Advent of modern deep learning techniques has given rise to advancements in the field of Speech Emotion Recognition (SER). However, most systems prevalent in the field fail to generalize to speakers not seen during training. This study focuses on handling challenges of multilingual SER, specifically on unseen speakers. We introduce CAMuLeNet, a novel architecture leveraging co-attention based fusion and multitask learning to address this problem. Additionally, we benchmark pretrained encoders of Whisper, HuBERT, Wav2Vec2.0, and WavLM using 10-fold leave-speaker-out cross-validation on five existing multilingual benchmark datasets: IEMOCAP, RAVDESS, CREMA-D, EmoDB and CaFE and, release a novel dataset for SER on the Hindi language (BhavVani). CAMuLeNet shows an average improvement of approximately 8% over all benchmarks on unseen speakers determined by our cross-validation strategy.

This paper presents CrossVoice, a novel cascade-based Speech-to-Speech Translation (S2ST) system employing advanced ASR, MT, and TTS technologies with cross-lingual prosody preservation through transfer learning. We conducted comprehensive experiments comparing CrossVoice with direct-S2ST systems, showing improved BLEU scores on tasks such as Fisher Es-En, VoxPopuli Fr-En and prosody preservation on benchmark datasets CVSS-T and IndicTTS. With an average mean opinion score of 3.6 out of 4, speech synthesized by CrossVoice closely rivals human speech on the benchmark highlighting the efficacy of cascade-based systems and transfer learning in multilingual S2ST with prosody transfer. Transformer-based models (Vaswani et al., 2017) have revolutionized speech processing, leading to significant advancements in automatic speech recognition and text-to-speech technologies (Latif et al., 2023; Prabhavalkar et al., 2023). This shift towards end-to-end systems has opened new avenues in Speech-to-Speech Translation (S2ST) for translating speech across languages.

The field of prosody transfer in speech synthesis systems is rapidly advancing. This research is focused on evaluating learning methods for adapting pre-trained monolingual text-to-speech (TTS) models to multilingual conditions, i.e., Supervised Fine-Tuning (SFT) and Transfer Learning (TL). This comparison utilizes three distinct metrics: Mean Opinion Score (MOS), Recognition Accuracy (RA), and Mel Cepstral Distortion (MCD). Results demonstrate that, in comparison to SFT, TL leads to significantly enhanced performance, with an average MOS higher by 1.53 points, a 37.5% increase in RA, and approximately, a 7.8-point improvement in MCD. These findings are instrumental in helping build TTS models for low-resource languages.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyperparameters in different experimental settings. Here, we present a multi-modality cell segmentation benchmark, comprising over 1500 labeled images derived from more than 50 diverse biological experiments. The top participants developed a Transformer-based deeplearning algorithm that not only exceeds existing methods, but can also be applied to diverse microscopy images across imaging platforms and tissue types without manual parameter adjustments. This benchmark and the improved algorithm offer promising avenues for more accurate and versatile cell analysis in microscopy imaging. Cell segmentation is a fundamental task that is universally required for biological image analysis across a large number of different experimental settings and imaging modalities. For example, in multiplexed fluorescence image-based cancer microenvironment analysis, cell segmentation is the prerequisite for the identification of tumor sub-types, composition, and organization, which can lead to important biological insights [1]-[3]. However, the development of a universal and automatic cell segmentation technique continues to pose significant challenges due to the extensive diversity observed in microscopy images. This diversity arises from variations in cell origins, microscopy types, staining techniques, and cell morphologies. Recent advances [4], [5] have successfully demonstrated the feasibility of automatic and precise cellular segmentation for specific microscopy image types and cell types, such as fluorescence and mass spectrometry images [6], [7], differential interference contrast images of platelets [8], bacteria images [9] and yeast images [10], [11], but the selection of appropriate segmentation models remains a non-trivial task for non-expert users in conventional biology laboratories. Efforts have been made towards the development of generalized cell segmentation algorithms [9], [12], [13]. However, these algorithms were primarily trained using datasets consisting of gray-scale images and two-channel fluorescent images, lacking the necessary diversity to ensure robust generalization across a wide range of imaging modalities. For example, the segmentation models have struggled to perform effectively on RGB images, such as bone marrow aspirate slides stained with Jenner-Giemsa. Furthermore, these models often require manual selection of both the model type and the specific image channel to be segmented, posing challenges for biologists with limited computational expertise. Biomedical image data science competitions have emerged as an effective way to accelerate the development of cutting-edge algorithms [14], [15].

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multi-center study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and postprocessing (66%). The "typical" lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.