Export Reviews, Discussions, Author Feedback and Meta-Reviews

High-dimensional neural spike train analysis with generalized count linear dynamical systems This paper describes a general exponential-family model (called the "generalized count" (GC) distribution) for multi-neuron spike count data. The model accounts for both under-dispersed and over-dispersed spike count data, and has Poisson, Negative Binomial, Bernoulli, and several other classic models as special cases. The authors give a clear account of the relationship to other models, and demonstrate the need for a model to capture under-dispersed counts in primate motor cortex. They then describe an efficient method for maximum-likelihood fitting (and demonstrate concavity of the log-likelihood). They derive an efficient variational Bayesian inference method and apply the model to data from primate motor cortex, showing that it accounts more accurately for variance and cross-covariance of spike count data, compared to a model with Poisson observations.