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Efficient Neural Codes under Metabolic Constraints

Neural Information Processing Systems

Neural codes are inevitably shaped by various kinds of biological constraints, \emph{e.g.} noise and metabolic cost. Here we formulate a coding framework which explicitly deals with noise and the metabolic costs associated with the neural representation of information, and analytically derive the optimal neural code for monotonic response functions and arbitrary stimulus distributions. For a single neuron, the theory predicts a family of optimal response functions depending on the metabolic budget and noise characteristics. Interestingly, the well-known histogram equalization solution can be viewed as a special case when metabolic resources are unlimited. For a pair of neurons, our theory suggests that under more severe metabolic constraints, ON-OFF coding is an increasingly more efficient coding scheme compared to ON-ON or OFF-OFF. The advantage could be as large as one-fold, substantially larger than the previous estimation. Some of these predictions could be generalized to the case of large neural populations. In particular, these analytical results may provide a theoretical basis for the predominant segregation into ONand OFF-cells in early visual processing areas. Overall, we provide a unified framework for optimal neural codes with monotonic tuning curves in the brain, and makes predictions that can be directly tested with physiology experiments.


Deep Neural Networks with Inexact Matching for Person Re-Identification

Neural Information Processing Systems

Person Re-Identification is the task of matching images of a person across multiple camera views. Almost all prior approaches address this challenge by attempting to learn the possible transformations that relate the different views of a person from a training corpora. Then, they utilize these transformation patterns for matching a query image to those in a gallery image bank at test time.


Scan Order in Gibbs Sampling: Models in Which it Matters and Bounds on How Much

Neural Information Processing Systems

Gibbs sampling is a Markov Chain Monte Carlo sampling technique that iteratively samples variables from their conditional distributions. There are two common scan orders for the variables: random scan and systematic scan. Due to the benefits of locality in hardware, systematic scan is commonly used, even though most statistical guarantees are only for random scan. While it has been conjectured that the mixing times of random scan and systematic scan do not differ by more than a logarithmic factor, we show by counterexample that this is not the case, and we prove that that the mixing times do not differ by more than a polynomial factor under mild conditions. To prove these relative bounds, we introduce a method of augmenting the state space to study systematic scan using conductance.


Unsupervised Learning from Noisy Networks with Applications to Hi-C Data

Neural Information Processing Systems

Complex networks play an important role in a plethora of disciplines in natural sciences. Cleaning up noisy observed networks, poses an important challenge in network analysis Existing methods utilize labeled data to alleviate the noise effect in the network. However, labeled data is usually expensive to collect while unlabeled data can be gathered cheaply. In this paper, we propose an optimization framework to mine useful structures from noisy networks in an unsupervised manner. The key feature of our optimization framework is its ability to utilize local structures as well as global patterns in the network.


Learning Treewidth-Bounded Bayesian Networks with Thousands of Variables

Neural Information Processing Systems

We present a method for learning treewidth-bounded Bayesian networks from data sets containing thousands of variables. Bounding the treewidth of a Bayesian network greatly reduces the complexity of inferences. Yet, being a global property of the graph, it considerably increases the difficulty of the learning process. Our novel algorithm accomplishes this task, scaling both to large domains and to large treewidths. Our novel approach consistently outperforms the state of the art on experiments with up to thousands of variables.


Contextual semibandits via supervised learning oracles

Neural Information Processing Systems

We study an online decision making problem where on each round a learner chooses a list of items based on some side information, receives a scalar feedback value for each individual item, and a reward that is linearly related to this feedback. These problems, known as contextual semibandits, arise in crowdsourcing, recommendation, and many other domains. This paper reduces contextual semibandits to supervised learning, allowing us to leverage powerful supervised learning methods in this partial-feedback setting. Our first reduction applies when the mapping from feedback to reward is known and leads to a computationally efficient algorithm with near-optimal regret. We show that this algorithm outperforms state-of-the-art approaches on real-world learning-to-rank datasets, demonstrating the advantage of oracle-based algorithms. Our second reduction applies to the previously unstudied setting when the linear mapping from feedback to reward is unknown. Our regret guarantees are superior to prior techniques that ignore the feedback.


Scaled Least Squares Estimator for GLMs in Large-Scale Problems

Neural Information Processing Systems

We study the problem of efficiently estimating the coefficients of generalized linear models (GLMs) in the large-scale setting where the number of observations $n$ is much larger than the number of predictors $p$, i.e. $n\gg p \gg 1$. We show that in GLMs with random (not necessarily Gaussian) design, the GLM coefficients are approximately proportional to the corresponding ordinary least squares (OLS) coefficients. Using this relation, we design an algorithm that achieves the same accuracy as the maximum likelihood estimator (MLE) through iterations that attain up to a cubic convergence rate, and that are cheaper than any batch optimization algorithm by at least a factor of $\mathcal{O}(p)$. We provide theoretical guarantees for our algorithm, and analyze the convergence behavior in terms of data dimensions.


Kernel Bayesian Inference with Posterior Regularization

Neural Information Processing Systems

We propose a vector-valued regression problem whose solution is equivalent to the reproducing kernel Hilbert space (RKHS) embedding of the Bayesian posterior distribution. This equivalence provides a new understanding of kernel Bayesian inference. Moreover, the optimization problem induces a new regularization for the posterior embedding estimator, which is faster and has comparable performance to the squared regularization in kernel Bayes' rule. This regularization coincides with a former thresholding approach used in kernel POMDPs whose consistency remains to be established. Our theoretical work solves this open problem and provides consistency analysis in regression settings. Based on our optimizational formulation, we propose a flexible Bayesian posterior regularization framework which for the first time enables us to put regularization at the distribution level. We apply this method to nonparametric state-space filtering tasks with extremely nonlinear dynamics and show performance gains over all other baselines.


Joint quantile regression in vector-valued RKHSs

Neural Information Processing Systems

Addressing the will to give a more complete picture than an average relationship provided by standard regression, a novel framework for estimating and predicting simultaneously several conditional quantiles is introduced. The proposed methodology leverages kernel-based multi-task learning to curb the embarrassing phenomenon of quantile crossing, with a one-step estimation procedure and no post-processing. Moreover, this framework comes along with theoretical guarantees and an efficient coordinate descent learning algorithm. Numerical experiments on benchmark and real datasets highlight the enhancements of our approach regarding the prediction error, the crossing occurrences and the training time.


Faster Projection-free Convex Optimization over the Spectrahedron

Neural Information Processing Systems

Minimizing a convex function over the spectrahedron, i.e., the set of all $d\times d$ positive semidefinite matrices with unit trace, is an important optimization task with many applications in optimization, machine learning, and signal processing. It is also notoriously difficult to solve in large-scale since standard techniques require to compute expensive matrix decompositions. An alternative, is the conditional gradient method (aka Frank-Wolfe algorithm) that regained much interest in recent years, mostly due to its application to this specific setting. The key benefit of the CG method is that it avoids expensive matrix decompositions all together, and simply requires a single eigenvector computation per iteration, which is much more efficient.