Boosting is an ensemble method that combines base models in a sequential manner to achieve high predictive accuracy. A popular learning algorithm based on this ensemble method is eXtreme Gradient Boosting (XGB). We present an adaptation of XGB for classification of evolving data streams. In this setting, new data arrives over time and the relationship between the class and the features may change in the process, thus exhibiting concept drift. The proposed method creates new members of the ensemble from mini-batches of data as new data becomes available. The maximum ensemble size is fixed, but learning does not stop when this size is reached because the ensemble is updated on new data to ensure consistency with the current concept. We also explore the use of concept drift detection to trigger a mechanism to update the ensemble. We test our method on real and synthetic data with concept drift and compare it against batch-incremental and instance-incremental classification methods for data streams.

The family of methods collectively known as classifier chains has become a popular approach to multi-label learning problems. This approach involves linking together off-the-shelf binary classifiers in a chain structure, such that class label predictions become features for other classifiers. Such methods have proved flexible and effective and have obtained state-of-the-art empirical performance across many datasets and multi-label evaluation metrics. This performance led to further studies of how exactly it works, and how it could be improved, and in the recent decade numerous studies have explored classifier chains mechanisms on a theoretical level, and many improvements have been made to the training and inference procedures, such that this method remains among the state-of-the-art options for multi-label learning. Given this past and ongoing interest, which covers a broad range of applications and research themes, the goal of this work is to provide a review of classifier chains, a survey of the techniques and extensions provided in the literature, as well as perspectives for this approach in the domain of multi-label classification in the future. We conclude positively, with a number of recommendations for researchers and practitioners, as well as outlining a number of areas for future research.

De-identification of electronic health records (EHR) is a vital step towards advancing health informatics research and maximising the use of available data. It is a two-step process where step one is the identification of protected health information (PHI), and step two is replacing such PHI with surrogates. Despite the recent advances in automatic de-identification of EHR, significant obstacles remain if the abundant health data available are to be used to the full potential. Accuracy in de-identification could be considered a necessary, but not sufficient condition for the use of EHR without individual patient consent. We present here a comprehensive review of the progress to date, both the impressive successes in achieving high accuracy and the significant risks and challenges that remain. To best of our knowledge, this is the first paper to present a complete picture of end-to-end automatic de-identification. We review 18 recently published automatic de-identification systems -designed to de-identify EHR in the form of free text- to show the advancements made in improving the overall accuracy of the system, and in identifying individual PHI. We argue that despite the improvements in accuracy there remain challenges in surrogate generation and replacements of identified PHIs, and the risks posed to patient protection and privacy.

We present an online algorithm that induces decision trees using gradient information as the source of supervision. In contrast to previous approaches to gradient-based tree learning, we do not require soft splits or construction of a new tree for every update. In experiments, our method performs comparably to standard incremental classification trees and outperforms state of the art incremental regression trees. We also show how the method can be used to construct a novel type of neural network layer suited to learning representations from tabular data and find that it increases accuracy of multiclass and multi-label classification.

Use of medical data, also known as electronic health records, in research helps develop and advance medical science. However, protecting patient confidentiality and identity while using medical data for analysis is crucial. Medical data can be in the form of tabular structures (i.e. tables), free-form narratives, and images. This study focuses on medical data in the free form longitudinal text. De-identification of electronic health records provides the opportunity to use such data for research without it affecting patient privacy, and avoids the need for individual patient consent. In recent years there is increasing interest in developing an accurate, robust and adaptable automatic de-identification system for electronic health records. This is mainly due to the dilemma between the availability of an abundance of health data, and the inability to use such data in research due to legal and ethical restrictions. De-identification tracks in competitions such as the 2014 i2b2 UTHealth and the 2016 CEGS N-GRID shared tasks have provided a great platform to advance this area. The primary reasons for this include the open source nature of the dataset and the fact that raw psychiatric data were used for 2016 competitions. This study focuses on noticeable trend changes in the techniques used in the development of automatic de-identification for longitudinal clinical narratives. More specifically, the shift from using conditional random fields (CRF) based systems only or rules (regular expressions, dictionary or combinations) based systems only, to hybrid models (combining CRF and rules), and more recently to deep learning based systems. We review the literature and results that arose from the 2014 and the 2016 competitions and discuss the outcomes of these systems. We also provide a list of research questions that emerged from this survey.

A system of nested dichotomies is a method of decomposing a multi-class problem into a collection of binary problems. Such a system recursively applies binary splits to divide the set of classes into two subsets, and trains a binary classifier for each split. Many methods have been proposed to perform this split, each with various advantages and disadvantages. In this paper, we present a simple, general method for improving the predictive performance of nested dichotomies produced by any subset selection techniques that employ randomness to construct the subsets. We provide a theoretical expectation for performance improvements, as well as empirical results showing that our method improves the root mean squared error of nested dichotomies, regardless of whether they are employed as an individual model or in an ensemble setting.

Nested dichotomies are used as a method of transforming a multiclass classification problem into a series of binary problems. A tree structure is induced that recursively splits the set of classes into subsets, and a binary classification model learns to discriminate between the two subsets of classes at each node. In this paper, we demonstrate that these nested dichotomies typically exhibit poor probability calibration, even when the base binary models are well calibrated. We also show that this problem is exacerbated when the binary models are poorly calibrated. We discuss the effectiveness of different calibration strategies and show that accuracy and log-loss can be significantly improved by calibrating both the internal base models and the full nested dichotomy structure, especially when the number of classes is high.

Obtaining accurate and well calibrated probability estimates from classifiers is useful in many applications, for example, when minimising the expected cost of classifications. Existing methods of calibrating probability estimates are applied globally, ignoring the potential for improvements by applying a more fine-grained model. We propose probability calibration trees, a modification of logistic model trees that identifies regions of the input space in which different probability calibration models are learned to improve performance. We compare probability calibration trees to two widely used calibration methods---isotonic regression and Platt scaling---and show that our method results in lower root mean squared error on average than both methods, for estimates produced by a variety of base learners.

Effective regularisation of neural networks is essential to combat overfitting due to the large number of parameters involved. We present an empirical analogue to the Lipschitz constant of a feed-forward neural network, which we refer to as the maximum gain. We hypothesise that constraining the gain of a network will have a regularising effect, similar to how constraining the Lipschitz constant of a network has been shown to improve generalisation. A simple algorithm is provided that involves rescaling the weight matrix of each layer after each parameter update. We conduct a series of studies on common benchmark datasets, and also a novel dataset that we introduce to enable easier significance testing for experiments using convolutional networks. Performance on these datasets compares favourably with other common regularisation techniques.

We investigate the effect of explicitly enforcing the Lipschitz continuity of neural networks. Our main hypothesis is that constraining the Lipschitz constant of a networks will have a regularising effect. To this end, we provide a simple technique for computing the Lipschitz constant of a feed forward neural network composed of commonly used layer types. This technique is then utilised to formulate training a Lipschitz continuous neural network as a constrained optimisation problem, which can be easily solved using projected stochastic gradient methods. Our evaluation study shows that, in isolation, our method performs comparatively to state-of-the-art regularisation techniques. Moreover, when combined with existing approaches to regularising neural networks the performance gains are cumulative.