The paper surveys recent extensions of the Long-Short Term Memory networks to handle tree structures from the perspective of learning non-trivial forms of isomorph structured transductions. It provides a discussion of modern TreeLSTM models, showing the effect of the bias induced by the direction of tree processing. An empirical analysis is performed on real-world benchmarks, highlighting how there is no single model adequate to effectively approach all transduction problems.

Recurrent neural networks can learn complex transduction problems that require maintaining and actively exploiting a memory of their inputs. Such models traditionally consider memory and input-output functionalities indissolubly entangled. We introduce a novel recurrent architecture based on the conceptual separation between the functional input-output transformation and the memory mechanism, showing how they can be implemented through different neural components. By building on such conceptualization, we introduce the Linear Memory Network, a recurrent model comprising a feedforward neural network, realizing the non-linear functional transformation, and a linear autoencoder for sequences, implementing the memory component. The resulting architecture can be efficiently trained by building on closed-form solutions to linear optimization problems. Further, by exploiting equivalence results between feedforward and recurrent neural networks we devise a pretraining schema for the proposed architecture. Experiments on polyphonic music datasets show competitive results against gated recurrent networks and other state of the art models.

Extractive compression is a challenging natural language processing problem. This work contributes by formulating neural extractive compression as a parse tree transduction problem, rather than a sequence transduction task. Motivated by this, we introduce a deep neural model for learning structure-to-substructure tree transductions by extending the standard Long Short-Term Memory, considering the parent-child relationships in the structural recursion. The proposed model can achieve state of the art performance on sentence compression benchmarks, both in terms of accuracy and compression rate.

Hidden tree Markov models allow learning distributions for tree structured data while being interpretable as nondeterministic automata. We provide a concise summary of the main approaches in literature, focusing in particular on the causality assumptions introduced by the choice of a specific tree visit direction. We will then sketch a novel non-parametric generalization of the bottom-up hidden tree Markov model with its interpretation as a nondeterministic tree automaton with infinite states.

We introduce the Contextual Graph Markov Model, an approach combining ideas from generative models and neural networks for the processing of graph data. It founds on a constructive methodology to build a deep architecture comprising layers of probabilistic models that learn to encode the structured information in an incremental fashion. Context is diffused in an efficient and scalable way across the graph vertexes and edges. The resulting graph encoding is used in combination with discriminative models to address structure classification benchmarks.

The paper introduces concentric Echo State Network, an approach to design reservoir topologies that tries to bridge the gap between deterministically constructed simple cycle models and deep reservoir computing approaches. We show how to modularize the reservoir into simple unidirectional and concentric cycles with pairwise bidirectional jump connections between adjacent loops. We provide a preliminary experimental assessment showing how concentric reservoirs yield to superior predictive accuracy and memory capacity with respect to single cycle reservoirs and deep reservoir models.

Many of the current scientific advances in the life sciences have their origin in the intensive use of data for knowledge discovery. In no area this is so clear as in bioinformatics, led by technological breakthroughs in data acquisition technologies. It has been argued that bioinformatics could quickly become the field of research generating the largest data repositories, beating other data-intensive areas such as high-energy physics or astroinformatics. Over the last decade, deep learning has become a disruptive advance in machine learning, giving new live to the long-standing connectionist paradigm in artificial intelligence. Deep learning methods are ideally suited to large-scale data and, therefore, they should be ideally suited to knowledge discovery in bioinformatics and biomedicine at large. In this brief paper, we review key aspects of the application of deep learning in bioinformatics and medicine, drawing from the themes covered by the contributions to an ESANN 2018 special session devoted to this topic.

The paper presents a novel, principled approach to train recurrent neural networks from the Reservoir Computing family that are robust to missing part of the input features at prediction time. By building on the ensembling properties of Dropout regularization, we propose a methodology, named DropIn, which efficiently trains a neural model as a committee machine of subnetworks, each capable of predicting with a subset of the original input features. We discuss the application of the DropIn methodology in the context of Reservoir Computing models and targeting applications characterized by input sources that are unreliable or prone to be disconnected, such as in pervasive wireless sensor networks and ambient intelligence. We provide an experimental assessment using real-world data from such application domains, showing how the Dropin methodology allows to maintain predictive performances comparable to those of a model without missing features, even when 20\%-50\% of the inputs are not available.