TEXTAL: Crystallographic Protein Model Building Using AI and Pattern Recognition

TEXTAL is a computer program that automatically interprets electron density maps to determine the atomic structures of proteins through X-ray crystallography. Electron density maps are traditionally interpreted by visually fitting atoms into density patterns. This manual process can be time-consuming and error prone, even for expert crystallographers. To automate the process, TEXTAL employs a variety of AI and pattern-recognition techniques that emulate the decision-making processes of domain experts.