demonstrated. The experimental results have shown that our approach outperforms most current methods.

This paper introduces a novel neural network model for question answering, the \emph{entity-based memory network}. It enhances neural networks' ability of representing and calculating information over a long period by keeping records of entities contained in text. The core component is a memory pool which comprises entities' states. These entities' states are continuously updated according to the input text. Questions with regard to the input text are used to search the memory pool for related entities and answers are further predicted based on the states of retrieved entities. Compared with previous memory network models, the proposed model is capable of handling fine-grained information and more sophisticated relations based on entities. We formulated several different tasks as question answering problems and tested the proposed model. Experiments reported satisfying results.