The frequent breakdowns and malfunctions of industrial equipment have driven increasing interest in utilizing cost-effective and easy-to-deploy sensors, such as microphones, for effective condition monitoring of machinery. Microphones offer a low-cost alternative to widely used condition monitoring sensors with their high bandwidth and capability to detect subtle anomalies that other sensors might have less sensitivity. In this study, we investigate malfunctioning industrial machines to evaluate and compare anomaly detection performance across different machine types and fault conditions. Log-Mel spectrograms of machinery sound are used as input, and the performance is evaluated using the area under the curve (AUC) score for two different methods: baseline dense autoencoder (AE) and one-class deep Support Vector Data Description (deep SVDD) with different subspace dimensions. Our results over the MIMII sound dataset demonstrate that the deep SVDD method with a subspace dimension of 2 provides superior anomaly detection performance, achieving average AUC scores of 0.84, 0.80, and 0.69 for 6 dB, 0 dB, and -6 dB signal-to-noise ratios (SNRs), respectively, compared to 0.82, 0.72, and 0.64 for the baseline model. Moreover, deep SVDD requires 7.4 times fewer trainable parameters than the baseline dense AE, emphasizing its advantage in both effectiveness and computational efficiency.

Echocardiography is the most widely used imaging to monitor cardiac functions, serving as the first line in early detection of myocardial ischemia and infarction. However, echocardiography often suffers from several artifacts including sensor noise, lack of contrast, severe saturation, and missing myocardial segments which severely limit its usage in clinical diagnosis. In recent years, several machine learning methods have been proposed to improve echocardiography views. Yet, these methods usually address only a specific problem (e.g. denoising) and thus cannot provide a robust and reliable restoration in general. On the other hand, cardiac MRI provides a clean view of the heart without suffering such severe issues. However, due to its significantly higher cost, it is often only afforded by a few major hospitals, hence hindering its use and accessibility. In this pilot study, we propose a novel approach to transform echocardiography into the cardiac MRI view. For this purpose, Echo2MRI dataset, consisting of echocardiography and real cardiac MRI image pairs, is composed and will be shared publicly. A dedicated Cycle-consistent Generative Adversarial Network (Cycle-GAN) is trained to learn the transformation from echocardiography frames to cardiac MRI views. An extensive set of qualitative evaluations shows that the proposed transformer can synthesize high-quality artifact-free synthetic cardiac MRI views from a given sequence of echocardiography frames. Medical evaluations performed by a group of cardiologists further demonstrate that synthetic MRI views are indistinguishable from their original counterparts and are preferred over their initial sequence of echocardiography frames for diagnosis in 78.9% of the cases.

Myocardial infarction (MI) is a severe case of coronary artery disease (CAD) and ultimately, its detection is substantial to prevent progressive damage to the myocardium. In this study, we propose a novel view-fusion model named self-attention fusion network (SAF-Net) to detect MI from multi-view echocardiography recordings. The proposed framework utilizes apical 2-chamber (A2C) and apical 4-chamber (A4C) view echocardiography recordings for classification. Three reference frames are extracted from each recording of both views and deployed pre-trained deep networks to extract highly representative features. The SAF-Net model utilizes a self-attention mechanism to learn dependencies in extracted feature vectors. The proposed model is computationally efficient thanks to its compact architecture having three main parts: a feature embedding to reduce dimensionality, self-attention for view-pooling, and dense layers for the classification. Experimental evaluation is performed using the HMC-QU-TAU dataset which consists of 160 patients with A2C and A4C view echocardiography recordings. The proposed SAF-Net model achieves a high-performance level with 88.26% precision, 77.64% sensitivity, and 78.13% accuracy. The results demonstrate that the SAF-Net model achieves the most accurate MI detection over multi-view echocardiography recordings.

Restoration of poor quality images with a blended set of artifacts plays a vital role for a reliable diagnosis. Existing studies have focused on specific restoration problems such as image deblurring, denoising, and exposure correction where there is usually a strong assumption on the artifact type and severity. As a pioneer study in blind X-ray restoration, we propose a joint model for generic image restoration and classification: Restore-to-Classify Generative Adversarial Networks (R2C-GANs). Such a jointly optimized model keeps any disease intact after the restoration. Therefore, this will naturally lead to a higher diagnosis performance thanks to the improved X-ray image quality. To accomplish this crucial objective, we define the restoration task as an Image-to-Image translation problem from poor quality having noisy, blurry, or over/under-exposed images to high quality image domain. The proposed R2C-GAN model is able to learn forward and inverse transforms between the two domains using unpaired training samples. Simultaneously, the joint classification preserves the disease label during restoration. Moreover, the R2C-GANs are equipped with operational layers/neurons reducing the network depth and further boosting both restoration and classification performances. The proposed joint model is extensively evaluated over the QaTa-COV19 dataset for Coronavirus Disease 2019 (COVID-19) classification. The proposed restoration approach achieves over 90% F1-Score which is significantly higher than the performance of any deep model. Moreover, in the qualitative analysis, the restoration performance of R2C-GANs is approved by a group of medical doctors. We share the software implementation at https://github.com/meteahishali/R2C-GAN.

Coronavirus disease 2019 (COVID-19) has emerged the need for computer-aided diagnosis with automatic, accurate, and fast algorithms. Recent studies have applied Machine Learning algorithms for COVID-19 diagnosis over chest X-ray (CXR) images. However, the data scarcity in these studies prevents a reliable evaluation with the potential of overfitting and limits the performance of deep networks. Moreover, these networks can discriminate COVID-19 pneumonia usually from healthy subjects only or occasionally, from limited pneumonia types. Thus, there is a need for a robust and accurate COVID-19 detector evaluated over a large CXR dataset. To address this need, in this study, we propose a reliable COVID-19 detection network: ReCovNet, which can discriminate COVID-19 pneumonia from 14 different thoracic diseases and healthy subjects. To accomplish this, we have compiled the largest COVID-19 CXR dataset: QaTa-COV19 with 124,616 images including 4603 COVID-19 samples. The proposed ReCovNet achieved a detection performance with 98.57% sensitivity and 99.77% specificity.

Computer-aided diagnosis has become a necessity for accurate and immediate coronavirus disease 2019 (COVID-19) detection to aid treatment and prevent the spread of the virus. Numerous studies have proposed to use Deep Learning techniques for COVID-19 diagnosis. However, they have used very limited chest X-ray (CXR) image repositories for evaluation with a small number, a few hundreds, of COVID-19 samples. Moreover, these methods can neither localize nor grade the severity of COVID-19 infection. For this purpose, recent studies proposed to explore the activation maps of deep networks. However, they remain inaccurate for localizing the actual infestation making them unreliable for clinical use. This study proposes a novel method for the joint localization, severity grading, and detection of COVID-19 from CXR images by generating the so-called infection maps. To accomplish this, we have compiled the largest dataset with 119,316 CXR images including 2951 COVID-19 samples, where the annotation of the ground-truth segmentation masks is performed on CXRs by a novel collaborative human-machine approach. Furthermore, we publicly release the first CXR dataset with the ground-truth segmentation masks of the COVID-19 infected regions. A detailed set of experiments show that state-of-the-art segmentation networks can learn to localize COVID-19 infection with an F1-score of 83.20%, which is significantly superior to the activation maps created by the previous methods. Finally, the proposed approach achieved a COVID-19 detection performance with 94.96% sensitivity and 99.88% specificity.